Propofol discovery may help lead to development of new anaesthetics
(Imperial College London) New research on the most commonly used anaesthetic drug could help to unravel a long-standing mystery about how it induces a pain-free, sleep-like state. Following years of research, scientists have identified exactly how propofol acts at a molecular level. Having a more detailed picture of exactly how it works in the brain may help scientists to design new versions that reduce the risks involved in surgery. Propofol was linked to the death of Michael Jackson. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 22, 2013 Category: Global & Universal Source Type: news

Doctor: Michael Jackson's pain was real
Before Michael Jackson asked a doctor to treat his insomnia with propofol, he tried falling asleep to the physician reading him bedtime stories. (Source: WDSU.com - Health)
Source: WDSU.com - Health - September 8, 2013 Category: Consumer Health News Source Type: news

Dexmedetomidine Use in the ICUDexmedetomidine Use in the ICU
Learn more about the efficacy of dexmedetomidine vs midazolam or propofol in maintaining sedation, reducing duration of mechanical ventilation, and improving patients' interaction. Critical Care (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 15, 2013 Category: Consumer Health News Tags: Critical Care Journal Article Source Type: news

Texas faces looming shortage of execution drug pentobarbital
Suppliers baulk at providing sedatives to the US state that executes more inmates than any otherTexas, the state with the highest execution rate in the US, is running out of a sedative used in its three-drug cocktail for lethal injections for the second time in 13 months, a state official said on Thursday.A spokesman for the Texas department of criminal justice, Jason Clark, confirmed that the state's supply of pentobarbital, which has been used in the execution of condemned killers in the state since July last year, will reach its expiry date in September.Texas switched to pentobarbital, a barbiturate that is the drug of ...
Source: Guardian Unlimited Science - August 2, 2013 Category: Science Tags: theguardian.com United States Capital punishment Texas Missouri News Drugs World news Source Type: news

Fresenius files patent infringements suit against DRL in US
Fresenius Kabi has dragged leading pharmaceuticals company Dr Reddy's to court for allegedly infringing on the former's patented anaesthetic Diprivan. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - May 26, 2013 Category: Pharmaceuticals Source Type: news

Consumer Information on: SEDASYS® Computer-Assisted Personalized Sedation System - P080009
The SEDASYS System is a computer-assisted personalized sedation device that delivers the drug propofol for minimal-to-moderate sedation. The device provides comprehensive patient monitoring and limits the depth of sedation by adjusting drug delivery accor (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - May 24, 2013 Category: Medical Equipment Source Type: news

Blood Loss During Endoscopic Sinus SurgeryBlood Loss During Endoscopic Sinus Surgery
Blood loss during endoscopic sinus surgery was similar for total intravenous anesthesia (TIVA) with propofol and for inhalational anesthesia with sevoflurane, in a randomized trial. Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 20, 2013 Category: Consumer Health News Tags: General Surgery News Source Type: news

New Combination Sedative Ketofol Safer for ChildrenNew Combination Sedative Ketofol Safer for Children
The newly-available combination of ketamine and propofol reduces adverse events in pediatric patients, report researchers. In another study, capnography during sedation led to fewer, but more appropriate interventions. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 15, 2013 Category: Consumer Health News Tags: Pediatrics News Source Type: news

SEDASYS Propofol Sedation System Gets FDA Nod
Ethicon Endo-Surgery, a Johnson & Johnson company, announced that the FDA granted PMA approval for its SEDASYS device, the first computer-assisted personalized sedation (CAPS) system for use by clinicians in the endoscopy suites.In other words, the system aims to replace anesthesiologists and CRNAs with computerized technology to administer propofol and to monitor minimal-to-moderate sedation in patients undergoing upper and lower endoscopies. According to the company, only ASA class I and II patients are eligible to receive propofol via SEDASYS.Read More (Source: Medgadget Anesthesiology)
Source: Medgadget Anesthesiology - May 10, 2013 Category: Anesthesiology Authors: Editors Tags: Anesthesiology GI Source Type: news

FDA Grants Premarket Approval (PMA) For The SEDASYS(R) System For Healthy Patients Undergoing Sedation During Routine Colonoscopy And EGD Procedures
Reduces risks associated with oversedation, facilitates faster patient recovery and increases physician satisfaction CINCINNATI, May 3, 2013 -- (Healthcare Sales & Marketing Network) -- Sedasys, a Division of Ethicon Endo-Surgery, Inc. (Ethicon), today... Devices, Drug Delivery, Gastroenterology, Oncology, FDASedasys, Ethicon Endo-Surgery, Propofol, Colonoscopy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 6, 2013 Category: Pharmaceuticals Source Type: news

More Health Care Professionals Abusing Anesthesia Drug
Those using propofol more likely to be women, depressed or have history of abuse, researchers say Source: HealthDay Related MedlinePlus Pages: Anesthesia, Prescription Drug Abuse (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 26, 2013 Category: Consumer Health News Source Type: news

Propofol Abuse Increasing In Health Care Setting
Abuse of common anesthetic has 'rapid downhill course,' reports Journal of Addiction Medicine Abuse of the anesthesia drug propofol is a "rapidly progressive form of substance dependence" that is being more commonly seen among health care professionals, reports a study in the April Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 20, 2013 Category: Consumer Health News Tags: Alcohol / Addiction / Illegal Drugs Source Type: news

Study shows rising rate of propofol abuse by health care professionals
(Wolters Kluwer Health) Abuse of the anesthesia drug propofol is a "rapidly progressive form of substance dependence" that is being more commonly seen among health care professionals, reports a study in the Apr. Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 18, 2013 Category: Global & Universal Source Type: news

Colonoscopy may be more risky under anesthesia
The risk for aspiration and other complications related to colonoscopy may be increased if the procedure is performed under propofol-induced deep sedation, US study findings suggest. (Source: MedWire News - Anesthesiology)
Source: MedWire News - Anesthesiology - March 15, 2013 Category: Anesthesiology Source Type: news