Popular Heartburn Drugs Linked to Heightened COVID-19 Risk
A popular form of heartburn medication may increase a person’s risk of developing COVID-19, according to a new study, lengthening the already long list of risk factors for the virus.
In the study, published Tuesday in pre-print form in the American Journal of Gastroenterology, scientists led by Cedars-Sinai Medical Center’s Dr. Brennan Spiegel conducted an online survey involving more than 86,000 people. Among them, more than 53,000 reported abdominal pain or discomfort, acid reflux, heartburn or regurgitation, and answered questions about the medications they took to relieve those symptoms. Of those, more than...
Source: TIME: Health - July 7, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news
Proton Pump Inhibitor Therapy May Up Fracture Risk in Children
THURSDAY, April 2, 2020 -- Proton pump inhibitors (PPIs) taken for acid reflux may lead to an increased risk for fractures in children and adolescents, according to a study published online March 12 in the Journal of Pediatric Gastroenterology and... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 2, 2020 Category: Pharmaceuticals Source Type: news
Proton Pump Inhibitors and Dementia
Hospitals can be dangerous places for older adults. One of these dangers is inappropriate medications — the most common of which is proton pump inhibitors (PPIs). Patients who are discharged taking a PPI often continue to receive it after their admission to a skilled nursing facility. But care needs to be taken: if the PPI is inappropriate, it must be discontinued. As this article highlights, PPIs have many risks to be considered when assessing their continued use with long-term care patients. (Source: Caring for the Ages)
Source: Caring for the Ages - March 31, 2020 Category: Health Management Authors: Sanaz MoharramZadeh, Nader Tavakoli, Amrit Parhar Source Type: news
Fracture Risk Appears Higher With PPIs Than With H2RAs Fracture Risk Appears Higher With PPIs Than With H2RAs
Proton-pump inhibitors (PPIs) appear to carry a higher risk of bone fractures than histamine-2 receptor antagonists (H2RAs), according to two new studies, one in South Korean women and one in kidney-transplant recipients in the U.S.Reuters Health Information (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - March 30, 2020 Category: Orthopaedics Tags: Family Medicine/Primary Care News Source Type: news
The Effects of PPIs on the Microbiome of the Digestive Tract The Effects of PPIs on the Microbiome of the Digestive Tract
Using evidence from next-generation sequencing studies, this review examined the association of PPIs with alterations to gut microbiota. What are the implications of PPI-induced dysbiosis?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 30, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Proton Pump Inhibitors May Up Fracture Risk in Children
WEDNESDAY, March 25, 2020 -- Proton pump inhibitor (PPI) use in children is associated with a small but significant increased risk for any fracture, according to a study published online March 16 in JAMA Pediatrics.
Yun-Han Wang, from the Karolinska... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 25, 2020 Category: Pharmaceuticals Source Type: news
Use of PPIs Tied to Cognitive Issues in Breast Cancer Survivors
Concentration, memory problems reported in breast cancer patients at different stages of survivorship (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - March 3, 2020 Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Gynecology, Internal Medicine, Neurology, Oncology, Pharmacy, Journal, Source Type: news
Use of PPIs Tied to Cognitive Issues in Breast Cancer Survivors
TUESDAY, March 3, 2020 -- Use of acid reflux drugs (proton pump inhibitors [PPIs]) during and after cancer treatment may be tied to impaired memory and concentration in breast cancer survivors, according to a study recently published in the Journal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 3, 2020 Category: Pharmaceuticals Source Type: news
The Risks of Proton Pump Inhibitors During Pregnancy The Risks of Proton Pump Inhibitors During Pregnancy
Questions remain concerning the safety of PPI use during pregnancy. This meta-analysis assessed the risk of adverse neonatal outcomes associated with maternal intake of PPIs.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 2, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Could Heartburn Meds Lead to Drug-Resistant Germs?
The findings do not prove that PPIs -- which include popular brands such as Prilosec (omeprazole), Prevacid (lansoprazole) and Nexium (esomeprazole) -- are the cause, experts said.
But they are the latest to raise safety questions about the top-selling prescription and over-the-counter medicines. (Source: WebMD Health)
Source: WebMD Health - February 25, 2020 Category: Consumer Health News Source Type: news
GI-Bleeding Prophylaxis Benefits Higher-Risk Critically Ill Patients GI-Bleeding Prophylaxis Benefits Higher-Risk Critically Ill Patients
Prophylaxis with proton-pump inhibitors (PPIs) or histamine-2-receptor antagonists (H2RAs) significantly reduces gastrointestinal bleeding in higher-risk critically ill patients, but not in patients at low risk of bleeding, according to a systematic review and network meta-analysis.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - January 27, 2020 Category: Intensive Care Tags: Gastroenterology News Source Type: news
Ben-Gurion University researchers slash pre-drug screening time from years to days
(American Associates, Ben-Gurion University of the Negev) 'Our new approach will increase the understanding of the mechanisms and evolutionary origins of specific PPIs, and facilitate the rational design of specific inhibitors that can discriminate between structurally similar protein targets,' says Professor Niv Papo of BGU's Avram and Stella Goldstein-Goren Department of Biotechnology Engineering and the National Institute for Biotechnology in the Negev (NIBN). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 22, 2020 Category: Cancer & Oncology Source Type: news
Low-Value PPI Prescriptions Among Older Adults Low-Value PPI Prescriptions Among Older Adults
Older adults are particularly vulnerable to adverse events associated with PPIs. How prevalent is the prescribing of potentially low-value PPI prescriptions to adults 65 and older?Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 14, 2020 Category: Consumer Health News Tags: Internal Medicine Journal Article Source Type: news
Half of Patients on PPIs for GERD Still Have Persistent Symptoms
TUESDAY, Dec. 24, 2019 -- Gastroesophageal reflux disorder (GERD) symptoms are common, and more than half of patients taking daily proton pump inhibitor (PPI) therapy continue to experience persistent symptoms, according to a study published online... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 24, 2019 Category: Pharmaceuticals Source Type: news
Do PPIs Increase the Risk for Renal Damage or Mortality? Do PPIs Increase the Risk for Renal Damage or Mortality?
Dr Tejas Desai looks into the latest analysis on the potential adverse effects of proton pump inhibitors and asks whether de-escalation measures should be implemented.Medscape Nephrology (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - December 23, 2019 Category: Gastroenterology Tags: Nephrology Viewpoint Source Type: news
