Nature's Take: Can Registered Reports help tackle publication bias?
Many researchers have been critical of the biases that the publication process can introduce into science. For example, they argue that a focus on publishing interesting or significant results can give a false impression of what broader research is finding about a particular field.To tackle this, some scientists have championed the publication of Registered Reports. These articles split the peer review process in two, first critically assessing the methodology of a research study before data is collected, and again when the results are found. The idea being to encourage robust research regardless of the outcome.In this epi...
Source: Nature Podcast - May 12, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

‘Pangenome’ aims to capture the breadth of human diversity
In this episode:00:45 Making a more diverse human genomeThe first draft of the human genome ushered in a new era of genetics research. Since its publication, researchers have constructed ever more accurate ‘reference genomes’ – baselines against which others are compared. But these are based on the DNA of a small number of people, and don’t represent the genetic variation known to exist across human populations. To address this, a consortium of researchers have published the first draft of a ‘pangenome’, which combines the genomes of 47 genetically diverse individuals. This draft provides a more complete pictur...
Source: Nature Podcast - May 10, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Menopause and women ’s health: why science needs to catch up
In this episode:00:47 A focus on women’s healthNature’s Kerri Smith and Heidi Ledford join us to discuss two Features published in Nature looking at topics surrounding women’s health. The first looks at efforts to understand how menopause affects brain health, while the second takes a deep-dive into research funding and shows how conditions affecting women more than men receive less money.Feature: How menopause reshapes the brainFeature: Women’s health research lacks funding – these charts show how18:15 Research HighlightsThe herb that could be a new source of cannabinoid compounds, and the vibrating crystal that...
Source: Nature Podcast - May 3, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Audio long read: Conquering Alzheimer ’s — a look at the therapies of the future
Last year, researchers announced that the Alzheimer’s drug lecanemab lowered the amount of amyloid protein plaques associated with the disease in the brains of participants in a clinical trial, and slowed their cognitive decline.Now, researchers are looking to drug combinations, vaccines and gene therapy to tackle different stages of the disease, as they forge the next generation of treatments for the condition.This is an audio version of our Feature: Conquering Alzheimer’s: a look at the therapies of the future Hosted on Acast. See acast.com/privacy for more information. (Source: Nature Podcast)
Source: Nature Podcast - April 28, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

How Rosalind Franklin ’s story was rewritten
In this episode:00:57 Franklin’s real roleWhen it comes to the structure of DNA, everyone thinks they know Rosalind Franklin’s role in its discovery. The story goes that her crucial data was taken by James Watson without her knowledge, helping him and Francis Crick solve the structure. However, new evidence has revealed that this wasn’t really the case. Rosalind Franklin was not a ‘wronged heroine’, she was an equal contributor to the discovery.Comment: What Rosalind Franklin truly contributed to the discovery of DNA’s structure13:41 Research HighlightsHow the growth of tiny iodine-engined satellites could dama...
Source: Nature Podcast - April 26, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

A smarter way to melt down plastics?
In this episode:00:45 A new method to break down plastic polymersPlastic waste is an enormous problem, with much of it being incinerated or ending up in landfill. One way to give plastics another life is to break them down into their individual components using heat, but this method yields low amounts of usable product. Now, a team demonstrates a proof-of-concept method of heating that wicks the plastic like a candle through a layer of carbon material. They show that this method is more efficient and could be an additional way of breaking down waste plastics.Research article: Dong et al.08:48 Research HighlightsPhysicists ...
Source: Nature Podcast - April 19, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

How to battle misinformation with Sander van der Linden
In the latest episode of Nature hits the books, psychologist Sander van der Linden joins us to discuss his new book Foolproof, which focuses on misinformation and what can be done to prevent people being duped, particularly by the falsehoods found online.We discuss how misinformation messages are crafted, why they can be hard to shake once someone is exposed, and how Star Wars: Episode 3 helped in the fight against them…Foolproof, Sander van der Linden, Fourth Estate (2023)Music supplied by Airae/Epidemic Sound/Getty images. Hosted on Acast. See acast.com/privacy for more information. (Source: Nature Podcast)
Source: Nature Podcast - April 14, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Octopuses hunt by 'tasting' with their suckers
00:44 The unusual receptors that let octopuses hunt by touchResearchers have shown that the suckers of octopuses are covered with specialised receptors that allow them to taste by touching things. Similar receptors are also found in squid, but there are differences that mirror differences in the animals’ hunting behaviours; while octopuses feel for their prey, squid pull things towards themselves before deciding whether or not to eat it.Research article: Kang et al.Research article: Allard et al.Nature video: How octopuses taste with their arms08:48 Research HighlightsHow climate change has been linked to a devastating a...
Source: Nature Podcast - April 12, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Giant black-hole pair from the early Universe gives clues to how galaxies form
00:46 A pair of supermassive black holes in the distant universeSupermassive black holes are found at the centre of galaxies across the universe. But observations of galaxies with more than one – caused by the merging of two galaxies – have been rare. Now, researchers have combined data from a number of telescopes and satellites, to reveal a pair of supermassive blackholes farther from Earth than any pair detected previously. They hope this will offer insights into how galaxies form.Research article: Chen et al.News and Views: Distant supermassive black holes spotted in galaxy merger10:53 Research HighlightsWhy appetit...
Source: Nature Podcast - April 5, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Audio long read: What Turkey ’s earthquake tells us about the science of seismic forecasting
Last month, a magnitude-7.8 earthquake struck Turkey and Syria, killing an estimated 50,000 people. Two decades ago, researchers suggested that an earthquake in this area was likely, but exactly where and when it would strike were unknown.This shows both the promise — and limitations — of the science of earthquake forecasting. Years of research suggest that it may be impossible to predict exactly when an earthquake will occur. As a result, many in the field have now shifted to identifying high risk fault segments to help policymakers take steps to avoid death and destruction.This is an audio version of our Feature...
Source: Nature Podcast - March 31, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

Bacterial ‘syringes’ could inject drugs directly into human cells
00:48 Tiny syringes for drug deliveryA team of researchers have repurposed tiny syringe-like structures produced by some bacteria to deliver molecules directly into human cells. They hope that this method could be used to overcome a big challenge in modern medicine, namely ensuring that therapeutics are delivered into the precise cells that need to be treated.Research article: Kreitz et al.News and Views: Mix-and-match tools for protein injection into cells07:05 Research HighlightsA diamond-like material could protect spacecraft from intense radiation, and how gene editing could help in the treatment of a rare genetic cond...
Source: Nature Podcast - March 29, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

How to make driverless cars safer — expose them to lots of dangerous drivers
00:46 A new test to get autonomous vehicles on the roadTruly autonomous vehicles, ones that don't require a driver to be present and are driven by AI, aren't yet safe for public use. Part of the reason for this is it has been difficult to train them to deal with rare dangerous situations. Now researchers are unveiling a new approach to present lots of these infrequent events to the AI very rapidly, speeding up the training and testing process.Research Article: Feng et al.News and Views: Hazards help autonomous cars to drive safelyVideo: The driving test for driverless cars08:23 Research HighlightsHow bird-flu is adapting t...
Source: Nature Podcast - March 22, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

How to build a virus-proof cell
00:47 An edited genetic code that prevents viral infectionResearchers have engineered bacteria with synthetic genomes to be immune to viral infection. The team streamlined the bacteria’s genetic code, and re-engineered the protein-producing machinery to insert the wrong amino acid if used by a virus, effectively making the bacteria ‘speak’ a different language to any invaders. It’s hoped that this technique could be used to reduce unwanted sharing of genes from modified organisms.Research article: Nyerges et al.News & Views: Synthetic bacterial genome upgraded for viral defence and biocontainment07:42 Research ...
Source: Nature Podcast - March 15, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

How the Australian wildfires devastated the ozone layer
00:47 Wildfire smoke’s chemical composition enhances ozone depletionSmoke from the devastating Australian wildfires of 2019-2020 led to a reduction in ozone levels in the upper atmosphere, but it’s been unclear how. Now, a team proposes that smoke’s particulate matter can enhance the production of ozone depleting chemicals, matching satellite observations during the Australian fires. The results spark concerns that future wildfires, which are set to grow more frequent with ongoing climate change, will undo much of the progress towards restoration of the ozone layer.Research article: Solomon et al.News & Views: Ho...
Source: Nature Podcast - March 8, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

How an increased heart rate could induce anxiety in mice
00:47 How a racing heart could trigger anxietyAnxiety can make the heart beat faster, but could the reverse be true as well? That question has been much debated, but hard to test. Now, a team has shown that artificially increasing a mouse’s heart rate can induce anxiety-like behaviours, and identified an area in the brain that appears to be a key mediator of this response. They hope that this knowledge could help to improve therapies for treating anxiety-related conditions in the future.Research article: Hsueh et al.News & Views: How an anxious heart talks to the brain08:32 Research HighlightsThe chance discovery of ...
Source: Nature Podcast - March 1, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts