The potential for current sodium and potassium production to support a global switch to the use of potassium-enriched salt: a desktop research study
CONCLUSIONS: Significant up-scaling of the production of potassium chloride and the capacity of companies able to manufacture potassium-enriched salt, as well as a robust business case for the switch to potassium chloride, would be required.PMID:38644629 | DOI:10.1017/S1368980024000922 (Source: Public Health Nutrition)
Source: Public Health Nutrition - April 22, 2024 Category: International Medicine & Public Health Authors: James Bullen Katrina Kissock Xuejun Yin Penjani Mkambula Kathy Trieu Bradley Hastings Bruce Neal Ellie Paige Source Type: research
Common food preservatives impose distinct selective pressures on Salmonella Typhimurium planktonic and biofilm populations
In conclusion, we showed that preservatives affect biofilm formation and bacterial growth in a compound specific manner. We showed trade-offs between biofilm formation and preservative tolerance, but no antibiotic cross-tolerance. This indicates that bacterial adaptation to continuous preservative exposure, is unlikely to affect food safety or contribute to antibiotic resistance.PMID:38637079 | DOI:10.1016/j.fm.2024.104517 (Source: Food Microbiology)
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Justin Abi Assaf Emma R Holden Eleftheria Trampari Mark A Webber Source Type: research
Depth-Specific Hypoxic Responses to Spreading Depolarizations in Gyrencephalic Swine Cortex Unveiled by Photoacoustic Imaging
AbstractSpreading depolarizations (SDs) are a marker of brain injury and have a causative effect on ischemic lesion progression. The hemodynamic responses elicited by SDs are contingent upon the metabolic integrity of the affected tissue, with vasoconstrictive reactions leading to pronounced hypoxia often indicating poor outcomes. The stratification of hemodynamic responses within different cortical layers remains poorly characterized. This pilot study sought to elucidate the depth-specific hemodynamic changes in response to SDs within the gray matter of the gyrencephalic swine brain. Employing a potassium chloride –indu...
Source: Translational Stroke Research - April 16, 2024 Category: Neurology Source Type: research
Use of unlicensed drugs in a Swiss Pediatric University Hospital and associated prescribing error rates - a retrospective observational study
CONCLUSIONS: Unlicensed drugs are frequently prescribed in this paediatric hospital setting in Switzerland. Around every tenth prescription is an unlicensed drug. Because unlicensed drugs showed a significantly higher rate of prescribing errors, licensed drugs are favourable in terms of medication safety and should be prescribed whenever possible. If no licensed drug is available, imported drugs should be favoured over formula drugs due to lower prescribing error rates. To increase medication safety in paediatrics in Switzerland, efforts are necessary to increase the number of suitable licensed drug formulations for paedia...
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Aylin Satir Miriam Pfiffner Christoph R Meier Angela Caduff Good Source Type: research
Use of unlicensed drugs in a Swiss Pediatric University Hospital and associated prescribing error rates - a retrospective observational study
CONCLUSIONS: Unlicensed drugs are frequently prescribed in this paediatric hospital setting in Switzerland. Around every tenth prescription is an unlicensed drug. Because unlicensed drugs showed a significantly higher rate of prescribing errors, licensed drugs are favourable in terms of medication safety and should be prescribed whenever possible. If no licensed drug is available, imported drugs should be favoured over formula drugs due to lower prescribing error rates. To increase medication safety in paediatrics in Switzerland, efforts are necessary to increase the number of suitable licensed drug formulations for paedia...
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Aylin Satir Miriam Pfiffner Christoph R Meier Angela Caduff Good Source Type: research
Use of unlicensed drugs in a Swiss Pediatric University Hospital and associated prescribing error rates - a retrospective observational study
CONCLUSIONS: Unlicensed drugs are frequently prescribed in this paediatric hospital setting in Switzerland. Around every tenth prescription is an unlicensed drug. Because unlicensed drugs showed a significantly higher rate of prescribing errors, licensed drugs are favourable in terms of medication safety and should be prescribed whenever possible. If no licensed drug is available, imported drugs should be favoured over formula drugs due to lower prescribing error rates. To increase medication safety in paediatrics in Switzerland, efforts are necessary to increase the number of suitable licensed drug formulations for paedia...
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Aylin Satir Miriam Pfiffner Christoph R Meier Angela Caduff Good Source Type: research
Exploring the therapeutic potential of pomegranate juice for uterine relaxation
CONCLUSION: Research suggests pomegranate juice's active ingredient may reduce uterine contractions and treat uterotonic disorders, potentially preventing preterm birth and dysmenorrhea. Further research is needed to determine its mechanism of action.TRIAL REGISTRATION: Code: AEC-013.PMID:38525817 | DOI:10.1080/17446651.2024.2334218 (Source: Expert Review of Endocrinology and Metabolism)
Source: Expert Review of Endocrinology and Metabolism - March 25, 2024 Category: Endocrinology Authors: Omar A M Al-Habib Lina N Adam Source Type: research
Functional and metabolomic analysis of urinary extracellular vesicles from juvenile mice with renal compensatory hypertrophy
This study suggests that uEVs contain bioactive components capable of inducing protective, anti-inflammatory, anti-fibrinolytic, and antioxidative effects in renal cells. These findings contribute to our understanding of uEVs' role in renal compensatory mechanisms after unilateral nephrectomy and may hold promise for future therapeutic interventions in renal diseases.PMID:38499276 | DOI:10.1016/j.bbadis.2024.167096 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - March 18, 2024 Category: Biochemistry Authors: Rasha Aly Sara Darwish Niharika Bala Areej Ebrahim Lawrence R Shoemaker Joel McCray Timothy J Garrett Abdel A Alli Source Type: research
Functional and metabolomic analysis of urinary extracellular vesicles from juvenile mice with renal compensatory hypertrophy
This study suggests that uEVs contain bioactive components capable of inducing protective, anti-inflammatory, anti-fibrinolytic, and antioxidative effects in renal cells. These findings contribute to our understanding of uEVs' role in renal compensatory mechanisms after unilateral nephrectomy and may hold promise for future therapeutic interventions in renal diseases.PMID:38499276 | DOI:10.1016/j.bbadis.2024.167096 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - March 18, 2024 Category: Biochemistry Authors: Rasha Aly Sara Darwish Niharika Bala Areej Ebrahim Lawrence R Shoemaker Joel McCray Timothy J Garrett Abdel A Alli Source Type: research
