A Case of Persistent Lung Masses After Treatment of Hodgkin Lymphoma
Chest. 2024 Mar;165(3):e79-e84. doi: 10.1016/j.chest.2023.11.010.ABSTRACTThe patient is a 49-year-old woman who had never used tobacco with a history of relapsing polychondritis and episcleritis. She sought treatment at our clinic for evaluation of multiple lung masses. She originally received a diagnosis by chest radiography performed to rule out sarcoidosis as the cause of episcleritis showing an abnormal findings. She had no contributory surgical, family, or social history. The autoimmune markers were notable for positive rheumatoid factor (153 IU/mL) and elevated erythrocyte sedimentation rate (97 mm/h) and C-reactive ...
Source: Chest - March 9, 2024 Category: Respiratory Medicine Authors: Tejas Sinha Jian Fu Ashish Bains Andrew Gangemi Source Type: research
An Autopsy Case of COVID-19 with New Diffuse Pulmonary Ossification
We present the case of a 61-year-old man who developed Coronavirus disease 2019 (COVID-19) and died during treatment for relapsing polychondritis. The patient was intubated and treated with steroid pulse therapy, remdecivir, antibacterial agents, baricitinib, and tocilizumab. However, his respiratory condition worsened, and he died 108 days after disease onset. An autopsy revealed diffuse alveolar damage in the fibrotic phase in all lung lobes, diffuse pulmonary ossification, and cytomegalovirus-infected cells in the middle lobe of the right lung. We herein discuss the clinical features and pathological findings of COVID-1...
Source: Internal Medicine - March 3, 2024 Category: Internal Medicine Authors: Taisuke Nakagawa Yasuaki Kotetsu Katsumi Takizawa Michihiro Yoshimi Isamu Okamoto Shohei Takata Source Type: research
Unusual cause of the left main bronchus stenosis: relapsing polychondritis
AbstractRelapsing polychondritis is a rare disease that causes inflammation and destruction of cartilage and connective tissue. It can be associated with other autoimmune rheumatologic and hematologic diseases. Herein, we report a 38-year-old male patient with relapsing polychondritis and diffuse stenosis of the left main bronchus. (Source: Indian Journal of Thoracic and Cardiovascular Surgery)
Source: Indian Journal of Thoracic and Cardiovascular Surgery - March 1, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research
Bilateral medial rectus muscle infiltration secondary to relapsing polychondritis
J Fr Ophtalmol. 2024 Feb 15;47(3):104050. doi: 10.1016/j.jfo.2023.104050. Online ahead of print.NO ABSTRACTPMID:38364732 | DOI:10.1016/j.jfo.2023.104050 (Source: Journal Francais d Ophtalmologie)
Source: Journal Francais d Ophtalmologie - February 16, 2024 Category: Opthalmology Authors: T Didier B Laure Source Type: research
Risk factors associated with severe adverse events in patients with relapsing polychondritis undergoing flexible bronchoscopy
This study aimed... (Source: Orphanet Journal of Rare Diseases)
Source: Orphanet Journal of Rare Diseases - February 9, 2024 Category: Internal Medicine Authors: Shao-Ting Wang, Jinglan Wang, Xiaoxing Gao, Keqi Chen, Kai-Feng Xu and Xinlun Tian Tags: Research Source Type: research
Superior Orbital Fissure Syndrome in the Setting of Relapsing Polychondritis with Concurrent Sjogren's Syndrome: A Case Report
CONCLUSION: This case is notable for the rare coexistence of SOFS with RP/SS overlap syndrome and highlights the management of concurrent orbital inflammatory syndrome and autoimmune diseases.PMID:38324402 | DOI:10.1080/09273948.2024.2307405 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 7, 2024 Category: Allergy & Immunology Authors: Vishnusai Karri Abdullah Abou-Samra Brian King Adam Carlson Arthi Venkat Source Type: research
Relapsing Polychondritis with Tracheobronchial Involvement: A
Detailed Description of Two Pediatric Cases and Review of the
Literature
Klin Padiatr DOI: 10.1055/a-2230-1521Relapsing polychondritis (RP) is a rare immune-mediated disease that primarily
affects the cartilaginous structures of the ears, nose and airways. The clinical
spectrum ranges from mild to severe disease characterized by progressive
destruction of cartilage in the tracheobronchial tree leading to airway
obstruction and acute respiratory failure. Early diagnosis is crucial to prevent
irreversible airway damage and life-threatening complications. Due to its rarity
and variability of symptoms, the diagnosis of RP is often delayed ...
Source: Klinische Padiatrie - January 15, 2024 Category: Pediatrics Authors: Winter, Greta L öffelmann, Tara Chaya, Shaakira Kaiser, Hannah Prenzler, Nils Kristian Warnecke, Athanasia Wetzke, Martin Derlin, Thorsten Renz, Diane Stueber, Thomas L änger, Florian Sch ütz, Katharina Schwerk, Nicolaus Tags: Review Source Type: research
Successful Response to Golimumab in a Case of Relapsing Polychondritis Overlapping with Ulcerative Colitis
(Source: Biologics: Targets and Therapy)
Source: Biologics: Targets and Therapy - January 12, 2024 Category: Biochemistry Tags: Biologics: Targets and Therapy Source Type: research
Ultra-rare genetic variation in relapsing polychondritis: a whole-exome sequencing study
Conclusions
This study identified specific rare variants in the DCBLD2 gene as a putative genetic risk factor for RP. These findings should be validated in additional patients with RP and supported by future functional experiments. (Source: Annals of the Rheumatic Diseases)
Source: Annals of the Rheumatic Diseases - January 11, 2024 Category: Rheumatology Authors: Luo, Y., Ferrada, M. A., Sikora, K. A., Rankin, C., Alessi, H. D., Kastner, D. L., Deng, Z., Zhang, M., Merkel, P. A., Kraus, V. B., Allen, A. S., Grayson, P. C. Tags: ARD, Miscellaneous Source Type: research
