Fight Aging! Newsletter, October 28th 2019
In this study, the enhanced mice live somewhat longer than their unmodified peers, though not as much longer as is the case for the application of telomerase gene therapy. The mice do also exhibit reduced cancer risk, however. The scientists here class telomere shortening as a cause of aging, which is not a point universally agreed upon. Reductions in average telomere length in tissues looks much more like a downstream consequence of reduced stem cell activity than an independent mechanism.
Researchers obtain the first mice born with hyper-long telomeres and show that it is possible to extend life without any geneti...
Source: Fight Aging! - October 27, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Treating Periodontitis Reduces Inflammatory Markers and Blood Pressure in Hypertensive Patients
Researchers here provide evidence for periodontitis, gum disease, to contribute to hypertension, chronic raised blood pressure, via inflammatory mechanisms. Aggressively treating the periodontitis in hypertensive patients reduces both blood pressure and inflammatory markers. Periodontitis has previously been linked with a modestly increased risk of dementia, as well as increased cardiovascular mortality risk. In both cases, increased inflammation is strongly suspected to be the linking mechanism.
Experimental and observational clinical evidence suggests a prominent role of inflammation in the development of hypert...
Source: Fight Aging! - October 22, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Harvard Health Ad Watch: What you should know about direct-to-consumer ads
If you’re like most people, you’ve seen a ton of direct-to-consumer (DTC) drug ads in recent years. They’re all over television, in magazines, online, on billboards, and slapped on the sides of buses, promoting treatments for arthritis, cancer, heartburn, psoriasis, flagging memory — and more. The deluge of drug ads can be overwhelming. Worse, the information is often incomplete, biased, or confusing. That’s why we’re launching the Harvard Health Ad Watch series to highlight some benefits and problems with health product advertisements. We’ll focus on the evidence behind the ads and show you how — a...
Source: Harvard Health Blog - September 20, 2019 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Children's Health Drugs and Supplements Men's Health Women's Health Source Type: blogs
5 Surprising Things Stress Can Do to Your Body
You're reading 5 Surprising Things Stress Can Do to Your Body, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles.
You just
got off a terrible meeting, your boss gave you an impossible deadline for the
next project, your team is pushing you to make extra hours, and you still need
to pick up the kids at school. Your body is in a “fight or flight response.”
Your stress levels are high, you feel your breath get quicker and even feel
your heart beating faster than usual. Although this is all a natural response
from your brai...
Source: PickTheBrain | Motivation and Self Improvement - June 18, 2019 Category: Consumer Health News Authors: annabelle Tags: featured health and fitness self improvement stress Source Type: blogs
Physicians can ’t do everything for everybody in every visit
How long does it take to diagnose guttate psoriasis versus pityriasis rosea? Swimmers ear versus a ruptured eardrum? A kidney stone? A urinary tract infection? An ankle sprain? So why is the typical “cycle time,” the time it takes for a patient to get through a clinic such as mine for these kinds of problems, […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - May 28, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/a-country-doctor" rel="tag" > Hans Duvefelt, MD < /a > < /span > Tags: Physician Primary Care Source Type: blogs
Brief is Good
By HANS DUVEFELT, MD
How long does it take to diagnose guttate psoriasis versus pityriasis rosea? Swimmers ear versus a ruptured eardrum? A kidney stone? A urinary tract infection? An ankle sprain?
So why is the typical “cycle time”, the time it takes for a patient to get through a clinic such as mine for these kinds of problems, close to an hour?
Answer: Mandated screening activities that could actually be done in different ways and not even necessarily in person or in real time!
Guess how many emergency room or urgent care center visits could be avoided and handled in the primary care office if we wer...
Source: The Health Care Blog - May 28, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians Hans Duvefelt primary care Source Type: blogs
Machine Learning Helps Design Complex Immunotherapies
This study demonstrates the potential of machine learning to support the bioengineering process, especially where there are many design variables and potential interplay between them.
Study in Nature Biomedical Engineering: Exploration of the nanomedicine-design space with high-throughput screening and machine learning
Via: Northwestern University… (Source: Medgadget)
Source: Medgadget - May 8, 2019 Category: Medical Devices Authors: Siavash Parkhideh Tags: Informatics Medicine Nanomedicine Source Type: blogs
Fight Aging! Newsletter, May 6th 2019
This study shows that mRNA levels of the aging related lamin A splice variant progerin, associated with premature aging in HGPS, were significantly upregulated in subjects with BMI ≥ 25 kg/m2. Moreover, our data revealed a significantly positive correlation of BMI with progerin mRNA. These data provide to our knowledge for the first-time evidence for a possible involvement of progerin in previously observed accelerated aging of overweight and obese individuals potentially limiting their longevity. Our results also showed that progerin mRNA was positively correlated with C-reactive protein (CRP). This might suggest an ass...
Source: Fight Aging! - May 5, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Chronic Inflammation as Proximate Cause of a Large Fraction of Age-Related Disease
This popular science article discusses at length the chronic inflammation that is characteristic of the old, and its role as a proximate cause of age-related disease. Inflammation is a necessary part of the immune response to injury and pathogens, and when present in the short term it is vital to the proper operation of bodily systems. But when the immune system runs awry in later life, and inflammatory processes are constantly running, then this inflammation corrodes metabolism, tissue function, and health.
The causes of excess, constant inflammation are both internal and external to the immune system. Internally, ...
Source: Fight Aging! - April 30, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Ten reasons to never eat wheat
How can conventional dietary advice gotten it so wrong?
Rather than eating plenty of “healthy whole grains,” people on the Wheat Belly lifestyle eat absolutely no grains and enjoy spectacular weight loss and reversal of hundreds of health conditions as a result. Unfortunately, many people view this as a “gluten-free” lifestyle which is incorrect.
Here are 10 reasons why no bagels, pretzels, or sandwiches made from wheat flour should ever cross human lips.
Gliadin-derived opioid peptides (from partial digestion to 4- and 5-amino acid long fragments) increase appetite substantially–as do related pro...
Source: Wheat Belly Blog - April 14, 2019 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle Gliadin gluten Inflammation Weight Loss Source Type: blogs
Manage Stress for Better Health: Some Tips
Discussions with Elders about HousingTips For Transitioning Care from Family to FacilityAging Parents: Where Do They Want to Live Their Last Years? (Source: Minding Our Elders)
Source: Minding Our Elders - March 12, 2019 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs
Clean cosmetics: The science behind the trend
Walking into the skin care aisle at the pharmacy, stepping up to a counter at a department store, or stopping by a cosmetics shop can be an overwhelming experience. Everywhere you look, you see products touting the ideal skin care ingredient. Who knew buying a moisturizer could be so difficult?
Lately, the coverage of “clean” cosmetics is everywhere — on national television and in best-selling books. It’s clear that clean is the newest beauty trend. But what is the clean cosmetics movement, and does the science support it?
Regulatory oversight of cosmetics: A brief history
The clean cosmetics movement seems to have...
Source: Harvard Health Blog - March 4, 2019 Category: Consumer Health News Authors: Molly Wanner, MD Tags: Allergies Health Skin and Hair Care Source Type: blogs
TREMFYA One-Press Patient Controlled Injector Approved for Plaque Psoriasis
The Janssen Pharma, a part of Johnson & Johnson, won FDA approval for its TREMFYA One-Press single-dose injector. The device is used to deliver TREMFYA (guselkumab) as a treatment for moderate to severe plaque psoriasis.
The TREMFYA One-Press allows patients to decide how fast and with how much pressure to deliver the medication. This lets everyone decide how much discomfort they will put up with, while everyone gets the required 100 mg during every injection.
The needle is completely hidden and only comes out when the device is placed against the skin and activated. Physicians are expected to teach patients how to u...
Source: Medgadget - February 27, 2019 Category: Medical Devices Authors: Editors Tags: Dermatology Medicine Source Type: blogs
Could that rash be from wheat?
Grains can play havoc with your skin. The prolamin proteins, such as gliadin, trigger autoimmune skin reactions and turn antibodies against the skin enzymes, their lectins fan the fires of inflammation, their proteins provoke allergies, and their amylopectins send blood sugar and insulin sky-high and provoke the skin-disrupting hormone insulin-like growth factor-1 (IGF). The whole grain package adds up to an impressive collection of skin conditions that can take a variety of forms, from simple red, itchy rashes to scaly, oily raised patches to large vesicles to gangrene. Because hair and nails are also considere...
Source: Wheat Belly Blog - February 20, 2019 Category: Cardiology Authors: Dr. Davis Tags: News & Updates Source Type: blogs
Are Grains to Blame for That Rash Too?
Grains can play havoc with your skin. The prolamin proteins, such as gliadin, trigger autoimmune skin reactions and turn antibodies against the skin enzymes, their lectins fan the fires of inflammation, their proteins provoke allergies, and their amylopectins send blood sugar and insulin sky-high and provoke the skin-disrupting hormone insulin-like growth factor-1 (IGF). The whole grain package adds up to an impressive collection of skin conditions that can take a variety of forms, from simple red, itchy rashes to scaly, oily raised patches to large vesicles to gangrene. Because hair and nails are also considere...
Source: Wheat Belly Blog - February 20, 2019 Category: Cardiology Authors: Dr. Davis Tags: News & Updates Source Type: blogs
