Sleep and Overactive Bladder in Parkinson's Disease
Urol Clin North Am. 2024 May;51(2):197-207. doi: 10.1016/j.ucl.2024.02.005. Epub 2024 Mar 10.ABSTRACTPatients with Parkinson's disease (PD) have disturbances in their bladder and sleep physiology that lead to nocturia and overactive bladder (OAB). These symptoms can be extremely bothersome and impact not only their quality of life (QoL) but also the QoL of their caretakers. We aim to highlight the changes in bladder and sleep physiology in PD and explore OAB/nocturia treatment strategies in this population.PMID:38609192 | DOI:10.1016/j.ucl.2024.02.005 (Source: The Medical Clinics of North America)
Source: The Medical Clinics of North America - April 12, 2024 Category: General Medicine Authors: Yu Zheng Anne P Cameron Source Type: research
Clinical course of mild-to-moderate idiopathic pulmonary fibrosis during therapy with pirfenidone: Results of the non-interventional study AERplus
CONCLUSIONS: The results of this study are in line with the established benefit-risk profile of pirfenidone. Therefore, pirfenidone can be considered a valuable treatment option to slow disease progression in mild-to-moderate idiopathic pulmonary fibrosis. NCT02622477.PMID:38608658 | PMC:PMC11014748 | DOI:10.1055/a-2267-2074 (Source: Pneumologie)
Source: Pneumologie - April 12, 2024 Category: Respiratory Medicine Authors: Jens Schreiber Wolfgang Sch ütte Wolfgang Koerber Bernd Seese Dirk Koschel Kathrin Neuland Christian Groh é Source Type: research
Sleep and Overactive Bladder in Parkinson's Disease
Urol Clin North Am. 2024 May;51(2):197-207. doi: 10.1016/j.ucl.2024.02.005. Epub 2024 Mar 10.ABSTRACTPatients with Parkinson's disease (PD) have disturbances in their bladder and sleep physiology that lead to nocturia and overactive bladder (OAB). These symptoms can be extremely bothersome and impact not only their quality of life (QoL) but also the QoL of their caretakers. We aim to highlight the changes in bladder and sleep physiology in PD and explore OAB/nocturia treatment strategies in this population.PMID:38609192 | DOI:10.1016/j.ucl.2024.02.005 (Source: The Urologic Clinics of North America)
Source: The Urologic Clinics of North America - April 12, 2024 Category: Urology & Nephrology Authors: Yu Zheng Anne P Cameron Source Type: research
Tailoring Transfection for Cardiomyocyte Cell Lines: Balancing Efficiency and Toxicity in Lipid versus Polymer-Based Transfection Methods in H9c2 and HL-1 Cells
In this study, we introduce meticulously crafted protocols to enhance the culture and transfection of HL-1 and H9c2 cells, emphasizing the reduction of cytotoxic effects while improving transfection efficiency. Through the examination of polymer-based and lipid-based transfection methods, we offer a comparative analysis that underscores the heightened efficiency and reduced toxicity of these approaches. Our research provides an extensive array of step-by-step procedures designed to foster robust cell cultures and outlines troubleshooting practices to rectify issues of low transfection rates. We discuss the merits and drawb...
Source: American Journal of Physiology. Heart and Circulatory Physiology - April 12, 2024 Category: Physiology Authors: Flobater I Gawargi Hamid R Shahshahan Paras K Mishra Source Type: research
The Association of Self-Reported Sleep and Circadian Measures with Glycemic Control and Diabetes Complications among Young Adults with Type 2 Diabetes
In conclusion, late bedtime on work/school days, rather than short sleep duration, daytime sleepiness, or poor sleep quality, was independently associated with loss of glycemic control in this longitudinal cohort of young adults with youth-onset type 2 diabetes.PMID:38607342 | DOI:10.1152/ajpheart.00550.2023 (Source: American Journal of Physiology. Heart and Circulatory Physiology)
Source: American Journal of Physiology. Heart and Circulatory Physiology - April 12, 2024 Category: Physiology Authors: Dorit Koren Kristen L Knutson Brian K Burke Kimberly L Drews Fida Bacha Lorraine Katz Marsha D Marcus Siripoom McKay Kristen Nadeau Babak Mokhlesi Source Type: research
