Proton Radiosurgery: Current Concepts and Limitations for CNS Radiosurgery
CONCLUSIONS: PSRS is effective and safe for various intracranial pathologies. Limited data, usually retrospective and single institution series exist. There are numerous advantages of protons over photons, so it is important to understand limitations with further studies. Published clinical outcomes and widespread adoption of proton therapy will be key to unlocking the potential benefits of PSRS.PMID:37026350 | DOI:10.4103/0028-3886.373636 (Source: Cancer Control)
Source: Cancer Control - April 7, 2023 Category: Cancer & Oncology Authors: Alonso La Rosa Andrew Wroe Zachary Fellows Rupesh Kotecha Source Type: research

Dose mimicking based strategies for online adaptive proton therapy of head and neck cancer
Phys Med Biol. 2023 Apr 6. doi: 10.1088/1361-6560/accb38. Online ahead of print.ABSTRACTTo compare a not adapted (NA) robust planning strategy with three fully automated online adaptive proton therapy (OAPT) workflows based on the same optimization method: dose mimicking (DM). The added clinical value and limitations of the OAPT methods are investigated for head and neck cancer (HNC) patients.


Approach: The three OAPT strategies aimed at compensating for inter-fractional anatomical changes by mimiking different dose distributions on corrected cone beam CT images (corrCBCTs). Order by complexity, t...
Source: Physics in Medicine and Biology - April 6, 2023 Category: Physics Authors: Elena Lucia Borderias Villarroel Albin Fredriksson Sophie Cvilic Dario Di Perri Eleonore Longton Julien Pierrard Xavier Geets Edmond Sterpin Source Type: research

Dose mimicking based strategies for online adaptive proton therapy of head and neck cancer
Phys Med Biol. 2023 Apr 6. doi: 10.1088/1361-6560/accb38. Online ahead of print.ABSTRACTTo compare a not adapted (NA) robust planning strategy with three fully automated online adaptive proton therapy (OAPT) workflows based on the same optimization method: dose mimicking (DM). The added clinical value and limitations of the OAPT methods are investigated for head and neck cancer (HNC) patients.


Approach: The three OAPT strategies aimed at compensating for inter-fractional anatomical changes by mimiking different dose distributions on corrected cone beam CT images (corrCBCTs). Order by complexity, t...
Source: Physics in Medicine and Biology - April 6, 2023 Category: Physics Authors: Elena Lucia Borderias Villarroel Albin Fredriksson Sophie Cvilic Dario Di Perri Eleonore Longton Julien Pierrard Xavier Geets Edmond Sterpin Source Type: research

Dose mimicking based strategies for online adaptive proton therapy of head and neck cancer
Phys Med Biol. 2023 Apr 6. doi: 10.1088/1361-6560/accb38. Online ahead of print.ABSTRACTTo compare a not adapted (NA) robust planning strategy with three fully automated online adaptive proton therapy (OAPT) workflows based on the same optimization method: dose mimicking (DM). The added clinical value and limitations of the OAPT methods are investigated for head and neck cancer (HNC) patients.


Approach: The three OAPT strategies aimed at compensating for inter-fractional anatomical changes by mimiking different dose distributions on corrected cone beam CT images (corrCBCTs). Order by complexity, t...
Source: Physics in Medicine and Biology - April 6, 2023 Category: Physics Authors: Elena Lucia Borderias Villarroel Albin Fredriksson Sophie Cvilic Dario Di Perri Eleonore Longton Julien Pierrard Xavier Geets Edmond Sterpin Source Type: research

Dose mimicking based strategies for online adaptive proton therapy of head and neck cancer
Phys Med Biol. 2023 Apr 6. doi: 10.1088/1361-6560/accb38. Online ahead of print.ABSTRACTTo compare a not adapted (NA) robust planning strategy with three fully automated online adaptive proton therapy (OAPT) workflows based on the same optimization method: dose mimicking (DM). The added clinical value and limitations of the OAPT methods are investigated for head and neck cancer (HNC) patients.


Approach: The three OAPT strategies aimed at compensating for inter-fractional anatomical changes by mimiking different dose distributions on corrected cone beam CT images (corrCBCTs). Order by complexity, t...
Source: Physics in Medicine and Biology - April 6, 2023 Category: Physics Authors: Elena Lucia Borderias Villarroel Albin Fredriksson Sophie Cvilic Dario Di Perri Eleonore Longton Julien Pierrard Xavier Geets Edmond Sterpin Source Type: research