Benign Glioma
Adv Exp Med Biol. 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2.ABSTRACTBenign glioma broadly refers to a heterogeneous group of slow-growing glial tumors with low proliferative rates and a more indolent clinical course. These tumors may also be described as "low-grade" glioma (LGG) and are classified as WHO grade I or II lesions according to the Classification of Tumors of the Central Nervous System (CNS) (Louis et al. in Acta Neuropathol 114:97-109, 2007). Advances in molecular genetics have improved understanding of glioma tumorigenesis, leading to the identification of common mutation profiles with significant trea...
Source: Advances in Experimental Medicine and Biology - July 15, 2023 Category: Research Authors: Peter B Wu Anna C Filley Michael L Miller Jeffrey N Bruce Source Type: research
A molecular study of pediatric pilomyxoid and pilocytic astrocytomas: Genome-wide copy number screening, retrospective analysis of clinicopathological features and long-term clinical outcome
ConclusionOur study is the first report of a large cohort of patients with PMA and PA in the Saudi population that provides detailed clinical features, genomic copy number changes, and outcome of these pediatric tumors and may help better diagnosis and characterization of PMA. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - February 13, 2023 Category: Cancer & Oncology Source Type: research
Spectrum of qualitative and quantitative imaging of pilomyxoid, intermediate pilomyxoid and pilocytic astrocytomas in relation to their genetic alterations
ConclusionPMA and IPT do not demonstrate aggressive imaging characteristics in respect to their diffusion imaging with ADC values being higher than PA. Lack ofBRAF-alteration in PMA corresponded to atypical location of tumors with atypical driver mutations and mechanisms. (Source: Neuroradiology)
Source: Neuroradiology - January 1, 2023 Category: Radiology Source Type: research
Pediatric pilomyxoid astrocytoma - ophthalmic and neuroradiologic manifestations
Eur J Ophthalmol. 2021 Nov 29:11206721211055620. doi: 10.1177/11206721211055620. Online ahead of print.NO ABSTRACTPMID:34841927 | DOI:10.1177/11206721211055620 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - November 29, 2021 Category: Opthalmology Authors: Joyce N Mbekeani Maaly Abdel Fattah Anwar Ul Haq Essam Al Shail Manzoor Ahmed Source Type: research
Pediatric pilomyxoid astrocytoma - ophthalmic and neuroradiologic manifestations
Eur J Ophthalmol. 2021 Nov 29:11206721211055620. doi: 10.1177/11206721211055620. Online ahead of print.NO ABSTRACTPMID:34841927 | DOI:10.1177/11206721211055620 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - November 29, 2021 Category: Opthalmology Authors: Joyce N Mbekeani Maaly Abdel Fattah Anwar Ul Haq Essam Al Shail Manzoor Ahmed Source Type: research
Hypothalamic Pilomyxoid Astrocytoma in a Child with Lipodystrophy [PEDIATRICS]
SUMMARY:
Pilomyxoid astrocytoma is a rare form of pediatric CNS malignancy first classified in 2007 by the World Health Organization. The tumors are similar to pilocytic astrocytomas, sharing both some imaging and histologic traits. However, pilomyxoid astrocytomas portend a more ominous prognosis, with more aggressive local tendencies and a greater proclivity for leptomeningeal spread. Although tissue sampling is ultimately required to differentiate pilocytic astrocytomas and pilomyxoid astrocytomas, some imaging features can be used to suggest a pilomyxoid astrocytoma, including homogeneous enhancement, leptomeningeal se...
Source: American Journal of Neuroradiology - August 11, 2021 Category: Radiology Authors: Benson, J. C., Trejo-Lopez, J., Bach, S. E., Schwartz, J., Kaufmann, T. J., Eckel, L., Guerin, J. Tags: PEDIATRICS Source Type: research
Pilomyxoid astrocytoma of the thoracic spinal cord: Extremely rare case report of over 70 ‐year‐old patient
The Pilomyxoid is rare tumor in elderly population, in addition to the occurrence of an isolated lesion in spinal cord is extremely rare in non-pediatric population. Taking biopsy and subtotal resection is the starting point in essential approach for the treatment. After defining the histopathological nature of the tumor and specified that is Pilomyxoid, the next step is the combination of reoperation and adjuvant therapy. AbstractThe Pilomyxoid is rare tumor in elderly population, in addition to the occurrence of an isolated lesion in spinal cord is extremely rare in non-pediatric population. Taking biopsy and subtotal re...
Source: Clinical Case Reports - July 21, 2021 Category: General Medicine Authors: Mohamed A. Almzeogi,
Zeyad A. Abousabie,
Jelena Kostic,
Aleksandar M. Janicijevic,
Goran Tasic Tags: CASE REPORT Source Type: research
A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features
Indian J Pathol Microbiol. 2021 Apr-Jun;64(2):354-357. doi: 10.4103/IJPM.IJPM_209_20.ABSTRACTPilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis. PMA is generally seen in young children and tend to occur in the hypothalamic-chiasmatic region. Their presence in other parts of the brain in the non pediatric age group is uncommon. To the best of our knowledge we are presenting first case of cerebellar PMA associated with neurofibromatosis...
Source: Indian Journal of Pathology and Microbiology - April 14, 2021 Category: Pathology Authors: Siddhi Gaurish Sinai Khandeparkar Shital Subhash Gosavi Bageshri P Gogate Nikhil Talathi Source Type: research
A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features
Indian J Pathol Microbiol. 2021 Apr-Jun;64(2):354-357. doi: 10.4103/IJPM.IJPM_209_20.ABSTRACTPilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis. PMA is generally seen in young children and tend to occur in the hypothalamic-chiasmatic region. Their presence in other parts of the brain in the non pediatric age group is uncommon. To the best of our knowledge we are presenting first case of cerebellar PMA associated with neurofibromatosis...
Source: Indian Journal of Pathology and Microbiology - April 14, 2021 Category: Pathology Authors: Siddhi Gaurish Sinai Khandeparkar Shital Subhash Gosavi Bageshri P Gogate Nikhil Talathi Source Type: research
A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features
Indian J Pathol Microbiol. 2021 Apr-Jun;64(2):354-357. doi: 10.4103/IJPM.IJPM_209_20.ABSTRACTPilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis. PMA is generally seen in young children and tend to occur in the hypothalamic-chiasmatic region. Their presence in other parts of the brain in the non pediatric age group is uncommon. To the best of our knowledge we are presenting first case of cerebellar PMA associated with neurofibromatosis...
Source: Indian Journal of Pathology and Microbiology - April 14, 2021 Category: Pathology Authors: Siddhi Gaurish Sinai Khandeparkar Shital Subhash Gosavi Bageshri P Gogate Nikhil Talathi Source Type: research
A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features
Indian J Pathol Microbiol. 2021 Apr-Jun;64(2):354-357. doi: 10.4103/IJPM.IJPM_209_20.ABSTRACTPilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis. PMA is generally seen in young children and tend to occur in the hypothalamic-chiasmatic region. Their presence in other parts of the brain in the non pediatric age group is uncommon. To the best of our knowledge we are presenting first case of cerebellar PMA associated with neurofibromatosis...
Source: Indian Journal of Pathology and Microbiology - April 14, 2021 Category: Pathology Authors: Siddhi Gaurish Sinai Khandeparkar Shital Subhash Gosavi Bageshri P Gogate Nikhil Talathi Source Type: research
A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features
Indian J Pathol Microbiol. 2021 Apr-Jun;64(2):354-357. doi: 10.4103/IJPM.IJPM_209_20.ABSTRACTPilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis. PMA is generally seen in young children and tend to occur in the hypothalamic-chiasmatic region. Their presence in other parts of the brain in the non pediatric age group is uncommon. To the best of our knowledge we are presenting first case of cerebellar PMA associated with neurofibromatosis...
Source: Indian Journal of Pathology and Microbiology - April 14, 2021 Category: Pathology Authors: Siddhi Gaurish Sinai Khandeparkar Shital Subhash Gosavi Bageshri P Gogate Nikhil Talathi Source Type: research
A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features
Indian J Pathol Microbiol. 2021 Apr-Jun;64(2):354-357. doi: 10.4103/IJPM.IJPM_209_20.ABSTRACTPilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis. PMA is generally seen in young children and tend to occur in the hypothalamic-chiasmatic region. Their presence in other parts of the brain in the non pediatric age group is uncommon. To the best of our knowledge we are presenting first case of cerebellar PMA associated with neurofibromatosis...
Source: Indian Journal of Pathology and Microbiology - April 14, 2021 Category: Pathology Authors: Siddhi Gaurish Sinai Khandeparkar Shital Subhash Gosavi Bageshri P Gogate Nikhil Talathi Source Type: research
