More evidence links heartburn drugs to serious kidney problems
(Reuters Health) - People taking common heartburn medications known as proton pump inhibitors (PPIs) are at increased risk of new and severe kidney disease, according to a U.S. study. (Source: Reuters: Health)
Source: Reuters: Health - April 22, 2016 Category: Consumer Health News Tags: healthNews Source Type: news
PPIs associated with antibiotic-resistant bacteria carriage
AMSTERDAM – The long-term safety of proton pump inhibitors has once again come into question, as they may quadruple the chance of carrying a bacterial strain highly resistant to both penicillin and... (Source: Family Practice News)
Source: Family Practice News - April 21, 2016 Category: Primary Care Source Type: news
PPIs and Dementia: Is Causality Really There?
"Keep calm and carry on" suggests a thoughtful gastroenterologist whose patients continue to ask for reassurance. (Source: ConsultantLive)
Source: ConsultantLive - April 15, 2016 Category: Internal Medicine Authors: Fouad Moawad, MD Tags: Gastrointestinal Disorders Nervous System Diseases Source Type: news
Topical Steroids vs. PPIs for Eosinophilic EsophagitisTopical Steroids vs. PPIs for Eosinophilic Esophagitis
How do proton pump inhibitors measure up to topical steroids in the treatment of eosinophilic esophagitis? Alimentary Pharmacology & Therapeutics (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - April 15, 2016 Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news
PPIs and Kidney Injury: Longer Use Tied to Higher RiskPPIs and Kidney Injury: Longer Use Tied to Higher Risk
Proton pump inhibitors have been linked again to chronic kidney disease; the longer they are used, the greater the risk for adverse renal outcomes. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 14, 2016 Category: Consumer Health News Tags: Nephrology News Source Type: news
PPI cuts GI events from low- and high-dose aspirin
CHICAGO – Six months of treatment with a proton pump inhibitor (PPI) is a safe way to cut the incidence of major gastrointestinal events in cardiovascular disease patients on dual-antiplatelet... (Source: Family Practice News)
Source: Family Practice News - April 14, 2016 Category: Primary Care Source Type: news
Long-Term Proton Pump Inhibitor Use Associated With Increased Risk of Dementia
Long-term use of proton pump inhibitors was significantly associated with later diagnoses of dementia in adults 75 and older in a prospective cohort study of more than 73,000 individuals. The findings were published online in JAMA Neurology. (Source: Caring for the Ages)
Source: Caring for the Ages - March 30, 2016 Category: Health Management Authors: Heidi Splete Source Type: news
Your NEJM Group Today: Gray-Blue Skin Change; PPIs, NSAIDs, SSRIs & Colitis; California Internist Opportunity (FREE)
By the Editors
NEJM Group offers so many valuable resources for practicing clinicians. Here's what we chose for you today: NEJM Clinical Practice Center: Image in Clinical Medicine: … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 29, 2016 Category: Primary Care Source Type: news
PPIs May Lower GI Events After DAPT With Low-Dose Aspirin PPIs May Lower GI Events After DAPT With Low-Dose Aspirin
Based on new analysis from COGENT, "one could make an argument to consider routine PPIs" in these CAD patients, said the senior author. "But that does go beyond current guidelines." Heartwire from Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 29, 2016 Category: Cardiology Tags: Cardiology News Source Type: news
Proton Pump Inhibitor-responsive Esophageal EosinophiliaProton Pump Inhibitor-responsive Esophageal Eosinophilia
Are proton pump inhibitors the most effective therapy for all types of eosinophilic esophagitis regardless of histology? Gut (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 29, 2016 Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news
Proton pump inhibitors (PPIs) may come with worrying health effects
A mounting body of research suggests that pills taken by millions to relieve acid reflux come with their own worrying health effects. (Source: the Mail online | Health)
Source: the Mail online | Health - March 28, 2016 Category: Consumer Health News Source Type: news
What is the Recurrence Risk for Clostridium difficile Infection?
Discussion
Clostridium difficile infection (CDI) is a common cause of nosocomial diarrhea.
Clostridium difficile is an obligate, anaerobic, gram-positive bacillus that is spore-forming and toxin producing. It is resistant to acid, heat, antibiotics and many antiseptic agents. Spores are acquired from the environment or by oral-fecal route. Once in the colon, the bacteria attach and proliferate making vegetative forms. Two main toxins are produced which disrupt the colonic integrity. Toxin A (TcdA) is an endotoxin that disrupts the mucosal cells. Toxin B (TcdB) is a cytotoxin that is 1000x more potent than TcdA and causes...
Source: PediatricEducation.org - March 28, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
FDA Drug Safety Communication: Possible increased risk of fractures of the hip, wrist, and spine with the use of proton pump inhibitors
Update: 3/23/2011
FDA has determined an osteoporosis and fracture warning on the over-the-counter (OTC) proton pump inhibitor (PPI) medication “Drug Facts” label is not indicated at this time. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 23, 2016 Category: Drugs & Pharmacology Source Type: news
Can a heartburn drug cause cognitive problems?
A new study has shed light on one of the long-term effects of proton pump inhibitors (PPIs). These drugs are commonly used to treat gastroesophageal reflux disease (GERD), heartburn, and peptic ulcers. PPIs (omeprazole, lansoprazole, esomeprazole, pantoprazole, and others) help reduce the amount of stomach acid made by glands in the lining of the stomach.
Research published online on February 15 in JAMA Neurology showed that there may be an association between chronic use of PPIs and an increased risk of dementia. Experts compared prescription PPI intake and diagnosis of dementia among approximately 74,000 adults ages 75 a...
Source: New Harvard Health Information - March 21, 2016 Category: Consumer Health News Authors: Matthew Solan Tags: Brain and cognitive health Digestive Disorders Drugs and Supplements Healthy Aging Memory Mental Health heartburn PPIs proton pump inhibitors Source Type: news
