Maintenance therapy with the lowest effective dose of oral viscous budesonide in children with Eosinophilic Esophagitis
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 19, 2021 Category: Gastroenterology Authors: Salvatore Oliva, Danila Volpe, Giusy Russo, Silvio Veraldi, Paola Papoff, Carla Giordano, Cosimo Ruggiero, Chiara Maria Trovato, Gianluca Terrin, Danilo Rossetti Source Type: research

Beyond Metoclopramide for Gastroparesis
Gastroparesis is characterized by diverse upper gastrointestinal symptoms including nausea, vomiting, early satiety, postprandial fullness, bloating, and upper abdominal pain; slow gastric emptying of solids; and absence of gastric outlet or intestinal obstruction. In clinical practice, diabetes mellitus, and idiopathic and iatrogenic (postsurgical or medication) gastroparesis are the most frequently encountered forms. In addition, diseases affecting the neural control of the upper gut (such as Parkinson ’s disease, or effects of dopaminergic agents), and diseases that damage intrinsic nerves or smooth muscle also cause ...
Source: Clinical Gastroenterology and Hepatology - September 18, 2021 Category: Gastroenterology Authors: Michael Camilleri Tags: Here and Now: Clinical Practice Source Type: research

Low prevalence of screen-detected colorectal cancer in an average-risk population: the new normal
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 18, 2021 Category: Gastroenterology Authors: Aasma Shaukat, Tracey L. Marsh, Seth D. Crockett, Sapna Syngal, Robert S. Bresalier, Dean E. Brenner, EDRN Consortium Source Type: research

The Modified Pancreatitis Activity Scoring System Shows Distinct Trajectories in Acute Pancreatitis: An International Study
The aims of this study were to: 1) assess the performance of the pancreatitis activity scoring system (PASS) in a large intercontinental AP cohort, 2) investigate whether a modified PASS, yields a similar predictive accuracy and produces distinct early trajectories between severity subgroups. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 17, 2021 Category: Gastroenterology Authors: Pedram Paragomi, Alice Hinton, Ioannis Pothoulakis, Rupjyoti Talukdar, Rakesh Kochhar, Mahesh K. Goenka, Aiste Gulla, Jose A. Gonzalez, Vikesh K. Singh, Miguel Ferreira Bigado, Tyler Stevens, Sorin T. Barbu, Haq Nawaz, Silvia C. Gutierrez, Narcis Zarnescu Source Type: research

Reply
We would like to thank Soullane et  al1 for their letter commenting on our paper “Maternal and perinatal risk factors for pediatric non-alcoholic fatty liver disease: A systematic review.”2 We have carefully read their letter and would like to address their remarks. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 15, 2021 Category: Gastroenterology Authors: Ilya Querter, Ruth de Bruyne, Anja Geerts, Sander Lefere Tags: Letter to the Editor Source Type: research

Reply
We thank the authors Duan et  al1 for the interest in our study and their comments. The concerns raised primarily arise from the generalizability of results and the risk of bias from unmeasured confounders. We fully agree that our results should be interpreted with respect to the study population. As we have noted in our artic le, the heterogenous study populations from the studies included in the meta-analysis may partly explain their conflicting results. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 15, 2021 Category: Gastroenterology Authors: Simone Bastrup Israelsen, Jesper Hallas, Thomas Benfield Tags: Letter to the Editor Source Type: research

A Dropped Gallstone Leading to Abdominal Pain and Bloody Diarrhea
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 15, 2021 Category: Gastroenterology Authors: Brian M. Fung, Aravind Sugumar, Jen-Jung Pan Tags: Image of the Month Source Type: research

Letter to the Editor Reply in response to “COVID-19 mortality – The culprit may not be proton pump inhibitors” (CGH-D-21-01887)
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 15, 2021 Category: Gastroenterology Authors: Simone Bastrup Israelsen, Jesper Hallas, Thomas Benfield Source Type: research

Reply to ‘Perinatal risk factors for pediatric non-alcoholic fatty liver disease: Impact of inborn errors of metabolism’
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 15, 2021 Category: Gastroenterology Authors: Ilya Querter, Ruth De Bruyne, Anja Geerts, Sander Lefere Source Type: research

Reply
In a recent publication on colonoscopy-related mortality in a fecal immunochemical test (FIT)-based colorectal cancer screening program we estimated the occurrence of fatal adverse events caused by colonoscopy as follow-up of a positive FIT result.1 In response to our findings, Weiss and colleagues stated that the complications by follow-up colonoscopy after positive FIT should not be attributed to FIT screening, because other less invasive follow-up alternatives are available. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 14, 2021 Category: Gastroenterology Authors: Arthur I. Kooyker, Iris Lansdorp-Vogelaar, Monique E. Van Leerdam Tags: Letter to the Editor Source Type: research

Colonoscopy and Its Complications are Inseparable of FIT-Based Screening
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 14, 2021 Category: Gastroenterology Authors: A.I. Kooyker, I. Lansdorp-Vogelaar, M.E. van Leerdam Source Type: research

Deep Learning Computer-aided Polyp Detection Reduces Adenoma Miss Rate: A United States Multi-center Randomized Tandem Colonoscopy Study (CADeT-CS Trial)
Artificial intelligence-based computer-aided polyp detection (CADe) systems are intended to address the issue of missed polyps during colonoscopy. The effect of CADe during screening and surveillance colonoscopy has not previously been studied in a United States (U.S.) population. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 13, 2021 Category: Gastroenterology Authors: Jeremy R. Glissen Brown, Nabil M. Mansour, Pu Wang, Maria Aguilera Chuchuca, Scott B. Minchenberg, Madhuri Chandnani, Lin Liu, Seth A. Gross, Neil Sengupta, Tyler M. Berzin Source Type: research

DEEP LEARNING COMPUTER-AIDED POLYP DETECTION REDUCES ADENOMA MISS RATE: A U.S. MULTI-CENTER RANDOMIZED TANDEM COLONOSCOPY STUDY (CADeT-CS Trial)
Artificial intelligence-based computer aided polyp detection (CADe) systems are intended to address the issue of missed polyps during colonoscopy. The effect of CADe during screening and surveillance colonoscopy has not previously been studied in a United States population. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 13, 2021 Category: Gastroenterology Authors: Jeremy R. Glissen Brown, Nabil M. Mansour, Pu Wang, Maria Aguilera Chuchuca, Scott B. Minchenberg, Madhuri Chandnani, Lin Liu, Seth A. Gross, Neil Sengupta, Tyler M. Berzin Source Type: research

Untangling the Influence of Sex Hormones on Nonalcoholic Fatty Liver Disease in Women
We read with interest the recent publication by Wang et  al1 on the influence of sex hormones and reproductive factors on NAFLD prevalence in women. The intersection of reproductive health and liver disease, including hormonal influence on NAFLD, has gained recognition as the marked rise of NAFLD in young adults and the implications of NAFLD on women’ s reproductive health is acknowledged.2 Although the current study has added to the expanding literature, we do note some aspects of defining risk factors and interpreting estrogen exposure that may benefit from further endocrine-based characterization. (Source: Clinical G...
Source: Clinical Gastroenterology and Hepatology - September 9, 2021 Category: Gastroenterology Authors: Monika Sarkar, Marcelle Cedars Tags: Letter to the Editor Source Type: research

Intestinal Spirochetosis
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 9, 2021 Category: Gastroenterology Authors: Naoki Matsuura Tags: Image of the Month Source Type: research