Cancers, Vol. 15, Pages 3482: Comparative In Silico Analysis of Ultra-Hypofractionated Intensity-Modulated Photon Radiotherapy (IMRT) Versus Intensity-Modulated Proton Therapy (IMPT) in the Pre-Operative Treatment of Retroperitoneal Sarcoma
Conclusions: IMPT maintained target coverage while significantly reducing the dose to adjacent OARs and integral dose compared to IMRT. A prospective trial treating RPS with pre-operative ultra-hypofractionated IMPT at our institution is currently being pursued. (Source: Cancers)
Source: Cancers - July 4, 2023 Category: Cancer & Oncology Authors: Emile Gogineni Hao Chen Alexandra C. Istl Fabian M. Johnston Amol Narang Curtiland Deville Tags: Article Source Type: research
A systematic review of volumetric image guidance in proton therapy
This article reviews the reported clinical use of volumetric IGPT, as available in published literature, and summarises their utilisation and workflow where possible. In addition, novel volumetric imaging systems are also briefly summarised highlighting their potential benefits for IGPT and the challenges that need to be overcome before they can be used clinically.PMID:37382744 | DOI:10.1007/s13246-023-01294-9 (Source: Health Physics)
Source: Health Physics - June 29, 2023 Category: Physics Authors: Mitchell Herrick Scott Penfold Alexandre Santos Kevin Hickson Source Type: research
Dosimetric comparison of autocontouring techniques for online adaptive proton therapy
Phys Med Biol. 2023 Jun 29. doi: 10.1088/1361-6560/ace307. Online ahead of print.ABSTRACTanatomical and daily set-up uncertainties impede high precision delivery of proton therapy. With online adaptation, the daily plan is reoptimized on an image taken shortly before the treatment, reducing these uncertainties and, hence, allowing a more accurate delivery. This reoptimization requires target and organs-at-risk (OAR) contours on the daily image, which need to be delineated automatically since manual contouring is too slow. Whereas multiple methods for autocontouring exist, none of them are fully accurate, which affects the ...
Source: Physics in Medicine and Biology - June 29, 2023 Category: Physics Authors: Andreas Johan Smolders Evangelia Choulilitsa Katarzyna Czerska Nicola Bizzocchi Reinhardt Krcek Antony John Lomax Damien Charles Weber Francesca Albertini Source Type: research
A systematic review of volumetric image guidance in proton therapy
This article reviews the reported clinical use of volumetric IGPT, as available in published literature, and summarises their utilisation and workflow where possible. In addition, novel volumetric imaging systems are also briefly summarised highlighting their potential benefits for IGPT and the challenges that need to be overcome before they can be used clinically.PMID:37382744 | DOI:10.1007/s13246-023-01294-9 (Source: Health Physics)
Source: Health Physics - June 29, 2023 Category: Physics Authors: Mitchell Herrick Scott Penfold Alexandre Santos Kevin Hickson Source Type: research
Dosimetric comparison of autocontouring techniques for online adaptive proton therapy
Phys Med Biol. 2023 Jun 29. doi: 10.1088/1361-6560/ace307. Online ahead of print.ABSTRACTanatomical and daily set-up uncertainties impede high precision delivery of proton therapy. With online adaptation, the daily plan is reoptimized on an image taken shortly before the treatment, reducing these uncertainties and, hence, allowing a more accurate delivery. This reoptimization requires target and organs-at-risk (OAR) contours on the daily image, which need to be delineated automatically since manual contouring is too slow. Whereas multiple methods for autocontouring exist, none of them are fully accurate, which affects the ...
Source: Physics in Medicine and Biology - June 29, 2023 Category: Physics Authors: Andreas Johan Smolders Evangelia Choulilitsa Katarzyna Czerska Nicola Bizzocchi Reinhardt Krcek Antony John Lomax Damien Charles Weber Francesca Albertini Source Type: research
Dosimetric comparison of autocontouring techniques for online adaptive proton therapy
Phys Med Biol. 2023 Jun 29. doi: 10.1088/1361-6560/ace307. Online ahead of print.ABSTRACTanatomical and daily set-up uncertainties impede high precision delivery of proton therapy. With online adaptation, the daily plan is reoptimized on an image taken shortly before the treatment, reducing these uncertainties and, hence, allowing a more accurate delivery. This reoptimization requires target and organs-at-risk (OAR) contours on the daily image, which need to be delineated automatically since manual contouring is too slow. Whereas multiple methods for autocontouring exist, none of them are fully accurate, which affects the ...
Source: Physics in Medicine and Biology - June 29, 2023 Category: Physics Authors: Andreas Johan Smolders Evangelia Choulilitsa Katarzyna Czerska Nicola Bizzocchi Reinhardt Krcek Antony John Lomax Damien Charles Weber Francesca Albertini Source Type: research
Dosimetric comparison of autocontouring techniques for online adaptive proton therapy
Phys Med Biol. 2023 Jun 29. doi: 10.1088/1361-6560/ace307. Online ahead of print.ABSTRACTanatomical and daily set-up uncertainties impede high precision delivery of proton therapy. With online adaptation, the daily plan is reoptimized on an image taken shortly before the treatment, reducing these uncertainties and, hence, allowing a more accurate delivery. This reoptimization requires target and organs-at-risk (OAR) contours on the daily image, which need to be delineated automatically since manual contouring is too slow. Whereas multiple methods for autocontouring exist, none of them are fully accurate, which affects the ...
Source: Physics in Medicine and Biology - June 29, 2023 Category: Physics Authors: Andreas Johan Smolders Evangelia Choulilitsa Katarzyna Czerska Nicola Bizzocchi Reinhardt Krcek Antony John Lomax Damien Charles Weber Francesca Albertini Source Type: research
Dosimetric comparison of autocontouring techniques for online adaptive proton therapy
Phys Med Biol. 2023 Jun 29. doi: 10.1088/1361-6560/ace307. Online ahead of print.ABSTRACTanatomical and daily set-up uncertainties impede high precision delivery of proton therapy. With online adaptation, the daily plan is reoptimized on an image taken shortly before the treatment, reducing these uncertainties and, hence, allowing a more accurate delivery. This reoptimization requires target and organs-at-risk (OAR) contours on the daily image, which need to be delineated automatically since manual contouring is too slow. Whereas multiple methods for autocontouring exist, none of them are fully accurate, which affects the ...
Source: Physics in Medicine and Biology - June 29, 2023 Category: Physics Authors: Andreas Johan Smolders Evangelia Choulilitsa Katarzyna Czerska Nicola Bizzocchi Reinhardt Krcek Antony John Lomax Damien Charles Weber Francesca Albertini Source Type: research
Dosimetric comparison of autocontouring techniques for online adaptive proton therapy
Phys Med Biol. 2023 Jun 29. doi: 10.1088/1361-6560/ace307. Online ahead of print.ABSTRACTanatomical and daily set-up uncertainties impede high precision delivery of proton therapy. With online adaptation, the daily plan is reoptimized on an image taken shortly before the treatment, reducing these uncertainties and, hence, allowing a more accurate delivery. This reoptimization requires target and organs-at-risk (OAR) contours on the daily image, which need to be delineated automatically since manual contouring is too slow. Whereas multiple methods for autocontouring exist, none of them are fully accurate, which affects the ...
Source: Physics in Medicine and Biology - June 29, 2023 Category: Physics Authors: Andreas Johan Smolders Evangelia Choulilitsa Katarzyna Czerska Nicola Bizzocchi Reinhardt Krcek Antony John Lomax Damien Charles Weber Francesca Albertini Source Type: research
A sinonasal NUT midline carcinoma in an 84 ‐year‐old man undergoing radiation and proton therapy
This is a report of an elderly patient with a NUT midline carcinoma involving the BRD4-NUTM1 fusion gene, undergoing radiation and proton therapy. NUT midline carcinomas are rare, aggressive, and poorly differentiated tumors that are infrequently reported in literature. To our knowledge, this is the oldest patient reported in the literature, and hopefully, the adopted treatment could be a suitable option in future presentations. AbstractNUT midline carcinomas are rare, aggressive, and poorly differentiated tumors that must be considered in the differential diagnosis of midline head and neck tumors. Despite the scarce data,...
Source: Clinical Case Reports - June 29, 2023 Category: General Medicine Authors: Katherynn Zhang,
Francisco Laxague,
Christina MacMillan,
S. Danielle MacNeil,
Kevin Fung,
John Yoo,
Anthony C. Nichols,
Adrian Mendez Tags: CASE REPORT Source Type: research
A systematic review of volumetric image guidance in proton therapy
This article reviews the reported clinical use of volumetric IGPT, as available in published literature, and summarises their utilisation and workflow where possible. In addition, novel volumetric imaging systems are also briefly summarised highlighting their potential benefits for IGPT and the challenges that need to be overcome before they can be used clinically. (Source: Australasian Physical and Engineering Sciences in Medicine)
Source: Australasian Physical and Engineering Sciences in Medicine - June 29, 2023 Category: Biomedical Engineering Source Type: research
Deterioration of Visual Acuity after Brachytherapy and Proton Therapy of Uveal Melanoma, and Methods of Counteracting This Complication Based on Recent Publications
This article is a review of the latest research on ruthenium-106 (Ru-106) brachytherapy, iodine-125 (I-125) brachytherapy and proton therapy of uveal melanoma that took into account the deterioration of eye function after therapy, and also the latest studies presenting the new concepts of modifications to the applied treatments in order to reduce radiation complications and maintain better visual acuity in treated patients.PMID:37374335 | DOI:10.3390/medicina59061131 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - June 28, 2023 Category: Universities & Medical Training Authors: Jakub Jarczak Izabella Karska-Basta Bo żena Romanowska-Dixon Source Type: research
PETRA: A pencil beam trimming algorithm for analytical proton therapy dose calculations with the dynamic collimation system
CONCLUSION: The PETRA model for DCS dose calculations was successfully defined and benchmarked for use in a commercially available TPS.PMID:37370239 | DOI:10.1002/mp.16559 (Source: Health Physics)
Source: Health Physics - June 28, 2023 Category: Physics Authors: Laura C Bennett Daniel E Hyer Kevin Erhart Nicholas P Nelson Wesley S Culberson Blake R Smith Patrick M Hill Ryan T Flynn Source Type: research
Deterioration of Visual Acuity after Brachytherapy and Proton Therapy of Uveal Melanoma, and Methods of Counteracting This Complication Based on Recent Publications
This article is a review of the latest research on ruthenium-106 (Ru-106) brachytherapy, iodine-125 (I-125) brachytherapy and proton therapy of uveal melanoma that took into account the deterioration of eye function after therapy, and also the latest studies presenting the new concepts of modifications to the applied treatments in order to reduce radiation complications and maintain better visual acuity in treated patients.PMID:37374335 | PMC:PMC10303310 | DOI:10.3390/medicina59061131 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - June 28, 2023 Category: Universities & Medical Training Authors: Jakub Jarczak Izabella Karska-Basta Bo żena Romanowska-Dixon Source Type: research
PETRA: A pencil beam trimming algorithm for analytical proton therapy dose calculations with the dynamic collimation system
CONCLUSION: The PETRA model for DCS dose calculations was successfully defined and benchmarked for use in a commercially available TPS.PMID:37370239 | DOI:10.1002/mp.16559 (Source: Health Physics)
Source: Health Physics - June 28, 2023 Category: Physics Authors: Laura C Bennett Daniel E Hyer Kevin Erhart Nicholas P Nelson Wesley S Culberson Blake R Smith Patrick M Hill Ryan T Flynn Source Type: research
