Pharmacokinetics, Safety, and Tolerability of Vonoprazan ‐ or Esomeprazole‐Based Bismuth‐Containing Quadruple Therapy: A Phase 1, Double‐Blind, Parallel‐Group Study in Adults with Helicobacter pylori Infection in China
In conclusion, vonoprazan had no significant effect on plasma bismuth exposure compared with esomeprazole. (Source: Clinical Pharmacology in Drug Development)
Source: Clinical Pharmacology in Drug Development - July 14, 2023 Category: Drugs & Pharmacology Authors: Jia Miao, Chao Hu, Jie Tang, Wenyan Wang, Ying Wang, Ruoting Men, Li Yang, Liqun Gu, Naoki Yoshida, Richard Czerniak Tags: Original Article Source Type: research

Distal renal tubular acidosis as presenting manifestation of Wilson disease in a 11-year-old girl
AbstractA 11-year-old girl was referred to the pediatric nephrology services of our hospital for evaluation of vitamin-D-refractory rickets. She was born to second-degree consanguineous parents. On examination, she had wrist widening and bilateral genu varum. She had normal anion gap metabolic acidosis, hypokalemia, and hyperchloremia. The fractional excretion of bicarbonate was 3% and the urine anion gap was positive. She also had hypercalciuria, but no phosphaturia, glucosuria or aminoaciduria. In view of a family history of an elder sister having rigidity with cognitive and speech impairment, an ophthalmic evaluation by...
Source: CEN Case Reports - July 6, 2023 Category: Urology & Nephrology Source Type: research

Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements: A Randomized Controlled Trial
CONCLUSIONS: With similar plasma potassium increase, RBC potassium uptake and kaliuresis were higher after an acute load of potassium citrate as compared to potassium chloride alone or pretreatment with lisinopril.PMID:37382933 | DOI:10.2215/CJN.0000000000000228 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - June 29, 2023 Category: Urology & Nephrology Authors: Rosa D Wouda Martin Gritter Micky Karsten Erik H A Michels Tamar M Nieuweboer A H Jan Danser Martin H de Borst Ewout J Hoorn Joris I Rotmans Liffert Vogt Source Type: research

Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements: A Randomized Controlled Trial
CONCLUSIONS: With similar plasma potassium increase, RBC potassium uptake and kaliuresis were higher after an acute load of potassium citrate as compared to potassium chloride alone or pretreatment with lisinopril.PMID:37382933 | DOI:10.2215/CJN.0000000000000228 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - June 29, 2023 Category: Urology & Nephrology Authors: Rosa D Wouda Martin Gritter Micky Karsten Erik H A Michels Tamar M Nieuweboer A H Jan Danser Martin H de Borst Ewout J Hoorn Joris I Rotmans Liffert Vogt Source Type: research

Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements: A Randomized Controlled Trial
CONCLUSIONS: With similar plasma potassium increase, RBC potassium uptake and kaliuresis were higher after an acute load of potassium citrate as compared to potassium chloride alone or pretreatment with lisinopril.PMID:37382933 | DOI:10.2215/CJN.0000000000000228 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - June 29, 2023 Category: Urology & Nephrology Authors: Rosa D Wouda Martin Gritter Micky Karsten Erik H A Michels Tamar M Nieuweboer A H Jan Danser Martin H de Borst Ewout J Hoorn Joris I Rotmans Liffert Vogt Source Type: research

Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements: A Randomized Controlled Trial
CONCLUSIONS: With similar plasma potassium increase, RBC potassium uptake and kaliuresis were higher after an acute load of potassium citrate as compared to potassium chloride alone or pretreatment with lisinopril.PMID:37382933 | DOI:10.2215/CJN.0000000000000228 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - June 29, 2023 Category: Urology & Nephrology Authors: Rosa D Wouda Martin Gritter Micky Karsten Erik H A Michels Tamar M Nieuweboer A H Jan Danser Martin H de Borst Ewout J Hoorn Joris I Rotmans Liffert Vogt Source Type: research

Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements: A Randomized Controlled Trial
CONCLUSIONS: With similar plasma potassium increase, RBC potassium uptake and kaliuresis were higher after an acute load of potassium citrate as compared to potassium chloride alone or pretreatment with lisinopril.PMID:37382933 | DOI:10.2215/CJN.0000000000000228 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - June 29, 2023 Category: Urology & Nephrology Authors: Rosa D Wouda Martin Gritter Micky Karsten Erik H A Michels Tamar M Nieuweboer A H Jan Danser Martin H de Borst Ewout J Hoorn Joris I Rotmans Liffert Vogt Source Type: research

Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements: A Randomized Controlled Trial
CONCLUSIONS: With similar plasma potassium increase, RBC potassium uptake and kaliuresis were higher after an acute load of potassium citrate as compared to potassium chloride alone or pretreatment with lisinopril.PMID:37382933 | DOI:10.2215/CJN.0000000000000228 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - June 29, 2023 Category: Urology & Nephrology Authors: Rosa D Wouda Martin Gritter Micky Karsten Erik H A Michels Tamar M Nieuweboer A H Jan Danser Martin H de Borst Ewout J Hoorn Joris I Rotmans Liffert Vogt Source Type: research

Kidney Stones in Epileptic Children Receiving Ketogenic Diet: Frequency and Risk Factors
Conclusion Renal stone appears to be a common adverse effect of KD therapy. Although adequate hydration and potassium citrate treatment are effective in most patients, lithotripsy and surgery may be required in a minority of patients. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Neuropediatrics)
Source: Neuropediatrics - May 31, 2023 Category: Neurology Authors: G üzin, Yiğithan Y ılmaz, Ünsal Devrim, Fatma Din çel, Nida Ünalp, Aycan Tags: Original Research Article Source Type: research