PHACE syndrome: a case report and a comprehensive review
CONCLUSION: PHACE syndrome, although being a rare occurrence, must be kept as a differential diagnosis in infants and children with facial hemangioma. Imaging modalities like MRI/magnetic resonance arteriography must be used to rule out possible associations related to PHACE syndrome and focus on early treatment to prevent possible complications.PMID:38576986 | PMC:PMC10990333 | DOI:10.1097/MS9.0000000000001759 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Munna William Amrit Bhusal Syed Muhammad Umar Ayesha Jamal Abdul Sattar Anjum Mudasira Habib Source Type: research
Propranolol use in patients with cirrhosis and refractory ascites: A nationwide study
Conclusions: Use of propanolol was associated with reduced mortality, compared with controls, in this nationwide cohort of patients with cirrhosis and refractory ascites. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 16, 2022 Category: Gastroenterology Authors: Yen-Chun Chen Yun-Da Li Chia-Ming Lu Wei-Chun Huang Sung-Shuo Kao Wen-Chi Chen Source Type: research
The role of propanolol in cardiomyocyte proliferation in tetralogy of Fallot – new market for an ‘old’ drug?
Tetralogy of Fallot (ToF) is one of the most common congenital heart defects and many patients have reached adulthood already. Since more than 50 years the beta-blocker propanolol is used in infants with unrepaired ToF to prevent life-threatening cyanotic spells and its positive clinical effect has been demonstrated in several studies [1–3]. The blockage of beta adrenergic receptors can reduce myocardial oxygen consumption and can affect myocardial cell hypertrophy but also seems to play a role in myocardial cell proliferation and division. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - August 5, 2021 Category: Cardiology Authors: Inga Voges, Sylvia Krupickova Tags: Editorial Source Type: research
GSE142061 Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and non-antibiotic pharmaceuticals stressed Acinetobacter baylyi ADP1 Transcriptomes
Contributors : Yue Wang ; Jianhua Guo ; Likai MaoSeries Type : Expression profiling by high throughput sequencingOrganism : Acinetobacter baylyiThe goals of this study are to use Next-generation sequencing (NGS) to detect bacterial mRNA profiles of wild-type A.baylyi ADP1, and its mRNA response under the exposure of six non-antibiotic pharmaceuticals, including ibuprofen, naproxen, gemfibrozil, diclofenac, propanolol, and iopromide. The concentrations were 0.5 mg/L for ibuprofen, naproxen, gemfibrozil, diclofenac, propanolol, and 1.0 mg/L for iopromide. The group without dosing pharmaceutical was the control group. Each...
Source: GEO: Gene Expression Omnibus - July 22, 2020 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Acinetobacter baylyi Source Type: research
Single-step pyrolysis for producing magnetic activated carbon from tucumã (Astrocaryum aculeatum) seed and nickel(II) chloride and zinc(II) chloride. Application for removal of nicotinamide and propanolol
Publication date: Available online 22 May 2020Source: Journal of Hazardous MaterialsAuthor(s): Pascal S. Thue, Cibele S. Umpierres, Eder C. Lima, Diana R. Lima, Fernando M. Machado, Glaydson S. dos Reis, Raphaelle S. da Silva, Flavio A. Pavan, Hai Nguyen Tran (Source: Journal of Hazardous Materials)
Source: Journal of Hazardous Materials - May 22, 2020 Category: Environmental Health Source Type: research
Propranolol for Surgeons in the Treatment of Infantile Hemangiomas
Conclusion:
Low dose propranolol and topical Timolol is been safe and easy to use for surgeons who may not be regular prescribers or unfamiliar with treating children with IHs with beta-blocker therapy. In patient monitoring is unnecessary and parents can be taught easily to recognise side effects. Treating children from the start builds a trusting relationship with the family before the child requesting cosmetic revision of the fibro-fatty remnant. (Source: Journal of Craniofacial Surgery)
Source: Journal of Craniofacial Surgery - December 27, 2019 Category: Surgery Tags: Original Articles Source Type: research
Objective evaluation of infantile hemangiomas response to propanolol treatment using a 3D imaging system.
This article is protected by copyright. All rights reserved.
PMID: 30919412 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 27, 2019 Category: Dermatology Authors: Moro R, Fabiano A, Mangeri F, Di Buduo A, Manerba A, Rossini M, Calzavara-Pinton PG, Gualdi G Tags: Br J Dermatol Source Type: research
Fetal supraventricular tachycardia at 12 weeks of gestation: diagnosis and follow up. A case report.
This report describes a case of fetal supraventricular tachycardia (SVT) diagnosed at 12 weeks of gestation in a pregnant woman with diabetes mellitus. Transplacental digoxin therapy administered orally to the mother was unsuccessful. Subsequently, sotalol was added to digoxin to achieve fetal heart rate (HR) control and the conversion to sinus rhythm was achieved. The fetal HR remained stable until term, and a healthy male baby was born. The newborn electrocardiogram showed sinus rhythm with normal PR and QTc intervals. When the newborn was stable, he was discharged with propanolol. Sustained SVT is extremely rare during ...
Source: Medical Ultrasonography - February 21, 2019 Category: Radiology Tags: Med Ultrason Source Type: research
Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1.
Abstract
Indoleamine 2,3 dioxygenase 1 (IDO1) is a metabolic enzyme that catalyzes the conversion of the essential amino acid tryptophan (Trp) into a series of immunoactive catabolites, collectively known as kynurenines. Through the depletion of Trp and the generation of kynurenines, IDO1 represents a key regulator of the immune responses involved in physiologic homeostasis as well as in neoplastic and autoimmune pathologies. The IDO1 enzyme has been described as an important immune checkpoint to be targeted by catalytic inhibitors in the treatment of cancer. In contrast, a defective expression/activity of...
Source: Biochemical Pharmacology - October 31, 2018 Category: Drugs & Pharmacology Authors: Albini E, Coletti A, Greco F, Pallotta MT, Mondanelli G, Gargaro M, Belladonna ML, Volpi C, Bianchi R, Grohmann U, Macchiarulo A, Orabona C Tags: Biochem Pharmacol Source Type: research
Interdisciplinary Management of Head and Neck Vascular Anomalies: Clinical Presentation, Diagnostic Findings and Minimalinvasive Therapies
ConclusionsThis review provides knowledge on the current ISSVA classification of vascular anomalies, their clinical presentation, diagnostic evaluation and minimally invasive therapy options to encourage the establishment of a comprehensive interdisciplinary management for head and neck vascular anomalies. (Source: European Journal of Radiology Open)
Source: European Journal of Radiology Open - July 10, 2018 Category: Radiology Source Type: research
Effect of propranolol on heart rate variability in hyperthyroidism
We aimed to determine the effect of propanolol on heart rate variability (HRV) in hyperthyroidism before antithyroid treatment. This was a before and after study, on ten patients presenting overt hyperthyroidi... (Source: BMC Research Notes)
Source: BMC Research Notes - February 22, 2018 Category: Research Authors: Aurel T. Tankeu, Marcel Azabji-Kenfack, Chris-Nad ège Nganou, Eliane Ngassam, Liliane Kuate-Mfeukeu, Camille Mba, Mesmin Y. Dehayem, Jean-Claude Mbanya and Eugene Sobngwi Tags: Research note Source Type: research
Propranolol May Help Patients With PTSD
While exposure therapy is recognized as one of the best strategies for treating patients with posttraumatic stress disorder (PTSD), many continue to experience significant problems. Astudy published inAJP in Advance suggests that patients with PTSD who take propranolol (a noradrenergic beta-receptor blocker) prior to recalling their traumatic event may experience greater PTSD symptom reduction than those who do not take the medication.“PTSD participants who actively recalled their traumatic event under the influence of propranolol once a week for up to six weeks showed a substantial decrease in symptom ratings compared w...
Source: Psychiatr News - January 16, 2018 Category: Psychiatry Tags: ajp in advance post-traumatic stress disorder propanolol PTSD trauma reactivation therapy Source Type: research
