Treatment of plaque-psoriasis in HIV-positive patients
Acta Dermatovenerol Alp Pannonica Adriat. 2024 Mar;33(1):37-40.ABSTRACTPsoriasis is a chronic inflammatory disease that can often accompany human immunodeficiency virus (HIV) epidemics. Development of psoriasis in HIV patients is correlated with a decrease in CD4+ count. Significant variability in the clinical presentation of psoriasis makes it a challenging disease to diagnose. Furthermore, associated immunodeficiency complicates standard treatment with immunosuppressive and biological therapy. Articles that match the terms psoriasis and HIV were searched in MEDLINE and Embase and selected based on their relevance. Highly...
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - March 27, 2024 Category: Dermatology Authors: Vita Jugovac Marija Gulin Dora Bari ć Daniela Ledi ć Drvar Romana Čeović Source Type: research

Effects of secukinumab combined with tretinoin on metabolism, liver enzymes, and inflammatory factors in patients with moderate to severe psoriasis vulgaris
CONCLUSIONS: Secukinumab combined with tretinoin is more effective in MSP vulgaris, which can visibly reduce inflammatory response without affecting glucose and lipid metabolism and liver function.PMID:38533361 | PMC:PMC10962373 | DOI:10.5114/ada.2023.135605 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Yong Chen Mei Yi Xiaoyan Pang Mengfei Du Haizhou Chen Zhenshu Li Source Type: research

Long-term efficacy, safety, and drug survival of secukinumab in patients with psoriasis in Turkey: a retrospective analysis of real-world experience
CONCLUSIONS: Close monitoring may improve SEC survival in psoriasis patients who require dose escalation and concomitant drugs.PMID:38533357 | PMC:PMC10962371 | DOI:10.5114/ada.2023.135757 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Fatma Elif Y ıldırım Fatma Asl ı Hapa Source Type: research

Does the effectiveness of biological medications in the treatment for psoriasis depend on the moment of starting therapy? A preliminary study
CONCLUSIONS: Our understanding of the effectiveness of the treatments depending on the time of the year combined with the type of biologics used, may further improve results of the therapy.PMID:38533365 | PMC:PMC10962378 | DOI:10.5114/ada.2024.135917 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Micha ł Niedźwiedź Marcin Noweta Joanna Narbutt Witold Owczarek Magdalena Ci ążyńska Agnieszka Czerwi ńska Janusz Krzy ścin Aleksandra Lesiak Ma łgorzata Skibińska Source Type: research

Aryl hydrocarbon receptor role in chronic inflammatory skin diseases: a narrative review
In conclusion, the AHR is a pivotal player in dermatology, with a multifaceted role in skin physiology and pathology. Understanding the intricacies of AHR signalling in the skin offers promising avenues for the development of novel therapies and preventive strategies for various dermatological conditions. Further research is warranted to elucidate the full scope of AHR's contributions to dermatology and its potential as a therapeutic target.PMID:38533374 | PMC:PMC10962376 | DOI:10.5114/ada.2023.135617 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Micha ł Dec Hubert Arasiewicz Source Type: research