Opioid-related deaths between 2019 and 2021 across 9 Canadian provinces and territories
CMAJ. 2024 Apr 14;196(14):E469-E476. doi: 10.1503/cmaj.231339.ABSTRACTBACKGROUND: The drug toxicity crisis continues to accelerate across Canada, with rapid increases in opioid-related harms following the onset of the COVID-19 pandemic. We sought to describe trends in the burden of opioid-related deaths across Canada throughout the pandemic, comparing these trends by province or territory, age, and sex.METHODS: We conducted a repeated cross-sectional analysis of accidental opioid-related deaths between Jan. 1, 2019, and Dec. 31, 2021, across 9 Canadian provinces and territories using aggregated national data. Our primary m...
Source: cmaj - April 15, 2024 Category: General Medicine Authors: Shaleesa Ledlie David N Juurlink Mina Tadrous Muhammad Mamdani J Michael Paterson Tara Gomes Source Type: research
Opioid-related deaths between 2019 and 2021 across 9 Canadian provinces and territories
CMAJ. 2024 Apr 14;196(14):E469-E476. doi: 10.1503/cmaj.231339.ABSTRACTBACKGROUND: The drug toxicity crisis continues to accelerate across Canada, with rapid increases in opioid-related harms following the onset of the COVID-19 pandemic. We sought to describe trends in the burden of opioid-related deaths across Canada throughout the pandemic, comparing these trends by province or territory, age, and sex.METHODS: We conducted a repeated cross-sectional analysis of accidental opioid-related deaths between Jan. 1, 2019, and Dec. 31, 2021, across 9 Canadian provinces and territories using aggregated national data. Our primary m...
Source: Canadian Medical Association Journal - April 15, 2024 Category: General Medicine Authors: Shaleesa Ledlie David N Juurlink Mina Tadrous Muhammad Mamdani J Michael Paterson Tara Gomes Source Type: research
Opioid-related deaths between 2019 and 2021 across 9 Canadian provinces and territories
CMAJ. 2024 Apr 14;196(14):E469-E476. doi: 10.1503/cmaj.231339.ABSTRACTBACKGROUND: The drug toxicity crisis continues to accelerate across Canada, with rapid increases in opioid-related harms following the onset of the COVID-19 pandemic. We sought to describe trends in the burden of opioid-related deaths across Canada throughout the pandemic, comparing these trends by province or territory, age, and sex.METHODS: We conducted a repeated cross-sectional analysis of accidental opioid-related deaths between Jan. 1, 2019, and Dec. 31, 2021, across 9 Canadian provinces and territories using aggregated national data. Our primary m...
Source: cmaj - April 15, 2024 Category: General Medicine Authors: Shaleesa Ledlie David N Juurlink Mina Tadrous Muhammad Mamdani J Michael Paterson Tara Gomes Source Type: research
Opioid-related deaths between 2019 and 2021 across 9 Canadian provinces and territories
CMAJ. 2024 Apr 14;196(14):E469-E476. doi: 10.1503/cmaj.231339.ABSTRACTBACKGROUND: The drug toxicity crisis continues to accelerate across Canada, with rapid increases in opioid-related harms following the onset of the COVID-19 pandemic. We sought to describe trends in the burden of opioid-related deaths across Canada throughout the pandemic, comparing these trends by province or territory, age, and sex.METHODS: We conducted a repeated cross-sectional analysis of accidental opioid-related deaths between Jan. 1, 2019, and Dec. 31, 2021, across 9 Canadian provinces and territories using aggregated national data. Our primary m...
Source: Canadian Medical Association Journal - April 15, 2024 Category: General Medicine Authors: Shaleesa Ledlie David N Juurlink Mina Tadrous Muhammad Mamdani J Michael Paterson Tara Gomes Source Type: research
The forecasting power of the mucin-microbiome interplay in livestock respiratory diseases
Vet Q. 2024 Dec;44(1):1-18. doi: 10.1080/01652176.2024.2340003. Epub 2024 Apr 12.ABSTRACTComplex respiratory diseases are a significant challenge for the livestock industry worldwide. These diseases considerably impact animal health and welfare and cause severe economic losses. One of the first lines of pathogen defense combines the respiratory tract mucus, a highly viscous material primarily composed of mucins, and a thriving multi-kingdom microbial ecosystem. The microbiome-mucin interplay protects from unwanted substances and organisms, but its dysfunction may enable pathogenic infections and the onset of respiratory di...
Source: Veterinary Quarterly - April 12, 2024 Category: Veterinary Research Authors: N úria Mach Source Type: research
The forecasting power of the mucin-microbiome interplay in livestock respiratory diseases
Vet Q. 2024 Dec;44(1):1-18. doi: 10.1080/01652176.2024.2340003. Epub 2024 Apr 12.ABSTRACTComplex respiratory diseases are a significant challenge for the livestock industry worldwide. These diseases considerably impact animal health and welfare and cause severe economic losses. One of the first lines of pathogen defense combines the respiratory tract mucus, a highly viscous material primarily composed of mucins, and a thriving multi-kingdom microbial ecosystem. The microbiome-mucin interplay protects from unwanted substances and organisms, but its dysfunction may enable pathogenic infections and the onset of respiratory di...
Source: Veterinary Quarterly - April 12, 2024 Category: Veterinary Research Authors: N úria Mach Source Type: research
Injury in Starting and Replacement Players from Five Professional Men ’s Rugby Unions
ConclusionThis study demonstrated a lower injury incidence in replacement players compared with starters in the second half of matches, with a higher injury burden for replacement players due to higher mean injury severity. (Source: Sports Medicine)
Source: Sports Medicine - April 12, 2024 Category: Sports Medicine Source Type: research
Effects of perceptions of forest change and intergroup competition on community-based conservation behaviors
Conserv Biol. 2024 Apr 4:e14259. doi: 10.1111/cobi.14259. Online ahead of print.ABSTRACTApproximately one quarter of the earth's population directly harvests natural resources to meet their daily needs. These individuals are disproportionately required to alter their behaviors in response to increasing climatic variability and global biodiversity loss. Much of the ever-ambitious global conservation agenda relies on the voluntary uptake of conservation behaviors in such populations. Thus, it is critical to understand how such individuals perceive environmental change and use conservation practices as a tool to protect their...
Source: Conservation Biology - April 4, 2024 Category: Biology Authors: Matt Clark Haji Masoud Hamad Jeffrey Andrews Vicken Hillis Monique Borgerhoff Mulder Source Type: research
Effects of perceptions of forest change and intergroup competition on community-based conservation behaviors
Conserv Biol. 2024 Apr 4:e14259. doi: 10.1111/cobi.14259. Online ahead of print.ABSTRACTApproximately one quarter of the earth's population directly harvests natural resources to meet their daily needs. These individuals are disproportionately required to alter their behaviors in response to increasing climatic variability and global biodiversity loss. Much of the ever-ambitious global conservation agenda relies on the voluntary uptake of conservation behaviors in such populations. Thus, it is critical to understand how such individuals perceive environmental change and use conservation practices as a tool to protect their...
Source: Conservation Biology - April 4, 2024 Category: Biology Authors: Matt Clark Haji Masoud Hamad Jeffrey Andrews Vicken Hillis Monique Borgerhoff Mulder Source Type: research
Exploring the association between weight loss-inducing medications and multiple sclerosis: insights from the FDA adverse event reporting system database
CONCLUSION: Our findings suggest a potential consideration for repurposing anti-diabetic weight loss-inducing drugs including semaglutide, dulaglutide, and liraglutide (glucagon-like peptide-1 receptor agonists), empagliflozin (sodium-glucose cotransporter-2 inhibitor), and metformin (biguanide), for MS. This warrants validation through rigorous methodologies and prospective studies.PMID:38566910 | PMC:PMC10986166 | DOI:10.1177/17562864241241383 (Source: Adv Data)
Source: Adv Data - April 3, 2024 Category: Epidemiology Authors: Afsaneh Shirani Anne H Cross Olaf Stuve Source Type: research
An innovative low-cost breast pump-hire program to enhance breastfeeding rates in a neonatal intensive care unit
CONCLUSION: The findings suggested that the low-cost breast pump hire program supported equitable care, increasing women's ability to provide expressed breastmilk for their infants.IMPACT: Providing access to low-cost hospital-grade breast pumps to mothers of vulnerable infants is likely to prevent poor infant clinical outcomes and improve women's care satisfaction.PUBLIC OR PATIENT CONTRIBUTION: Nil.PMID:38558479 | DOI:10.1111/jan.16180 (Source: Adv Data)
Source: Adv Data - April 1, 2024 Category: Epidemiology Authors: Linda Sweet Jessica Hughes Asiyath Rasheed Vidanka Vasilevski Source Type: research
Structural and sequence analysis of the RPO30 gene of sheeppox and goatpox viruses from India
Vet Q. 2024 Dec;44(1):1-12. doi: 10.1080/01652176.2024.2331524. Epub 2024 Mar 25.ABSTRACTSheeppox and goatpox are transboundary viral diseases of sheep and goats that cause significant economic losses to small and marginal farmers worldwide, including India. Members of the genus Capripoxvirus (CaPV), namely Sheeppox virus (SPPV), Goatpox virus (GTPV), and Lumpy skin disease virus (LSDV), are antigenically similar, and species differentiation can only be accomplished using molecular approaches. The present study aimed to understand the molecular epidemiology and host specificity of SPPV and GTPV circulating in India through...
Source: Veterinary Quarterly - March 25, 2024 Category: Veterinary Research Authors: Gundallahalli Bayyappa Manjunatha Reddy Krishnappa Sumana Revanaiah Yogisharadhya Hosakote Venkatappa Mohan Vijaykumar Kolar Lavanya Basavarajappa Harlipura Chethankumar Nayakwadi Shivasharanappa Mani Saminathan Sajjanar Basavaraj Kuldeep Dhama Shivachand Source Type: research
