Psoriasis as a Model to Study Inflammation and Cardiometabolic Diseases in Humans
NIH Director's Seminar Series
Inflammation is critical to atherosclerosis initiation, progression and complications. The goal of The Laboratory of Inflammation and Cardiometabolic Diseases, NHLBI, is to understand how chronic systemic inflammation drives development of cardiometabolic diseases in humans. Dr. Mehta ’ s research program has utilized psoriasis, a chronic inflammatory skin disease, as a model to probe inflammatory, lipid and metabolic pathways associated with atherosclerosis progression. In 2012, Dr. Mehta founded the Psoriasis Atherosclerosis Cardiometabolic Initiative (PACI) at the NHLBI Intramural Program...
Source: Videocast - All Events - October 19, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar Series: Psoriasis as a Model to Study Inflammation and Cardiometabolic Diseases in Humans
Inflammation is critical to atherosclerosis initiation, progression and complications. The goal of The Laboratory of Inflammation and Cardiometabolic Diseases, NHLBI, is to understand how chronic systemic inflammation drives development of cardiometabolic diseases in humans. Dr. Mehta ’ s research program has utilized psoriasis, a chronic inflammatory skin disease, as a model to probe inflammatory, lipid and metabolic pathways associated with atherosclerosis progression. In 2012, Dr. Mehta founded the Psoriasis Atherosclerosis Cardiometabolic Initiative (PACI) at the NHLBI Intramural Program when he was awarded the Inaug...
Source: Videocast - All Events - October 7, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Understanding the Effects of Inflammation over time in Humans: Lessons from Psoriasis
Inflammation is critical to atherosclerosis initiation, progression and complications. The goal of The Laboratory of Inflammation and Cardiometabolic Diseases at the NHLBI Intramural Program is to understand how chronic systemic inflammation drives development of cardiometabolic diseases in humans. For the past decade, Dr. Mehta ’ s research program has utilized psoriasis, a chronic inflammatory skin disease, as a model to probe inflammatory, lipid and metabolic pathways associated with atherosclerosis progression. In 2012, Dr. Mehta founded the Psoriasis Atherosclerosis Cardiometabolic Initiative (PACI) at the NHLBI Int...
Source: Videocast - All Events - February 18, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Kenneth Gordon, MD - Potential Clinical Implications of the Latest Data on Approved and Emerging Therapies for Psoriasis: A Recap From Washington, DC
Go online to PeerView.com/YDK860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in dermatology discusses select abstracts focused on psoriasis that were presented at the 2019 American Academy of Dermatology (AAD) Annual Meeting, held from March 1-5, in Washington, DC. An overview and practical insights are offered on new data that speak to a rapidly evolving treatment landscape in psoriasis. Upon completion of this activity, participants should be better able to: Apply new data on the efficacy, safety, and optimal clinical use of approved ther...
Source: Peerview CME/CE Video Podcast - Internal Medicine International - June 12, 2019 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Control of Skin Immunity by Non-Immune Cells
Immunonology IG Seminar
The skin is a barrier organ that is a frequent site of entry for numerous pathogens. The skin is able to resist infection through a variety of mechanisms including innate and adaptive immune responses. Resident memory T cells (TRM) are a recently appreciated subset of memory T cells that reside in the skin and are required for optimal protection against previously encountered pathogens. These cells also participate in a number of cutaneous autoimmune diseases including vitiligo, psoriasis and alopecia areata. The skin also contains several populations innate immune cells that provide pathogen protec...
Source: Videocast - All Events - October 3, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video
Oh to be seventeen again: IL-17 signaling in fungal immunity and autoimmune disease
Immunology Interest Group Seminar Series
The IL-17 family constitutes a distinct subclass of pro-inflammatory cytokines with unique structures and signaling properties. Signals from IL-17 mediate immunity to extracellular pathogens, particularly the commensal fungus Candida albicans. Conversely, dysregulated IL-17 signal transduction drives pathogenesis in autoimmune conditions, including psoriasis. This talk will discuss both sides of this dual-acting cytokine, from the perspective of IL-17 receptor-induced signal transduction mechanisms.
Biography: Dr. Sarah Gaffen received her BS in Biological Sciences from Carnegie Mel...
Source: Videocast - All Events - February 3, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video
April W. Armstrong, MD, MPH - Employing a Patient-Centered Approach to Improve Clinical Outcomes in Patients With Moderate to Severe Psoriasis
Employing a Patient-Centered Approach to Improve Clinical Outcomes in Patients With Moderate to Severe Psoriasis (Source: Peerview CME/CE Video Podcast - Internal Medicine International)
Source: Peerview CME/CE Video Podcast - Internal Medicine International - October 3, 2016 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Use of spherical nucleic acid nanoconjugates to accelerate closure of diabetic wounds
NIH Director's Wednesday Afternoon Lecture Series
The Paller lab studies the role of gangliosides (sphingolipids), which regulate lipid raft-based signaling, in skin, particularly in diabetic wound healing and skin cancer. The lab uses DNA- and RNA-nanoconjugates as topical gene therapy to treat diabetic ulcers, psoriasis, skin cancer and other skin overgrowth disorders, and rare genetic skin problems. Dr. Paller is the PI of Northwestern's Skin Disease Research Center, which includes 3 Cores dedicated to providing service to researchers of skin biology. As a pediatric dermatologist, Dr. Paller specializes in genetic (esp...
Source: Videocast - All Events - March 25, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
Steven R. Feldman, MD, PhD - Advances in the Treatment of Moderate to Severe Psoriasis: An Update From the 2014 European Academy of Dermatology and Venereology Annual Meeting
Advances in the Treatment of Moderate to Severe Psoriasis: An Update From the 2014 European Academy of Dermatology and Venereology Annual Meeting (Source: Peerview CME/CE Video Podcast - Rheumatology)
Source: Peerview CME/CE Video Podcast - Rheumatology - January 7, 2015 Category: Rheumatology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Steven R. Feldman, MD, PhD - Advances in the Treatment of Moderate to Severe Psoriasis: An Update From the 2014 European Academy of Dermatology and Venereology Annual Meeting
Advances in the Treatment of Moderate to Severe Psoriasis: An Update From the 2014 European Academy of Dermatology and Venereology Annual Meeting (Source: Peerview CME/CE Video Podcast - Rheumatology)
Source: Peerview CME/CE Video Podcast - Rheumatology - January 7, 2015 Category: Rheumatology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Neil J. Korman, MD, PhD - What's Now, What's Next: Individualizing the Treatment of Patients With Moderate to Severe Psoriasis for the Dermatologist
Neil J. Korman, MD, PhD - What's Now, What's Next: Individualizing the Treatment of Patients With Moderate to Severe Psoriasis for the Dermatologist (Source: Peerview CME/CE Video Podcast - Rheumatology)
Source: Peerview CME/CE Video Podcast - Rheumatology - December 31, 2014 Category: Rheumatology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Neil J. Korman, MD, PhD - What's Now, What's Next: Individualizing the Treatment of Patients With Moderate to Severe Psoriasis for the Dermatologist
(Source: Peerview CME/CE Video Podcast - Rheumatology)
Source: Peerview CME/CE Video Podcast - Rheumatology - December 31, 2014 Category: Rheumatology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Alan Menter, MD - Psoriasis: Individualizing Treatments Using Current and Emerging Therapies
Psoriasis: Individualizing Treatments Using Current and Emerging Therapies (Source: Peerview CME/CE Video Podcast - Rheumatology)
Source: Peerview CME/CE Video Podcast - Rheumatology - May 6, 2014 Category: Rheumatology Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
CC Grand Rounds: (1) The Use of Mesenchymal Stem Cells to Improve LV Function as an Adjunct to Surgical Revascularization (2) Psoriasis Inflammation and its Association with Cardiometabolic Disease
Presented by: (1) Keith Horvath, MD Director, Cardiothoracic Surgery Research Program, NHLBI, NIH Chief, Cardiothoracic Surgery, NIH Heart Center at Suburban Hospital; and Associate Professor, Johns Hopkins University School of Medicine (2) Nehal Mehta, MD, MSCE Category: Clinical Center Grand RoundsAired date: 02/19/2014 (Source: Videocast - All Events)
Source: Videocast - All Events - February 21, 2014 Category: Journals (General) Tags: Past Events Source Type: video
CC Grand Rounds: (1) The Use of Mesenchymal Stem Cells to Improve LV Function as an Adjunct to Surgical Revascularization (2) Psoriasis Inflammation and its Association with Cardiometabolic Disease
For more information go to http://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 2/19/2014 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 29, 2014 Category: Journals (General) Tags: Upcoming Events Source Type: video
