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A Meta-Analysis on the Global Prevalence, Risk factors and Screening of Coronary Heart Disease in Non-alcoholic Fatty Liver Disease
Cardiovascular disease remains the leading cause of death in patients with non-alcoholic fatty liver disease (NAFLD). Studies examining the association of coronary heart disease (CHD) and NAFLD are cofounded by various cardiometabolic factors particularly diabetes and body mass index. Hence, we seek to explore such association by investigating the global prevalence, independent risk factors and influence of steatosis grade on manifestation of CHD among patients with NAFLD. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 21, 2021 Category: Gastroenterology Authors: Jonathan Zhi Kai Toh, Xin-Hui Pan, Phoebe Wen Lin Tay, Cheng Han Ng, Jie Ning Yong, Jieling Xiao, Jin Hean Koh, En Ying Tan, Eunice Xiang Xuan Tan, Yock Young Dan, Poay Huan Loh, Roger Foo, Nicholas WS. Chew, Arun J. Sanyal, Mark D. Muthiah, Mohammad Shad Source Type: research

Safety and Efficacy of Glucagon-like Peptide 1 Receptor Agonists in patients with cirrhosis
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 21, 2021 Category: Gastroenterology Authors: S. Morris, M.J. Armstrong, P.N. Newsome Source Type: research

Comment on Study of Risk of pancreatitis following biliary stenting with/without endoscopic sphincterotomy
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 21, 2021 Category: Gastroenterology Authors: Jia-su Li, Jun Fang, Feng Liu Source Type: research

Issue Highlights
The risk of inflammatory bowel disease (IBD) within families continues to be elucidated, and data are lacking on this topic in Asian countries. In this issue of Clinical Gastroenterology and Hepatology, Kim and colleagues1 conducted a retrospective cohort study within the South Korea National Health Insurance Database, from 2002-2017. This data source is derived from the universal health system in South Korea, is population-based, and specifically includes family history information. From a cohort of nearly 22 million individuals, the investigators identified 45,717 with ulcerative colitis and 17,848 with Crohn ’s diseas...
Source: Clinical Gastroenterology and Hepatology - September 20, 2021 Category: Gastroenterology Authors: Evan S. Dellon Tags: Issue Highlights Source Type: research

Cover
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 20, 2021 Category: Gastroenterology Source Type: research

Editorial Board
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 20, 2021 Category: Gastroenterology Source Type: research

Table of Contents
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 20, 2021 Category: Gastroenterology Source Type: research

Elsewhere in the AGA Journals
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 20, 2021 Category: Gastroenterology Source Type: research

Information for Authors and Readers
Clinical Gastroenterology and Hepatology is the go-to resource on a broad spectrum of themes in clinical gastroenterology and hepatology. The official clinical practice journal of the AGA Institute brings you the best original research in the field with a unique combination of reviews, editorials, podcasts, video abstracts, and outcomes research —all supporting clinical practice. Articles on education, policy, and practice management highlight issues pertinent to clinicians. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 20, 2021 Category: Gastroenterology Source Type: research

When food moves from friend to foe: Why avoidant/restrictive food intake matters in irritable bowel syndrome
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 20, 2021 Category: Gastroenterology Authors: Helen Burton Murray, Kyle Staller Source Type: research

Cachexia is Prevalent in Patients with Hepatocellular Carcinoma and Associated with Worse Prognosis
Cancer cachexia is a wasting syndrome associated with functional impairment and reduced survival that impacts up to 50% of patients with gastrointestinal cancers. However, data are limited on the prevalence and clinical significance of cachexia in patients with hepatocellular carcinoma (HCC). (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 20, 2021 Category: Gastroenterology Authors: Nicole E. Rich, Samuel Phen, Nirali Desai, Sukul Mittal, Adam C. Yopp, Ju Dong Yang, Jorge A. Marrero, Puneeth Iyengar, Rodney E. Infante, Amit G. Singal Source Type: research

Reply
We appreciate the comments by Akiyama et  al1 regarding our recent publication evaluating the “Incidence, Risk Factors, and Outcomes of Pouchitis and Pouch-Related Complications in Patients with Ulcerative Colitis.”2 Given the authors’ recent findings of a high risk of developing pouch inflammation over long-term follow-up,3 and pri or long-term studies indicating the risk of pouchitis may be as high as 80%,4 we believe that these studies should continue to prompt future investigations into the underlying drivers of pouchitis and other inflammatory conditions of the pouch. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 19, 2021 Category: Gastroenterology Authors: Edward L. Barnes Tags: Letter to the Editor Source Type: research

Reply
We thank Dr. Jena and colleagues for their interest in our study1 and for their insightful comments. As they have indicated, we know from considerable data2 that difficult cannulation is associated with postendoscopic retrograde cholangiopancreatography pancreatitis (PEP), and that inadvertent pancreatic duct cannulation/guidewire insertion and long cannulation time (ie, difficult cannulation) are key risk factors for PEP.3 Although we did not acquire detailed information regarding how many times and for how long the fellow/trainee attempted cannulation, data for the overall cannulation times and unintended pancreatic duct...
Source: Clinical Gastroenterology and Hepatology - September 19, 2021 Category: Gastroenterology Authors: Shin Kato, Masaki Kuwatani Tags: Letter to the Editor Source Type: research

Standardized Approaches to Outcomes after Ileal Pouch-Anal Anastomosis
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 19, 2021 Category: Gastroenterology Authors: Edward L. Barnes Source Type: research

Response to “Endoscopic Sphincterotomy and Post ERCP pancreatitis: In an era of declining mystery, the unknown persists”
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - September 19, 2021 Category: Gastroenterology Authors: Shin Kato, Masaki Kuwatani Source Type: research