Performance of noninvasive tests of fibrosis among Asians, Hispanic and non-Hispanic Whites in the STELLAR trials
This study evaluated the performance of noninvasive tests among White and Asian patients in the STELLAR trials (NCT03053050 and NCT03053063), which evaluated selonsertib in patients with advanced (F3-F4) fibrosis due to nonalcoholic steatohepatitis (NASH). (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 21, 2022 Category: Gastroenterology Authors: Vincent Wai-Sun Wong, Won Young Tak, George Boon Bee Goh, Pin-Nan Cheng, Eric J. Lawitz, Zobair M. Younossi, Raj Vuppalanchi, Ziad Younes, Naim Alkhouri, Lulu Wang, Jialuo Liu, Kathryn Kersey, Robert P. Myers, Stephen A. Harrison, Zachary Goodman, Michael Source Type: research

Humoral response to 2-dose BNT162b2 mRNA COVID-19 vaccination in liver transplant recipients.
In the context of the Italian SARS-CoV-2 vaccination program, liver transplant (LT) recipients were prioritized for vaccine administration, although the lower response to vaccines is a well known problem in this population. We aimed to evaluate immunogenicity of BNT162b2 mRNA vaccine in LT recipients and healthy controls and to identify factors associated with negative response to vaccine. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 19, 2022 Category: Gastroenterology Authors: Maria Guarino, Ilaria Esposito, Giuseppe Portella, Valentina Cossiga, Ilaria Loperto, Raffaella Tortora, Michele Cennamo, Mario Capasso, Daniela Terracciano, Alfonso Galeota Lanza, Sarah Di Somma, Francesco Paolo Picciotto, Filomena Morisco, UniNa Collabo Source Type: research

Risk of infections with ustekinumab and tofacitinib compared to tumor necrosis factor α antagonists in inflammatory bowel diseases
The comparative safety of therapies is important to inform relative positioning within the therapeutic algorithm. Tumor necrosis factor α antagonists (anti-TNF) are associated with an increased risk of infections. Whether there is a similar increase with ustekinumab (UST) or tofacitinib has not been established. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 19, 2022 Category: Gastroenterology Authors: David Cheng, Bharati Kochar, Tianxi Cai, Ashwin N. Ananthakrishnan Source Type: research

Exam 2: Risk of Serious Infections With Vedolizumab Versus Tumor Necrosis Factor Antagonists in Patients With Inflammatory Bowel Disease
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 18, 2022 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research

A low FODMAP diet reduces symptoms in treated celiac patients with ongoing symptoms – a randomized controlled trial
Gluten-free diet usually leads to mucosal remission in celiac disease, but persistent symptoms are common. Low FODMAP diet is an established treatment for irritable bowel syndrome (IBS). We have assessed the efficacy of a moderately low FODMAP diet on persistent symptoms in treated celiac patients. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 17, 2022 Category: Gastroenterology Authors: Frida van Megen, Gry I. Skodje, Simon Lergenmuller, Stephanie Z ühlke, Lars Aabakken, Marit B. Veierød, Christine Henriksen, Knut E.A. Lundin Source Type: research

Clinical Outcomes in Biopsy-Proven Nonalcoholic Fatty Liver Disease Patients: A Multicenter Registry-Based Cohort Study
There are no detailed reports of clinical outcomes in Asian patients with nonalcoholic fatty liver disease (NAFLD) who undergo liver biopsy. We aimed to investigate the clinical outcomes of a large cohort of Asian patients with biopsy-proven NAFLD and evaluate the specific effects of nonalcoholic steatohepatitis (NASH) and fibrosis stage. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 17, 2022 Category: Gastroenterology Authors: Hideki Fujii, Michihiro Iwaki, Hideki Hayashi, Hidenori Toyoda, Satoshi Oeda, Hideyuki Hyogo, Miwa Kawanaka, Asahiro Morishita, Kensuke Munekage, Kazuhito Kawata, Sakura Yamamura, Koji Sawada, Tatsuji Maeshiro, Hiroshi Tobita, Yuichi Yoshida, Masafumi Nai Source Type: research

Exam 1: Risk of Serious Infections With Vedolizumab Versus Tumor Necrosis Factor Antagonists in Patients With Inflammatory Bowel Disease
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 16, 2022 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research

Issue Highlights
Although colonoscopy with polypectomy has been shown to reduce the overall incidence and mortality from colorectal cancer (CRC), the impact on proximal colon cancers has been harder to demonstrate. Retroflexion in the right colon (RC) and re-examining the RC with a second forward view (SFV) have been shown to increase RC ADR but studies have been limited to a single site, raising the question of generalizability. Tang et  al.1 conducted an international multicenter randomized trial evaluating SFV vs standard withdrawal colonoscopy (SWC) on RC ADR. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 16, 2022 Category: Gastroenterology Authors: Jane Onken Tags: Issue Highlights Source Type: research

Exam 1: Magnitude and Time-Trend Analysis of Postendoscopy Esophageal Adenocarcinoma: A Systematic Review and Meta-analysis
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 16, 2022 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activities Source Type: research

Cover
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 16, 2022 Category: Gastroenterology Source Type: research

Editorial Board
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 16, 2022 Category: Gastroenterology Source Type: research

Table of Contents
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 16, 2022 Category: Gastroenterology Source Type: research

Elsewhere in the AGA Journals
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 16, 2022 Category: Gastroenterology Source Type: research

Information for Authors and Readers
Clinical Gastroenterology and Hepatology is the go-to resource on a broad spectrum of themes in clinical gastroenterology and hepatology. The official clinical practice journal of the AGA Institute brings you the best original research in the field with a unique combination of reviews, editorials, podcasts, video abstracts, and outcomes research —all supporting clinical practice. Articles on education, policy, and practice management highlight issues pertinent to clinicians. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 16, 2022 Category: Gastroenterology Source Type: research

MAFLD and pregnancy – What are the consequences?
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - January 16, 2022 Category: Gastroenterology Authors: Akiko Nakanishi, Linda Henry, Mindie H. Nguyen Source Type: research