The correlation among Claudin-9, Tyrosine kinase-2, and Signal transducers and activators of transcription-3 expressions in non-functioning pituitary adenoma and invasiveness
CONCLUSION: Upregulated CLDN9 may increase the NFPA invasiveness through STAT3. In addition, low TYK2 expression might enhance the invasiveness in NFPA, which needs further studies to confirm. These results could provide a promising research leads for targeted treatment of NFPA.PMID:38131177 (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - December 22, 2023 Category: Endocrinology Authors: Abudukadier Yasen Maimaitiyiming Tuoheti Ba Tu Cheng Zhang Yu Ding Fey Tang Yonggang Wu Source Type: research
Aerobic exercise interventions to address impaired quality of life in patients with pituitary tumors
by Christopher S. Hong, Timothy R. Smith
Patients with pituitary tumors may experience persistent fatigue and reduced physical activity, based on subjective measures after treatment. These symptoms may persist despite gross total resection of their tumors and biochemical normalization of pituitary function. While reduced quality of life has been commonly acknowledged in pituitary tumor patients, there is a lack of studies on what interventions may be best implemented to ameliorate these issues, particularly when hormonal levels have otherwise normalized. Aerobic exercise programs have been previously described to ameliora...
Source: PLoS One - December 15, 2023 Category: Biomedical Science Authors: Christopher S. Hong Source Type: research
Stereotactic radiosurgery for non-functioning pituitary tumor: a multicenter study of new pituitary hormone deficiency
CONCLUSION: SRS provides long-term tumor control with a 15.3% risk of hypopituitarism at 10 years.PMID:38095431 | DOI:10.1093/neuonc/noad215 (Source: Cancer Control)
Source: Cancer Control - December 14, 2023 Category: Cancer & Oncology Authors: Chloe Dumot Georgios Mantziaris Sam Dayawansa Selcuk Peker Yavuz Samanci Ahmed M Nabeel Wael A Reda Sameh R Tawadros Khaled AbdelKarim Amr M N El-Shehaby Reem M Emad Ahmed Ragab Abdelsalam Roman Liscak Jaromir May Elad Mashiach Fernando De Nigris Vasconce Source Type: research
Clinical and Molecular Characteristics of Gonadotroph Pituitary Tumors According to the WHO Classification
This study indicates that hormone-negative GnPT tend to occur in older patients but do not significantly differ from other GnPT in terms of invasion or proliferation. It also points out the current limits of D2R immunostaining in such tumors. (Source: Endocrine Pathology)
Source: Endocrine Pathology - December 14, 2023 Category: Pathology Source Type: research
FAF1 Gene Involvement in Pituitary Corticotroph Tumors
In conclusion, we identified two FAF1 variants in patients diagnosed with CD with a potential pathogenic effect on the protein function and structure. Our in vitro and in vivo studies did not reveal an association of FAF1 defects with pituitary tumorigenesis and further studies may be needed to understand any association.PMID:38065537 | DOI:10.1055/a-2192-1761 (Source: Cell Research)
Source: Cell Research - December 8, 2023 Category: Cytology Authors: Matthew Nguyen Andrea Gutierrez Maria Fabio R Faucz Giampaolo Trivellin Constantine A Stratakis Christina Tatsi Source Type: research
FAF1 Gene Involvement in Pituitary Corticotroph
Tumors
In conclusion, we identified two
FAF1 variants in patients diagnosed with CD with a potential
pathogenic effect on the protein function and structure. Our in vitro and in
vivo studies did not reveal an association of FAF1 defects with pituitary
tumorigenesis and further studies may be needed to understand any
association. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Hormone and Metabolic Research)
Source: Hormone and Metabolic Research - December 8, 2023 Category: Endocrinology Authors: Nguyen, Matthew Maria, Andrea Gutierrez Faucz, Fabio R. Trivellin, Giampaolo Stratakis, Constantine A. Tatsi, Christina Tags: Original Article: Endocrine Research Source Type: research
Internal carotid artery injury during endoscopic transsphenoidal pituitary surgery: risk factors, management
CONCLUSIONS: We proposed a treatment plan for ICA injuries encountered during endoscopic transsphenoidal surgery and described our hemostasis process, methods of endovascular treatment, and means of postoperative follow-up in detail.PMID:38052154 | DOI:10.1016/j.neuchi.2023.101515 (Source: Neuro-Chirurgie)
Source: Neuro-Chirurgie - December 5, 2023 Category: Neurosurgery Authors: Xin Ma Yu Zhang Zhi-Jun Yang Wang Bo Xin-Chao Wang Chao Zhang Pi-Nan Liu Zhi-Yong Bi Source Type: research
Internal carotid artery injury during endoscopic transsphenoidal pituitary surgery: risk factors, management
CONCLUSIONS: We proposed a treatment plan for ICA injuries encountered during endoscopic transsphenoidal surgery and described our hemostasis process, methods of endovascular treatment, and means of postoperative follow-up in detail.PMID:38052154 | DOI:10.1016/j.neuchi.2023.101515 (Source: Neurochirurgie)
Source: Neurochirurgie - December 5, 2023 Category: Neurosurgery Authors: Xin Ma Yu Zhang Zhi-Jun Yang Wang Bo Xin-Chao Wang Chao Zhang Pi-Nan Liu Zhi-Yong Bi Source Type: research
Temozolomide for aggressive pituitary tumors:-A literature review
Asian J Surg. 2023 Nov 29:S1015-9584(23)01884-5. doi: 10.1016/j.asjsur.2023.11.106. Online ahead of print.NO ABSTRACTPMID:38030489 | DOI:10.1016/j.asjsur.2023.11.106 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - November 29, 2023 Category: Surgery Authors: Hu Hui-Zheng Lei Lei Source Type: research
Temozolomide for aggressive pituitary tumors:-A literature review
Asian J Surg. 2023 Nov 29:S1015-9584(23)01884-5. doi: 10.1016/j.asjsur.2023.11.106. Online ahead of print.NO ABSTRACTPMID:38030489 | DOI:10.1016/j.asjsur.2023.11.106 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - November 29, 2023 Category: Surgery Authors: Hu Hui-Zheng Lei Lei Source Type: research
Cancers, Vol. 15, Pages 5526: Pituitary Tumors: Molecular Insights, Diagnosis, and Targeted Therapy
ama
The anterior pituitary gland comprises a heterogeneous population of pituitary cells [...] (Source: Cancers)
Source: Cancers - November 22, 2023 Category: Cancer & Oncology Authors: Kazunori Kageyama Mitsuru Nishiyama Tags: Editorial Source Type: research
