Metastases to the pituitary gland: insights from the German pituitary tumor registry
AbstractMetastatic involvement of the pituitary gland is a rare but clinically significant phenomenon, that often poses diagnostic and therapeutic challenges. The aim of this study was to provide a comprehensive analysis of the origin of pituitary metastases using data from the German Pituitary Tumor Registry, one of the globally largest collections of pituitary pathology specimens. Here, we report data from a retrospective analysis of patients with metastases to the pituitary registered between 1990 and 2022. Out of 17,896 pituitary cases in the registry during this period, a total of 96 metastases to the pituitary gland ...
Source: Pituitary - October 30, 2023 Category: Endocrinology Source Type: research

Letter to the editor – pituitary tumors and diaphragma sellae
. (Source: British Journal of Neurosurgery)
Source: British Journal of Neurosurgery - October 27, 2023 Category: Neurosurgery Authors: Atul Goela Department of Neurosurgery, Lilavati Hospital and Research Center, Bandra, Mumbai, Indiab Department of Neurosurgery, R.N Cooper Hospital and Medical College, Mumbai, Indiac Department of Neurosurgery, Bombay Hospital Institute of Medical Scien Source Type: research

Correlation between tumor invasion and somatostatin receptor subtypes in acromegaly
CONCLUSIONS: Tumor invasion is negatively correlated with SSTR2 level but is not associated with other SSTR subtypes. Patients with invasive tumors have a poorer response to SSA therapy, which may be due to the low level of SSTR2 expression. Therefore, SSTR2 could be considered as a routine investigative marker for aiding management of postoperative residual tumors.PMID:37856412 | DOI:10.3171/2023.7.JNS23858 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 19, 2023 Category: Neurosurgery Authors: Shaolin Zhang Shun Yao Jinping Chen Farhana Akter Jia Yang Dimin Zhu Ailiang Zeng Wenli Chen Zhigang Mao Yonghong Zhu Haijun Wang Source Type: research

Correlation between tumor invasion and somatostatin receptor subtypes in acromegaly
CONCLUSIONS: Tumor invasion is negatively correlated with SSTR2 level but is not associated with other SSTR subtypes. Patients with invasive tumors have a poorer response to SSA therapy, which may be due to the low level of SSTR2 expression. Therefore, SSTR2 could be considered as a routine investigative marker for aiding management of postoperative residual tumors.PMID:37856412 | DOI:10.3171/2023.7.JNS23858 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - October 19, 2023 Category: Neurosurgery Authors: Shaolin Zhang Shun Yao Jinping Chen Farhana Akter Jia Yang Dimin Zhu Ailiang Zeng Wenli Chen Zhigang Mao Yonghong Zhu Haijun Wang Source Type: research

Pronounced hyperostosis frontalis interna and co ‐occurring lesions in the skull base suggestive of a pituitary tumor in a woman from medieval Germany
AbstractHyperostosis frontalis interna (HFI) is an osseous overgrowth characterized by symmetrical, irregular bone apposition on the internal table of the frontal bone, which preferentially occurs in females. In 1719, Morgagni described the condition as one sign of a triad comprising HFI, hirsutism, and obesity (Morgagni's syndrome). The etiopathogenesis of HFI is largely unresolved, but the condition is frequently associated with metabolic, endocrine, and neuropsychiatric disorders. In archaeological cases, which rely solely on dry bone diagnosis, the cause of HFI generally remains unknown, as is also the case regarding a...
Source: International Journal of Osteoarchaeology - October 19, 2023 Category: Science Authors: Stefan Flohr, Carsten Witzel, Uwe Kierdorf Tags: SHORT REPORT Source Type: research

Pituitary adenoma presenting as isolated oculomotor nerve palsy
CONCLUSION: These cases illustrate the need to consider isolated oculomotor nerve palsy as an initial manifestation of a relatively small pituitary adenoma with neither apoplexy nor CS invasion. Based on the characteristic radiological findings, early surgical treatment is recommended to preserve oculomotor function.PMID:37810282 | PMC:PMC10559479 | DOI:10.25259/SNI_421_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - October 9, 2023 Category: Neurosurgery Authors: Jun Masuoka Fumitaka Yoshioka Kohei Inoue Takashi Furukawa Hiroshi Ito Atsushi Ogata Yukiko Nakahara Tatsuya Abe Source Type: research