Laparoscopic Nephrectomy Via the Retroperitoneal Approach for Autosomal Dominant Polycystic Kidney Disease After Renal Transplant: A Case Report
We report a case of laparoscopic nephrectomy via the retroperitoneal approach for autosomal dominant polycystic kidney disease after renal transplant. A 54-year-old male patient with end-stage renal failure because of autosomal dominant polycystic kidney disease underwent a living donor renal transplant and right nephrectomy via open surgery through a median abdominal incision 5 years previously. However, the left kidney gradually became enlarged. We performed laparoscopic left nephrectomy via the retroperitoneal approach. After dissecting the renal vessels, we performed cyst puncture and aspiration to decrease the kidney ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 21, 2024 Category: Transplant Surgery Authors: Kazuro Kikkawa Hiraku Yamamoto Yasuo Kohjimoto Isao Hara Source Type: research

Laparoscopic Nephrectomy Via the Retroperitoneal Approach for Autosomal Dominant Polycystic Kidney Disease After Renal Transplant: A Case Report
We report a case of laparoscopic nephrectomy via the retroperitoneal approach for autosomal dominant polycystic kidney disease after renal transplant. A 54-year-old male patient with end-stage renal failure because of autosomal dominant polycystic kidney disease underwent a living donor renal transplant and right nephrectomy via open surgery through a median abdominal incision 5 years previously. However, the left kidney gradually became enlarged. We performed laparoscopic left nephrectomy via the retroperitoneal approach. After dissecting the renal vessels, we performed cyst puncture and aspiration to decrease the kidney ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 21, 2024 Category: Transplant Surgery Authors: Kazuro Kikkawa Hiraku Yamamoto Yasuo Kohjimoto Isao Hara Source Type: research

Laparoscopic Nephrectomy Via the Retroperitoneal Approach for Autosomal Dominant Polycystic Kidney Disease After Renal Transplant: A Case Report
We report a case of laparoscopic nephrectomy via the retroperitoneal approach for autosomal dominant polycystic kidney disease after renal transplant. A 54-year-old male patient with end-stage renal failure because of autosomal dominant polycystic kidney disease underwent a living donor renal transplant and right nephrectomy via open surgery through a median abdominal incision 5 years previously. However, the left kidney gradually became enlarged. We performed laparoscopic left nephrectomy via the retroperitoneal approach. After dissecting the renal vessels, we performed cyst puncture and aspiration to decrease the kidney ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 21, 2024 Category: Transplant Surgery Authors: Kazuro Kikkawa Hiraku Yamamoto Yasuo Kohjimoto Isao Hara Source Type: research

Laparoscopic Nephrectomy Via the Retroperitoneal Approach for Autosomal Dominant Polycystic Kidney Disease After Renal Transplant: A Case Report
We report a case of laparoscopic nephrectomy via the retroperitoneal approach for autosomal dominant polycystic kidney disease after renal transplant. A 54-year-old male patient with end-stage renal failure because of autosomal dominant polycystic kidney disease underwent a living donor renal transplant and right nephrectomy via open surgery through a median abdominal incision 5 years previously. However, the left kidney gradually became enlarged. We performed laparoscopic left nephrectomy via the retroperitoneal approach. After dissecting the renal vessels, we performed cyst puncture and aspiration to decrease the kidney ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 21, 2024 Category: Transplant Surgery Authors: Kazuro Kikkawa Hiraku Yamamoto Yasuo Kohjimoto Isao Hara Source Type: research

Laparoscopic Nephrectomy Via the Retroperitoneal Approach for Autosomal Dominant Polycystic Kidney Disease After Renal Transplant: A Case Report
We report a case of laparoscopic nephrectomy via the retroperitoneal approach for autosomal dominant polycystic kidney disease after renal transplant. A 54-year-old male patient with end-stage renal failure because of autosomal dominant polycystic kidney disease underwent a living donor renal transplant and right nephrectomy via open surgery through a median abdominal incision 5 years previously. However, the left kidney gradually became enlarged. We performed laparoscopic left nephrectomy via the retroperitoneal approach. After dissecting the renal vessels, we performed cyst puncture and aspiration to decrease the kidney ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 21, 2024 Category: Transplant Surgery Authors: Kazuro Kikkawa Hiraku Yamamoto Yasuo Kohjimoto Isao Hara Source Type: research

Laparoscopic Nephrectomy Via the Retroperitoneal Approach for Autosomal Dominant Polycystic Kidney Disease After Renal Transplant: A Case Report
We report a case of laparoscopic nephrectomy via the retroperitoneal approach for autosomal dominant polycystic kidney disease after renal transplant. A 54-year-old male patient with end-stage renal failure because of autosomal dominant polycystic kidney disease underwent a living donor renal transplant and right nephrectomy via open surgery through a median abdominal incision 5 years previously. However, the left kidney gradually became enlarged. We performed laparoscopic left nephrectomy via the retroperitoneal approach. After dissecting the renal vessels, we performed cyst puncture and aspiration to decrease the kidney ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 21, 2024 Category: Transplant Surgery Authors: Kazuro Kikkawa Hiraku Yamamoto Yasuo Kohjimoto Isao Hara Source Type: research

Laparoscopic Nephrectomy Via the Retroperitoneal Approach for Autosomal Dominant Polycystic Kidney Disease After Renal Transplant: A Case Report
We report a case of laparoscopic nephrectomy via the retroperitoneal approach for autosomal dominant polycystic kidney disease after renal transplant. A 54-year-old male patient with end-stage renal failure because of autosomal dominant polycystic kidney disease underwent a living donor renal transplant and right nephrectomy via open surgery through a median abdominal incision 5 years previously. However, the left kidney gradually became enlarged. We performed laparoscopic left nephrectomy via the retroperitoneal approach. After dissecting the renal vessels, we performed cyst puncture and aspiration to decrease the kidney ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 21, 2024 Category: Transplant Surgery Authors: Kazuro Kikkawa Hiraku Yamamoto Yasuo Kohjimoto Isao Hara Source Type: research

Laparoscopic Nephrectomy Via the Retroperitoneal Approach for Autosomal Dominant Polycystic Kidney Disease After Renal Transplant: A Case Report
We report a case of laparoscopic nephrectomy via the retroperitoneal approach for autosomal dominant polycystic kidney disease after renal transplant. A 54-year-old male patient with end-stage renal failure because of autosomal dominant polycystic kidney disease underwent a living donor renal transplant and right nephrectomy via open surgery through a median abdominal incision 5 years previously. However, the left kidney gradually became enlarged. We performed laparoscopic left nephrectomy via the retroperitoneal approach. After dissecting the renal vessels, we performed cyst puncture and aspiration to decrease the kidney ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 21, 2024 Category: Transplant Surgery Authors: Kazuro Kikkawa Hiraku Yamamoto Yasuo Kohjimoto Isao Hara Source Type: research

Laparoscopic Nephrectomy Via the Retroperitoneal Approach for Autosomal Dominant Polycystic Kidney Disease After Renal Transplant: A Case Report
We report a case of laparoscopic nephrectomy via the retroperitoneal approach for autosomal dominant polycystic kidney disease after renal transplant. A 54-year-old male patient with end-stage renal failure because of autosomal dominant polycystic kidney disease underwent a living donor renal transplant and right nephrectomy via open surgery through a median abdominal incision 5 years previously. However, the left kidney gradually became enlarged. We performed laparoscopic left nephrectomy via the retroperitoneal approach. After dissecting the renal vessels, we performed cyst puncture and aspiration to decrease the kidney ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - March 21, 2024 Category: Transplant Surgery Authors: Kazuro Kikkawa Hiraku Yamamoto Yasuo Kohjimoto Isao Hara Source Type: research

Ultrasound features of a bilineal inheritance of autosomal dominant polycystic kidney disease
We report a case of a nulliparous woman referred to our clinic at 29  weeks of gestation because of the finding of fetal increased hyperechoic kidneys. The partner was affected by ADPKD with a familiar history of the same disease (his grandfather, brother and father, who underwent kidney transplantation at 40 years of age). The first-trimester aneuploidies combin ed screening showed a high risk for trisomy 21 while the chorionic villus sampling detected a normal female karyotype. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 19, 2024 Category: OBGYN Authors: Elisa Montaguti, Francesca Montanari, Vito Bernardi, Elena Luppi, Pierandrea De Benedetti, Giulia Lanzoni, Marco Seri, Gianluigi Pilu Tags: Correspondance Source Type: research

Additional renoprotective effect of the SGLT2 inhibitor dapagliflozin in a patient with ADPKD receiving tolvaptan treatment
AbstractAutosomal dominant polycystic kidney disease (ADPKD) is a major cause of end-stage kidney disease (ESKD). Vasopressin plays a pivotal role in ADPKD progression; therefore, the selective vasopressin V2 receptor antagonist tolvaptan is used as a key drug in the management of ADPKD. On the other hand, sodium –glucose cotransporter-2 inhibitors (SGLT2i), which may possibly stimulate vasopressin secretion due to the diuretic effect of the drug, have been shown to have both renal and cardioprotective effects in various populations, including those with non-diabetic chronic kidney disease. However, the ef fect of SGLT2i...
Source: CEN Case Reports - March 18, 2024 Category: Urology & Nephrology Source Type: research

Ocular manifestations of renal ciliopathies
AbstractRenal ciliopathies are a common cause of kidney failure in children and adults, and this study reviewed their ocular associations. Genes affected in renal ciliopathies were identified from the Genomics England Panels. Ocular associations were identified from Medline and OMIM, and the genes additionally examined for expression in the human retina (https://www.proteinatlas.org/humanproteome/tissue) and for an ocular phenotype in mouse models (http://www.informatics.jax.org/). Eighty-two of the 86 pediatric-onset renal ciliopathies (95%) have an ocular phenotype, including inherited retinal degeneration, oculomotor di...
Source: Pediatric Nephrology - March 15, 2024 Category: Urology & Nephrology Source Type: research

Characteristics and clinical outcomes of patients with kidney failure of unknown aetiology from ANZDATA registry
This study included 60,448 people on dialysis and 20,859 transplant recipients. 1-year, 3-year and 5-year mortality rates in people with uESKD on dialysis were 31.6%, 58.7% and 77.2%, respectively. 1-year, 3-year and 5-year mortality rates in transplant recipients with uESKD were 2.8%, 13.8% and 24.0%, respectively. People with uESKD on dialysis had a higher mortality risk compared to those without uESKD on univariable and multivariable analyses (adjusted hazard ratio [AHR] 1.10, 95% CI 1.06 –1.16, p (Source: PLoS One)
Source: PLoS One - March 11, 2024 Category: Biomedical Science Authors: Lucy S. Wang Source Type: research

miRNAs Role in Wilms tumor pathogenesis: Signaling pathways interplay
Pathol Res Pract. 2024 Mar 5;256:155254. doi: 10.1016/j.prp.2024.155254. Online ahead of print.ABSTRACTWilms' tumors (WTs) are the most common type of kidney tumor in children, and a negative outlook is generally associated with widespread anaplastic. MicroRNAs (miRNAs) are crucial in the development of WT by regulating the expression of specific genes. There is an increasing amount of research that connects the dysregulation of miRNAs to the development of various renal illnesses. The conditions encompassed are renal fibrosis, renal cancers, and chronic and polycystic kidney disease. Dysregulation of several important miR...
Source: Pathology, Research and Practice - March 9, 2024 Category: Pathology Authors: Jaber Alfaifi Source Type: research

Tolvaptan Treatment and Long-Term Impact on Quality of Life in Autosomal Dominant Polycystic Kidney Disease Patients: A Pilot Study
(Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - March 2, 2024 Category: Drugs & Pharmacology Source Type: research