Supplementing dietary fibres with a low FODMAP diet in irritable bowel syndrome: a randomized controlled crossover trial
Institution of a low FODMAP diet in patients with irritable bowel syndrome (IBS) may lead to inadequate fiber intake. This trial aimed to investigate the effects of supplementing specific fibers concomitantly with low FODMAP diet on relevant clinical and physiological indices in symptomatic patients with IBS. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 17, 2021 Category: Gastroenterology Authors: Daniel So, Chu K. Yao, Zaid S. Ardalan, Phoebe A. Thwaites, Kourosh Kalantar-Zadeh, Peter R. Gibson, Jane G. Muir Source Type: research

Correction
Walter B, Frank R, Ludwig L, Dikopoulos N, Mayr M, Neu B, Mayer B, Hann A, Meier B, Caca K, Seufferlein T, Meining A. Smartphone Application to Reinforce Education Increases High-Quality Preparation for Colorectal Cancer Screening Colonoscopies in a Randomized Trial. Clin Gastroenterol Hepatol. 2021; 19: 331-338. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Tags: Correction Source Type: research

Exam 1: Comparative Outcomes of Cap Assisted Endoscopic Resection and Endoscopic Submucosal Dissection in Dysplastic Barrett ’s Esophagus
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research

Issue Highlights
Ulcerative colitis (UC) is a chronic inflammatory disease of unknown cause characterized by mucosal inflammation of colon and rectum. Goal of treatment is to reduce mucosal inflammation and to prevent disability, colectomy and colorectal cancer. Aminosalicylates, corticosteroids and thiopurines alone or in combination are established as initial therapies. In recent years various biologicals extended the therapeutic armamentarium in particular for patients refractory or intolerant to conventional therapies or having more severe disease. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Authors: Michael P. Manns Tags: Issue Highlights Source Type: research

Cover
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Source Type: research

Editorial Board
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Source Type: research

Table of Contents
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Source Type: research

Elsewhere in the AGA Journals
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Source Type: research

Information for Authors and Readers
Clinical Gastroenterology and Hepatology is the go-to resource on a broad spectrum of themes in clinical gastroenterology and hepatology. The official clinical practice journal of the AGA Institute brings you the best original research in the field with a unique combination of reviews, editorials, podcasts, video abstracts, and outcomes research —all supporting clinical practice. Articles on education, policy, and practice management highlight issues pertinent to clinicians. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Source Type: research

Prevalence of High and Moderate Risk Nonalcoholic Fatty Liver Disease Among Adults in the United States, 1999 –2016
Nonalcoholic fatty liver disease (NAFLD) subjects with fibrosis stage ≥2 are at high risk for mortality. We aimed to provide national estimates and temporal trends for NAFLD, based on different fibrosis severity. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Authors: Pegah Golabi, James M. Paik, Michael Herring, Elena Younossi, Khaled Kabbara, Zobair M. Younossi Source Type: research

Body Mass Index and PNPLA3 Genetic Variant Modify the Association of Alcohol Consumption With Liver Fat Content
We have read the recent article by De Vincentis et  al1 with interest. The authors concluded that integration of genetics with clinical fibrosis scores refines individual risk and prediction for severe liver diseases, particularly in individuals at risk for nonalcoholic fatty liver disease. Although heavy alcohol consumption is an established risk factor for fatty liver disease,2 the association of low-to-moderate alcohol intake with nonalcoholic fatty liver disease remains controversial. To this end, we assessed the association between alcohol consumption and liver fat content. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Authors: Zhenqiu Liu, Xuehong Zhang, Xingdong Chen Tags: Letter to the Editor Source Type: research

Prevalence of High and Moderate Risk Nonalcoholic Fatty Liver Disease (NAFLD) among Adults in the United States (U.S.), 1999-2016
NAFLD subjects with fibrosis stage ≥2 are at high risk for mortality. We aimed to provide national estimates and temporal trends for NAFLD, based on different fibrosis severity. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Authors: Pegah Golabi, James M. Paik, Michael Herring, Elena Younossi, Khaled Kabbara, Zobair M. Younossi Source Type: research

Body-mass index and PNPLA3 genetic variant modify the association of alcohol consumption with liver fat content
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 16, 2021 Category: Gastroenterology Authors: Zhenqiu Liu, Xuehong Zhang, Xingdong Chen Source Type: research

Emerging Role of Transnasal Endoscopy in Children and Adults
The use of unsedated transnasal endoscopy (TNE) initially was developed by otolaryngologists and was adopted by gastroenterologists in the 1990s for clinically challenging situations in which anatomic or clinical conditions did not allow traditional oral approaches, such as the endoscopic placement of transnasal feeding tubes in critically ill patients, diagnostic evaluation of dysphagia, and upper gastrointestinal bleeding.1 –3 Since then, the use of unsedated TNE in children and adults has grown to include the assessment of a wide variety of conditions in an effort to reduce costs, limit complications, and improve acce...
Source: Clinical Gastroenterology and Hepatology - December 15, 2021 Category: Gastroenterology Authors: Nathalie Nguyen, Jacob Mark, Glenn T. Furuta Tags: Here and Now: Clinical Practice Source Type: research

Food Insecurity is Associated with Mortality Among U.S. Adults with Nonalcoholic Fatty Liver Disease and Advanced Fibrosis
Food insecurity is a growing public health challenge in the U.S. and has been linked to nonalcoholic fatty liver disease (NAFLD) and advanced fibrosis. However, little is known of how food insecurity impacts mortality risk and healthcare utilization (HCU) in chronic liver disease. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - December 15, 2021 Category: Gastroenterology Authors: Ani Kardashian, Jennifer L. Dodge, Norah A. Terrault Source Type: research