Antibiotics Not Associated with Shorter Duration or Reduced Severity of Acute Lower Respiratory Tract Infection
ConclusionsIn this large prospective study in the US primary and urgent care setting, antibiotics had no measurable impact on the severity or duration of cough due to acute LRTI. Patients had unrealistic expectations regarding the duration of LRTI and the effect of antibiotics which should be the target of antibiotic stewardship efforts. (Source: Journal of General Internal Medicine)
Source: Journal of General Internal Medicine - April 15, 2024 Category: Internal Medicine Source Type: research
Albuterol delivery via in-line intrapulmonary percussive ventilation superimposed on conventional mechanical ventilation in an adult lung model
Conclusions: Albuterol delivery via IPV/CMV was modulated by percussion frequency but not increased with increasing VT The delivery efficiency was not sufficiently high for clinical use, in part due to nebulizer retention and extrapulmonary deposition.PMID:38538009 | DOI:10.4187/respcare.11249 (Source: Respiratory Care)
Source: Respiratory Care - March 27, 2024 Category: Respiratory Medicine Authors: Takashi Karashima Yuka Mimura-Kimura Yusuke Mimura Source Type: research
Aerosol Delivery to Simulated Spontaneously Breathing Tracheostomized Adult Model With and Without Humidification
Conclusion: Aerosol delivery in-line VMN and JN with unheated humidification was affected by nebulizer placement, interface, and gas flow settings.PMID:38485144 | DOI:10.4187/respcare.11495 (Source: Respiratory Care)
Source: Respiratory Care - March 14, 2024 Category: Respiratory Medicine Authors: Fai AlBuainain Jie Li Source Type: research
The association of prehospital systemic corticosteroids with emergency department and in-hospital outcomes for patients with asthma exacerbations
CONCLUSIONS: Prehospital systemic corticosteroid administration was not associated with hospitalization or LOS in the overall cohort of asthma patients treated by EMS, though they had a lower probability of admission within Bayesian models. Improved outcomes were noted among subgroups of longer EMS encounters, documented wheezing, and receipt of albuterol.PMID:38456349 | DOI:10.1111/acem.14890 (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - March 8, 2024 Category: Emergency Medicine Authors: Sriram Ramgopal Vishal V Naik Sho Komukai Sylvia Owusu-Ansah Remle P Crowe Masashi Okubo Christian Martin-Gill Source Type: research
The association of prehospital systemic corticosteroids with emergency department and in-hospital outcomes for patients with asthma exacerbations
CONCLUSIONS: Prehospital systemic corticosteroid administration was not associated with hospitalization or LOS in the overall cohort of asthma patients treated by EMS, though they had a lower probability of admission within Bayesian models. Improved outcomes were noted among subgroups of longer EMS encounters, documented wheezing, and receipt of albuterol.PMID:38456349 | DOI:10.1111/acem.14890 (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - March 8, 2024 Category: Emergency Medicine Authors: Sriram Ramgopal Vishal V Naik Sho Komukai Sylvia Owusu-Ansah Remle P Crowe Masashi Okubo Christian Martin-Gill Source Type: research
The association of prehospital systemic corticosteroids with emergency department and in-hospital outcomes for patients with asthma exacerbations
CONCLUSIONS: Prehospital systemic corticosteroid administration was not associated with hospitalization or LOS in the overall cohort of asthma patients treated by EMS, though they had a lower probability of admission within Bayesian models. Improved outcomes were noted among subgroups of longer EMS encounters, documented wheezing, and receipt of albuterol.PMID:38456349 | DOI:10.1111/acem.14890 (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - March 8, 2024 Category: Emergency Medicine Authors: Sriram Ramgopal Vishal V Naik Sho Komukai Sylvia Owusu-Ansah Remle P Crowe Masashi Okubo Christian Martin-Gill Source Type: research
Vesicovaginal and vesicorectal fistula in a patient with systemic sclerosis: A case report
Key Clinical MessageThis case highlights the need for further research to explore a potential link between systemic sclerosis and fistula development, and the importance of raising awareness among clinicians about this possibility for timely appropriate management.AbstractThe primary diagnosis in this case is systemic sclerosis (scleroderma) in a 47-year-old female patient with various clinical manifestations, including vesicovaginal and vesicorectal fistulas. The medical interventions and diagnostic workup involved an electrocardiogram, cardiac echocardiogram, pulmonary function tests, beta blockers, aspirin, inhaled cort...
Source: Clinical Case Reports - February 22, 2024 Category: General Medicine Authors: Mohammad Quteineh,
Sajedah N. Obeid,
Khayry Al ‐Shami,
Hamdah Hanifa Tags: CASE REPORT Source Type: research
79-Year-Old Man With Massive Hemoptysis
A 79-year-old man with medical comorbidities notable for a 20-pack-year smoking history, squamous cell carcinoma (SCC), chronic kidney disease stage III, and hypothyroidism presented with hemoptysis. Home medications included aspirin, 81 mg daily, omeprazole, 10 mg twice daily, simvastatin, 20 mg daily, and albuterol nebulizers as needed for dyspnea. He estimated the volume of blood to be about a cup (approximately 200 mL) and described it as bright red with clots and associated with chest tightness. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - February 6, 2024 Category: Internal Medicine Authors: Danielle M. Shilling, Amy N. Montgomery, Regina M. Mackey Tags: Residents ’ Clinic Source Type: research
Efficacy of albuterol –budesonide asthma rescue inhaler in adults with moderate-to-severe asthma with exercise as a trigger: post-hoc sub-group analysis of MANDALA
Albuterol-budesonide 180/160 μg inhaler is FDA approved for as-needed treatment or prevention of bronchoconstriction and to reduce exacerbation risk in patients aged ≥18 years with asthma. In MANDALA (NCT03769090), as-needed albuterol-budesonide 180/160μg reduced severe exacerbation risk by 28% versus albuterol in symptomat ic patients ≥18 years with moderate-to-severe asthma on a wide variety of inhaled corticosteroid (ICS)-containing maintenance therapies. Exercise is a well-recognized trigger of asthma symptoms/deterioration. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Elliot Israel, Bradley Chipps, Richard Beasley, R. Panettieri, Sam Bardsley, Christy Cappelletti, Lynn Dunsire, Ileen Gilbert, Tim Harrison, Frank Trudo, Alberto Papi Source Type: research
Efficacy Of Ipratropium Bromide/Albuterol Compared To Home Metered-Dose Inhalers For Inpatient Management Of Asthmatics
Many patients with asthma require frequent inhaler treatments despite being admitted for non-respiratory causes. Given extensive use of ipratropium bromide/albuterol nebulizer (Duoneb), this study compares clinical outcomes between Duoneb and home Metered Dose Inhalers (MDIs) regimen. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Valerie Jaroenpuntaruk, Elizabeth Ender, Jamie Sturgill Source Type: research
Effect of twice daily inhaled albuterol on cardiopulmonary exercise outcomes, dynamic hyperinflation, and symptoms in secondhand tobacco-exposed persons with preserved spirometry and air trapping: a randomized controlled trial
In tobacco-exposed persons with preserved spirometry (active smoking or secondhand smoke [SHS] exposure), air trapping can identify a subset with worse symptoms and exercise capacity. The physiologic nature of... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - January 20, 2024 Category: Respiratory Medicine Authors: Siyang Zeng, Melissa Nishihama, Lemlem Weldemichael, Helen Lozier, Warren M. Gold and Mehrdad Arjomandi Tags: Research Source Type: research
Oral Albuterol Treatment in Three Pediatric Patients with Bradycardia: A Novel Therapy
We report three cases of pediatric patients referred for pacemaker implantation for different types of bradycardia, treated at our institution with oral albuterol with therapeutic results that avoided the need for surgical pacemaker implantation at that time. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - December 25, 2023 Category: Cardiology Source Type: research
Impact of a discharge prescription for dexamethasone on outcomes of children treated in the emergency department for acute asthma exacerbations
CONCLUSIONS: Prescription for an additional dexamethasone dose was not associated with reduced treatment failure or improved outcomes for children with acute asthma discharged from the ED. Single, ED-dose of dexamethasone prior to discharge may be sufficient for children with mild to moderate asthma exacerbations.PMID:38112414 | DOI:10.1080/02770903.2023.2294910 (Source: Journal of Asthma)
Source: Journal of Asthma - December 19, 2023 Category: Respiratory Medicine Authors: Melisa S Tanverdi Nidhya Navanandan Savannah Brackman Lorel Huber Jan Leonard Rakesh D Mistry Source Type: research
