Winter Short: Storytelling, Featuring the Actin-Myosin Love Story | TAPP 130
Host Kevin Patton revisits someclassic segments from past episodes. In the first segment, he explains why he thinksstorytelling is the heart ofeffective teaching. Then. he tells a brief version of hisactin-myosin love story—a playfulanalogy to help students learn aboutmuscle contraction.00:00 | Introduction01:07 | Storytelling: The Heart of Teaching15:36| Sponsored by AAA, HAPI, and HAPS17:10 | Actin-Myosin Love Story27:58 | Staying Connected★ If you cannot see or activate the audio player, go to:theAPprofessor.org/podcast-episode-130.html🏅 Apply for your credential (badge/certificate) for listening to this epi...
Source: The A and P Professor - January 3, 2023 Category: Physiology Authors: Kevin Patton Source Type: blogs

Leadership lessons from Mayo Clinic [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! “In the emergency department I treat patients based upon my expert judgment. I can explain to you the sensitivities and specificities of the tests I order, I can detail the physiology and pathology involved in my differential diagnoses, and I can explain the rationale Read more… Leadership lessons from Mayo Clinic [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 1, 2023 Category: General Medicine Authors: Tags: Podcast Practice Management Source Type: blogs

Fight Aging! Newsletter, December 26th 2022
This article on senolytic therapies to selectively remove senescent cells in old tissues is in part a matter of Unity Biotechnology talking up their position. The company suffered from first mover disadvantage in bringing senolytic drugs into clinical development. The field has made progress very rapidly over the last decade, and startups founded even just a couple of years after Unity's launch benefited from greater knowledge and a selection of better technologies to work with. Still, one can be talking up one's position and also be right. The accumulation of senescent cells is profoundly harmful, a significant contributi...
Source: Fight Aging! - December 25, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Longer RNA Transcripts Exhibit Greater Alterations in Amount with Aging
We present three lines of evidence supporting the biological importance of the uncovered transcriptome imbalance. First, in vertebrates the length association primarily displays a lower relative abundance of long transcripts in aging. Second, eight antiaging interventions of the Interventions Testing Program of the National Institute on Aging can counter this length association. Third, we find that in humans and mice the genes with the longest transcripts enrich for genes reported to extend lifespan, whereas those with the shortest transcripts enrich for genes reported to shorten lifespan. Perhaps the most pressing ...
Source: Fight Aging! - December 23, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Winter Short: Students Perform Best with a Pre-Test | TAPP 129
In yet another of ourWinter Shorts episodes, Kevin Patton discusses his experience withPre-Tests as alearning tool—not simply an assessment tool. Surprisingly, the use of Pre-Testsimproved student scores on the regular tests.00:00 | Introduction01:07 | What is a Pre-Test?07:52 | Sponsored by AAA, HAPI, and HAPS09:25 | More Strategies for Learning the Skeleton15:13 | Staying Connected ★ If you cannot see or activate the audio player, go to:theAPprofessor.org/podcast-episode-129.html🏅 Apply for your credential (badge/certificate) for listening to this episode:theAPprofessor.org/podcast-episode-129.html/#badg...
Source: The A and P Professor - December 21, 2022 Category: Physiology Authors: Kevin Patton Source Type: blogs

Winter Short: Nine (or Ten) Strategies for Learning the Skeleton | TAPP 128
In another of ourWinter Shorts episodes, Kevin Patton discusses nine (or is it ten?)simple strategies for improvingstudent learning of the humanskeleton in the anatomy and physiology course.00:00 | Introduction01:07 | Strategies for Learning the Skeleton10:10 | Sponsored by AAA, HAPI, and HAPS11:43 | More Strategies for Learning the Skeleton20:30 | Staying Connected ★ If you cannot see or activate the audio player, go to:theAPprofessor.org/podcast-episode-128.html🏅 Apply for your credential (badge/certificate) for listening to this episode:theAPprofessor.org/podcast-episode-128.html/#badge⭐⭐⭐⭐ Please...
Source: The A and P Professor - December 8, 2022 Category: Physiology Authors: Kevin Patton Source Type: blogs

The Chemistry Clicked: Two NIGMS-Funded Researchers Receive Nobel Prize
Since its creation in 1962, NIGMS has supported the work of the recipients of 94 Nobel Prizes—44 in physiology or medicine and 50 in chemistry. NIGMS-funded investigators perform cutting-edge basic research that is foundational to understanding normal life processes and disease. Such important breakthroughs in chemistry and biology often fuel more focused research that, years later, leads to important medical advances or products such as medicines or biotechnology tools. Credit: Niklas Elmehed. The most recent NIGMS-supported Nobel laureates are Carolyn R. Bertozzi, Ph.D., the Anne T. and Robert M. Bass Professor in...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 7, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Tools and Techniques Cool Tools/Techniques Nobel Prize Profiles Source Type: blogs

Are these Hyperacute T-waves?
I received this ECG in a text message, with the message:" Hey, these look like hyperacute T waves to me, what do you think?  It ’s an intubated septic nursing home patient. "  " Here is her old ECG: "What do you think?Here is my response:" There is something wrong with this ECG.  It might be another case of pulse tapping artifact. Change the location of the limb Electrodes and repeat the EKG. All leads except lead I look bizarre. "So he repeated the ECG after moving the limb lead electrodes:Much less bizarre appearing, and without the suggestion of hyperacute T-wavesPulse Tapping ArtifactEver sin...
Source: Dr. Smith's ECG Blog - December 5, 2022 Category: Cardiology Authors: Steve Smith Source Type: blogs

How much “ pain ed ” do people need? And what to do when someone is not convinced …
This post has been a long time coming. There’s no doubt that giving explanations about pain mechanisms is common, and that we’ve (health professionals) been doing it a looooong time. Yes, way back to the 1970’s! In the early 1980’s when I started working in this field it was already commonplace to offer people an explanation for chronic pain (and to explain why some pains are such pains, while others bother us less – even when they involve the same degree of nociceptive input). Of course, way back then we used Gate Control Theory (GCT) to explain the distinction between hurt and harm, to explo...
Source: HealthSkills Weblog - November 27, 2022 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Clinical reasoning Education/CME Research Science in practice biopsychosocial Explain pain pain explanations PNE Therapeutic approaches Source Type: blogs

Winter Short: Mitochondria, Platelets, Golgi, & Green Pens TAPP 127
Episode 127 is one of ourwinter shorts, where I replay interesting segments from previous episodes. In this one, you ' ll hear about the role ofplatelets in immunity, how theGolgi apparatus gets its weird shape, exactlyhow hot mitochondria get, and why we may want to consider marking assignments and tests with agreen pen, rather than a red one.00:00 | Introduction01:07 | Mitochondria02:29 | Platelets07:15 | Sponsored by AAA, HAPI, and HAPS08:49 | Golgi Apparatus13:51 | Green Pens16:20 | Staying Connected ★ If you cannot see or activate the audio player, go to:theAPprofessor.org/podcast-episode-127.html🏅...
Source: The A and P Professor - November 18, 2022 Category: Physiology Authors: Kevin Patton Source Type: blogs

Implantable Device Adheres to Muscle, Treats Atrophy
This study by Dave Mooney and his group is a very elegant and forward-looking example of how this type of mechanotherapy could be used clinically in the future.” The MAGENTA device with its tough hydrogel adhesive surface (shown on the left) was implanted on a mouse’s calf muscle that in the atrophy model then was immobilized for a longer period of time to induce muscle wasting. Actuating the device by turning the electricity on lets it contract, generating mechanical stimulation to the underlying muscle, whereas turning the electricity off allows the device and muscle to relax (top row on the right). The pa...
Source: Medgadget - November 16, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Orthopedic Surgery Rehab muscle atrophy wyssinstitute Source Type: blogs

Post doctoral and doctoral opportunities at Basque Center on Cognition Brain and Language (San Sebasti án, Basque Country, Spain)
 FUNDED POSTDOCTORAL CANDIDATE POSITION – Signal Processing in Neuroimaging group at the BCBL- Basque Center on Cognition Brain and Language (San Sebasti án, Basque Country, Spain) www.bcbl.euINFORMATION ABOUT THE POSITION Position: PostdoctoralResearcher Profile: R2, Recognised Researcher (PhD holders or equivalent who are not yet fully independent) / R3, Established Researcher(Researchers who have developed a level of independence)Number of vacancies: 1Project: OpenLocation:  Spain> Donostia-San SebastianResearch Field: Cognitive NeuroscienceJob Statu...
Source: Talking Brains - November 9, 2022 Category: Neuroscience Authors: Greg Hickok Source Type: blogs

Does High Blood Pressure Make You Tired, Sleepy?
This article will help shed light on the link. Quick Summary There is a strong link between feeling tired or sleepy with high blood pressure due to underlying conditions or medication. Kidney disease, arterial disease, and sleep apnea are possible explanations for lethargy with hypertension. Proper treatment and control can reduce the risk of fatigue caused by elevated blood pressure. So, Does High Blood Pressure Make You Feel Tired, Sleepy, or Fatigued? Fatigue and high blood pressure are connected, but they could also be a symptom of underlying causes—for example, hypertension medication...
Source: The EMT Spot - November 8, 2022 Category: Emergency Medicine Authors: Michael Kutryk Tags: Guides Blood Pressure Source Type: blogs

I was shown this ECG without any information. What do you think?
I was shown this ECG; " Steve, what do you think of this? " :What is going on?I said: " This is pulse tapping artifact and a long QT "  Why did I say that?Whenever you see a very bizarre EKG, you should think about pulse tapping artifact.  This is when one of the limb lead electrodes is placed over an artery, especially when placed over a dialysis fistula.When you suspect this, your next task is look for the one lead among leads I, II, and III which is NOT bizarre.  Lead I in this ECG is not bizarre [though it does show a very long QT (or QU)].Leads I is formed by the right arm and left arm electro...
Source: Dr. Smith's ECG Blog - November 8, 2022 Category: Cardiology Authors: Steve Smith Source Type: blogs

Pathological VVI pacing pips DDD,.. one more time in the EP race !
This study reaffirmed the lack of appreciable hemodynamic and clinical benefits with DDD mode yet again.  We have also contributed a little on this issue. It was found cardiac failure in VVI pacing was not a real big issue in the long-term follow-up. We presented and published in world congrees of cardiology Dubai 2012, and Circulation journal.  How is that? A dual chamber pacer with AV synchrony fails to show a hemodynamic benefit? The answer is simple..VV desynchrony is a common denominator for both VVI and DDD pacers. Providing AV synchrony without VV synchrony doesn’t make real sense in the long term to ...
Source: Dr.S.Venkatesan MD - November 3, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Pace maker Tips and tricks Uncategorized pacemaker mode selection vvi vs ddd pacing Source Type: blogs