Real-life management of psoriasis with biological agents during pregnancy
DISCUSSION: The majority of practitioners do not follow recommendations on discontinuation of biologic agents before the planning of pregnancy by patients.PMID:38554588 | DOI:10.1016/j.annder.2024.103254 (Source: Annales de Dermatologie et de Cenereologie)
Source: Annales de Dermatologie et de Cenereologie - March 30, 2024 Category: Dermatology Authors: C Tran E Mah é M Beylot-Barry D Jullien M-A Richard A-C Fougerousse A Bouznad C Bulai Livideanu A Brun F Amelot F Maccari F Aubin F Benhadou C Paul Source Type: research

Real-life management of psoriasis with biological agents during pregnancy
DISCUSSION: The majority of practitioners do not follow recommendations on discontinuation of biologic agents before the planning of pregnancy by patients.PMID:38554588 | DOI:10.1016/j.annder.2024.103254 (Source: Annales de Dermatologie et de Cenereologie)
Source: Annales de Dermatologie et de Cenereologie - March 30, 2024 Category: Dermatology Authors: C Tran E Mah é M Beylot-Barry D Jullien M-A Richard A-C Fougerousse A Bouznad C Bulai Livideanu A Brun F Amelot F Maccari F Aubin F Benhadou C Paul Source Type: research

Real-life management of psoriasis with biological agents during pregnancy
DISCUSSION: The majority of practitioners do not follow recommendations on discontinuation of biologic agents before the planning of pregnancy by patients.PMID:38554588 | DOI:10.1016/j.annder.2024.103254 (Source: Annales de Dermatologie et de Venereologie)
Source: Annales de Dermatologie et de Venereologie - March 30, 2024 Category: Dermatology Authors: C Tran E Mah é M Beylot-Barry D Jullien M-A Richard A-C Fougerousse A Bouznad C Bulai Livideanu A Brun F Amelot F Maccari F Aubin F Benhadou C Paul Source Type: research

The implications of exosomes in psoriasis: disease: emerging as new diagnostic markers and therapeutic targets
Mol Biol Rep. 2024 Mar 29;51(1):465. doi: 10.1007/s11033-024-09449-x.ABSTRACTAs the largest human organ, the skin is continuously exposed to various external and internal triggers that affect body homeostasis. Psoriasis is a persistent inflammatory skin condition that has a major bearing on patients' physiological functioning as well as their mental well-being. It is an autoimmune disorder and has been the focus of extensive research efforts in recent years. Cells secrete exosomes into the environment surrounding them, which comprises a lipid bilayer. The movement of cellular components like microRNAs, mRNAs, DNA, lipids, ...
Source: Molecular Biology Reports - March 29, 2024 Category: Molecular Biology Authors: Zahra Akbari Jonoush Roya Mahdavi Masoumeh Farahani Fatemeh Zeinali Elahe Shayan Afshin Amari Source Type: research

The implications of exosomes in psoriasis: disease: emerging as new diagnostic markers and therapeutic targets
Mol Biol Rep. 2024 Mar 29;51(1):465. doi: 10.1007/s11033-024-09449-x.ABSTRACTAs the largest human organ, the skin is continuously exposed to various external and internal triggers that affect body homeostasis. Psoriasis is a persistent inflammatory skin condition that has a major bearing on patients' physiological functioning as well as their mental well-being. It is an autoimmune disorder and has been the focus of extensive research efforts in recent years. Cells secrete exosomes into the environment surrounding them, which comprises a lipid bilayer. The movement of cellular components like microRNAs, mRNAs, DNA, lipids, ...
Source: Mol Biol Cell - March 29, 2024 Category: Molecular Biology Authors: Zahra Akbari Jonoush Roya Mahdavi Masoumeh Farahani Fatemeh Zeinali Elahe Shayan Afshin Amari Source Type: research

Erratum to "Targeting upregulation of the immunosuppressive activity of MDSCs with indirubin as a novel strategy to alleviate psoriasis" [Int. Immunopharmacol. 123 (2023) 110710]
Int Immunopharmacol. 2024 Mar 28:111756. doi: 10.1016/j.intimp.2024.111756. Online ahead of print.NO ABSTRACTPMID:38553334 | DOI:10.1016/j.intimp.2024.111756 (Source: International Immunopharmacology)
Source: International Immunopharmacology - March 29, 2024 Category: Allergy & Immunology Authors: Yifei Hou Huimin Zhang Yangzhuangzhuang Zhu Xufeng He Wen Li Lin Su Mingxi Liu Xi Chen Fang Shen Xiao Chen Wencheng Jiang Chunpu Zou Zihang Xu Source Type: research

The implications of exosomes in psoriasis: disease: emerging as new diagnostic markers and therapeutic targets
Mol Biol Rep. 2024 Mar 29;51(1):465. doi: 10.1007/s11033-024-09449-x.ABSTRACTAs the largest human organ, the skin is continuously exposed to various external and internal triggers that affect body homeostasis. Psoriasis is a persistent inflammatory skin condition that has a major bearing on patients' physiological functioning as well as their mental well-being. It is an autoimmune disorder and has been the focus of extensive research efforts in recent years. Cells secrete exosomes into the environment surrounding them, which comprises a lipid bilayer. The movement of cellular components like microRNAs, mRNAs, DNA, lipids, ...
Source: Molecular Biology Reports - March 29, 2024 Category: Molecular Biology Authors: Zahra Akbari Jonoush Roya Mahdavi Masoumeh Farahani Fatemeh Zeinali Elahe Shayan Afshin Amari Source Type: research

The implications of exosomes in psoriasis: disease: emerging as new diagnostic markers and therapeutic targets
Mol Biol Rep. 2024 Mar 29;51(1):465. doi: 10.1007/s11033-024-09449-x.ABSTRACTAs the largest human organ, the skin is continuously exposed to various external and internal triggers that affect body homeostasis. Psoriasis is a persistent inflammatory skin condition that has a major bearing on patients' physiological functioning as well as their mental well-being. It is an autoimmune disorder and has been the focus of extensive research efforts in recent years. Cells secrete exosomes into the environment surrounding them, which comprises a lipid bilayer. The movement of cellular components like microRNAs, mRNAs, DNA, lipids, ...
Source: Mol Biol Cell - March 29, 2024 Category: Molecular Biology Authors: Zahra Akbari Jonoush Roya Mahdavi Masoumeh Farahani Fatemeh Zeinali Elahe Shayan Afshin Amari Source Type: research

Erratum to "Targeting upregulation of the immunosuppressive activity of MDSCs with indirubin as a novel strategy to alleviate psoriasis" [Int. Immunopharmacol. 123 (2023) 110710]
Int Immunopharmacol. 2024 Mar 28:111756. doi: 10.1016/j.intimp.2024.111756. Online ahead of print.NO ABSTRACTPMID:38553334 | DOI:10.1016/j.intimp.2024.111756 (Source: International Immunopharmacology)
Source: International Immunopharmacology - March 29, 2024 Category: Allergy & Immunology Authors: Yifei Hou Huimin Zhang Yangzhuangzhuang Zhu Xufeng He Wen Li Lin Su Mingxi Liu Xi Chen Fang Shen Xiao Chen Wencheng Jiang Chunpu Zou Zihang Xu Source Type: research

Microscopic Colitis and Risk of Incident Psoriasis: A Nationwide Population-Based Matched Cohort Study
(Source: Clinical Epidemiology)
Source: Clinical Epidemiology - March 29, 2024 Category: Epidemiology Tags: Clinical Epidemiology Source Type: research

Long-term safety and effectiveness of roflumilast cream 0.3% in adults with chronic plaque psoriasis: a 52-week, phase 2, open-label trial
Efficacy and/or safety profiles limit topical psoriasis treatments. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - March 29, 2024 Category: Dermatology Authors: Linda Stein Gold, David N. Adam, Lorne Albrecht, Javier Alonso-Llamazares, Laura K. Ferris, Melinda J. Gooderham, H. Chih-ho Hong, Steven E. Kempers, Leon H. Kircik, Mark Lebwohl, Wei Jing Loo, Walter K. Nahm, Kim A. Papp, Daniel Stewart, Darryl P. Toth, Source Type: research

Molecules, Vol. 29, Pages 1540: Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration
eta Patronova Aquaporin 3 (AQP3) channels are tetrameric membrane-bound channels that facilitate the transport of water and other small solutes across cell membranes in the skin. Decreased AQP3 expression is associated with skin dryness, skin aging, psoriasis, and delayed wound healing. Thus, our study focused on a novel combination based on Aloe barbadensis leaf extract and trimethylglycine for targeted AQP3 regulation in skin keratinocytes and deep skin moisturization. Firstly, a dose-finding cytotoxicity assay of the selected substances was performed with a 2,5-diphenyl-2H-tetrazolium bromide (MTT) indicator on HaCa...
Source: Molecules - March 29, 2024 Category: Chemistry Authors: Viktor Filatov Anna Sokolova Natalya Savitskaya Mariya Olkhovskaya Andrey Varava Egor Ilin Elizaveta Patronova Tags: Article Source Type: research

Development and Characterization of Transdermal Patches Using Novel Thymoquinone-L-Arginine-Based Polyamide Nanocapsules for Potential Use in the Management of Psoriasis
In conclusion, the produced formulation has a potential substitute for corticosteroids and other drugs commonly used to treat psoriasis due to its effectiveness, safety, and lack of the side effects typically associated with other drugs.PMID:38538972 | DOI:10.1208/s12249-024-02781-2 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - March 28, 2024 Category: Drugs & Pharmacology Authors: Eman Zmaily Dahmash Lama Murad Attiany Dalia Ali Shereen M Assaf Jamal Alkrad Hamad Alyami Source Type: research

Improving access to dermatology specialist care: review of a dermatologist- and general practitioner-integrated clinic model
This study presents an innovative model of integrated dermatology service delivery. Kauri HealthCare (KHC) is a general practice serving around 19 000 patients in Palmerston North, New Zealand. A 'mini clinic' is provided by an on-site dermatologist that is available for patients of KHC. Referring practitioners are required to attend with the patient to present their case and seek dermatologist input. This allows for patients to receive a specialist opinion, as well as for the referrer to receive practical and academic teaching, record findings, and arrange any further investigations, follow-up, or management. Aim To descr...
Source: Journal of Primary Health Care - March 28, 2024 Category: Primary Care Authors: Neakiry Kivi Louise Reiche Tanira Kingi Christina Elder Alex Semprini Source Type: research

Improving access to dermatology specialist care: review of a dermatologist- and general practitioner-integrated clinic model
This study presents an innovative model of integrated dermatology service delivery. Kauri HealthCare (KHC) is a general practice serving around 19 000 patients in Palmerston North, New Zealand. A 'mini clinic' is provided by an on-site dermatologist that is available for patients of KHC. Referring practitioners are required to attend with the patient to present their case and seek dermatologist input. This allows for patients to receive a specialist opinion, as well as for the referrer to receive practical and academic teaching, record findings, and arrange any further investigations, follow-up, or management. Aim To descr...
Source: Primary Care - March 28, 2024 Category: Primary Care Authors: Neakiry Kivi Louise Reiche Tanira Kingi Christina Elder Alex Semprini Source Type: research