Incidence of Laboratory Tumor Lysis Syndrome in CAR T-Cell Recipients
Tumor lysis syndrome (TLS) is a complication commonly seen in hematological malignancies after patients receive antineoplastics due to the rapid release of cell contents including potassium, phosphorus, and the breakdown of nucleic acids to produce high levels of uric acid. Despite landmark chimeric antigen receptor (CAR) T-cell trials reporting TLS to be an uncommon adverse event, there is a lack of consensus on utilizing prophylactic allopurinol as a preventative strategy. Currently, there are no randomized trials that have assessed TLS as a primary endpoint with CAR T-cell recipients. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - February 1, 2024 Category: Hematology Authors: David Sicre, Shreya A Shah, Sila D Shalhoub, Katrina M Piedra, Jay Spiegel Tags: 632 Source Type: research
Direct LDL Cholesterol Assay vs. Estimated Equations in Patients With Hypertriglyceridemia or Low LDL Cholesterol Levels
Ann Lab Med. 2024 Jan 19. doi: 10.3343/alm.2023.0387. Online ahead of print.NO ABSTRACTPMID:38237928 | DOI:10.3343/alm.2023.0387 (Source: Annals of Laboratory Medicine)
Source: Annals of Laboratory Medicine - January 18, 2024 Category: Laboratory Medicine Authors: Jennifer Rodr íguez-Domínguez Álvaro Piedra-Aguilera Mar ía Martínez-Bujidos Susana Malumbres-Serrano Cristian Morales-Indiano Carla Fern ández-Prendes Source Type: research
Fluid balance, biomarkers of renal function and mortality in critically ill patients with AKI diagnosed before, or within 24 h of intensive care unit admission: a prospective study
CONCLUSIONS: In patients with pre-intensive care unit-onset AKI, positive fluid balance is associated with worse renal outcomes. Positive fluid balance and decline in biomarkers of renal function are related to increased mortality, thus in this subpopulation of critically ill patients, positive fluid balance is not recommended and renal function must be closely monitored.PMID:38189864 | DOI:10.1007/s40620-023-01829-z (Source: Journal of Nephrology)
Source: Journal of Nephrology - January 8, 2024 Category: Urology & Nephrology Authors: Frank Daniel Martos-Ben ítez Dail é Burgos-Aragüez Liselotte Garc ía-Mesa Versis Orama-Requejo Raysa Caridad C árdenas-González Juan Carlos Michelena-Piedra Judet Izquierdo-Casta ñeda Ernesto S ánchez-de-la-Rosa Olivia Corrales-Gonz ález Source Type: research
Breast Reconstruction after Blunt Breast Trauma: Systematic Review and Case Report Using the Ribeiro Technique
This study aimed to evaluate the evidence on breast reconstruction after blunt trauma associated with the use of a seat belt. Also, we describe the first case of breast reconstruction using the Ribeiro technique. In November 2022, a systematic search of MEDLINE, EMBASE, and Google Scholar databases was conducted. The literature was screened independently by two reviewers, and the data was extracted. Our search terms included breast, mammoplasty, blunt injury, and seat belts. In addition, we present the case of a woman with a left breast deformity and her reconstruction using the inferior Ribeiro flap technique. Six article...
Source: Archives of Plastic Surgery - December 25, 2023 Category: Cosmetic Surgery Authors: Horacio F Mayer Ren é M Palacios Huatuco Mariano F Ram írez Ignacio T Piedra Buena Source Type: research
