Wanted: Chemistry and Chemical Biology Program Director
We’re seeking a highly qualified scientist to serve as a program director in our Division of Pharmacology, Physiology, and Biological Chemistry (PPBC). This is a newly created position for the Division as it reorganizes into three Branches. Applicants should have significant interest and experience in the scientific areas comprising the newly formed Chemistry and Chemical Biology Branch. The purpose of the Branch is to foster meritorious research in chemical biology, synthetic biology, chemical catalysis and synthesis, carbohydrate chemistry, natural products, bioinorganic chemistry, and metabolic engineering. We seek...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - January 10, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Job Announcements Source Type: blogs
A Tongue Twister's Guide to Mastering Anatomy Pronunciation | Winter Shorts | TAPP 145
Episode 145 of The A&P Professor podcast is one of ourwinter shorts, where I replay interesting segments from previous episodes. In this one, you ' ll hear about the trials and tribulations of teaching and learningpronunciations of anatomy and physiology terminology. Including why the instructor is ALWAYS correct!00:00 | Introduction01:07 | Variations in Anatomy& Physiology Pronunciations10:24 | Say Anatomy& Physiology Terms Out Loud20:30 | Staying Connected★ If you cannot see or activate the audio player, go to:theAPprofessor.org/podcast-episode-145.html🏅 Apply for your credential (badge/certificate)...
Source: The A and P Professor - January 2, 2024 Category: Physiology Authors: Kevin Patton Source Type: blogs
Fight Aging! Newsletter, December 25th 2023
This study generates a comprehensive single-cell transcriptomic atlas of human atherosclerosis including 118,578 high-quality cells from atherosclerotic coronary and carotid arteries. By performing systematic benchmarking of integration methods, we mitigated data overcorrection while separating major cell lineages. Notably, we define cell subtypes that have not been previously identified from individual human atherosclerosis scRNA-seq studies.
Besides characterizing granular cell-type diversity and communication, we leverage this atlas to provide insights into smooth muscle cell (SMC) modulation. We integrate genome...
Source: Fight Aging! - December 24, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
D-Mannose Treatment Reduces Senescent Cell Burden in the Aging Bladder
Researchers here show that D-mannose treatment can upregulate autophagy in bladder and urinary tract epithelial cells, reducing inflammation and other cellular dysfunction. Like other approaches that increase autophagy, such as the use of mTOR inhibitors and calorie restriction, this appears to reduce the burden of cellular senescence over time in aged tissues. This likely results from a slowdown of the pace at which cells become senescent, allowing the immune system to catch up in its task of destroying lingering senescent cells. The end result of this improvement in tissue quality is a greater resistance to urinary tract...
Source: Fight Aging! - December 21, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Ginger Vieira – Exercise with Type 1 Diabetes
In conclusion, Ginger Vieira’s book, Exercise with Type 1 Diabetes (affiliate link), is a must-read for anyone with diabetes who wants to incorporate exercise into their daily routine.
Ginger’s expertise and personal experiences make this book a valuable resource for understanding the impact of exercise on blood sugar levels and managing diabetes effectively.
With practical tips and a supportive approach, Ginger empowers readers to take control of their health and enjoy the benefits of exercise. Don’t miss out on this concise and informative guide! ...
Source: Scott's Diabetes Blog - December 20, 2023 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs
Dissecting the Kenhub Atlas: Insights from Editor Mike Pascoe | TAPP 144
Mike Pascoe joins host Kevin Patton in Episode 144 to chat about Mike ' s experience in editing the newKenhub Atlas of Human Anatomy. We gobehind the scenes to see how this new kind of anatomy atlas was developed. Let ' s see how those decisions get made and how thelearning perspective gets incorporated into anatomy manuals. And we explorediverse representation in anatomy images and why we won ' t find anyeponyms in this atlas. We also have a brief remembrance of our friendDavid Allard.00:00 | Introduction00:45 | Remembering David Allard04:25 | Introducing Mike Pascoe06:12 | A New Take on the Human Atlas19:0...
Source: The A and P Professor - December 14, 2023 Category: Physiology Authors: Kevin Patton Source Type: blogs
The Most Overhyped Technologies in Healthcare
The hype about technological development in healthcare should not blind us in terms of the probabilities and possibilities of today’s healthcare and the future of medicine. To remain objective and conscious but still optimistic, let’s look at the most overhyped technologies and keep in mind the realistic development opportunities in healing.
You know the saying: the pessimist says the glass is half empty, the optimist says it is half full, and, well, the cynic asks who drank the other half? I’m truly an optimist – especially when it comes to the future of medicine and healthcare, but we need to ask the uncom...
Source: The Medical Futurist - December 5, 2023 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine 3d printing robotics virtual reality wearables GC1 hype organs Source Type: blogs
Is coronary dissection painful ?
Answer : Is the coronary dissection really painful ? As in most situations of scientific medicine, the answer to the question is, It “may or may not”. But, for some strange reason, it is more often painless . Mind you, even if it occurs, it is atypical, continuous, non-anginal if flow is unaffected, and not relieved by nitro-glycerine. This has important clinical significance , as many successfully lysed STEMI patient might have minimal segments of dissection/deep plaque fissures. , may be misdiagnosed as post infarct angina.
Spontaneous coronary dissection vs Iatrogenic dissection
SCAD is a rare , diffe...
Source: Dr.S.Venkatesan MD - December 3, 2023 Category: Cardiology Authors: dr s venkatesan Tags: acute aortic dissection acute coroanry syndrome Source Type: blogs
What happens to blood pressure when we stand up ?
Many times , an Innocuous question poses a real challenge, to our life time understanding of circulatory physiology.
Submit a form.
This question is very important , if we want to understand the true mechanism of postural hypotension, a commonest autonomic disorder in elderly (& also the newly recognised entity orthostatic hypertension)
Orthostatic hypotension is defined as a sustained drop of at least 20 mm Hg in systolic blood pressure (SBP) or 10 mm Hg in diastolic blood pressure (DBP) within 3-5 minutes of going from a supine to a standing position. In patients with associ...
Source: Dr.S.Venkatesan MD - November 29, 2023 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized bp response on standing hemodynamics of standing hypertesnion orthostatic hypertension orthostatic hypotension pots syndreome Source Type: blogs
An Aging Clock Derived from Images of the Lens of the Eye
In this study, we used informative lens photographs to generate LensAge as an innovative indicator to reveal aging status of lens based on deep learning (DL) models. Under ideal physiological conditions (both genetic and environmental), biological age should be synchronized with chronological age. While in reality, there are almost always differences between biological age and chronological age, which is considered to result from individually different aging processes. Therefore, we measured the difference between LensAge and chronological age as the LensAge index to assess an individual's aging rate relative to peers, and...
Source: Fight Aging! - November 22, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, November 13th 2023
This study investigated the correlation among muscle strength, working memory (WM), and cortical hemodynamics during the N-back task of memory performance, and further explored whether cortical hemodynamics during N-back task mediated the relationship between muscle strength and WM performance. We observed that muscle strength (particularly grip strength) predicted WM of older adults in this cross-sectional study, which validated our hypothesis and expanded on previous research findings. Studies demonstrated that grip strength predicted executive function decline in patients with mild cognitive impairment. Other cross-sect...
Source: Fight Aging! - November 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Immune System Mediates Some of the Benefits of Exercise
It is uncontroversial to point out that exercise is good for long-term health. It slows aging, reduces risk of age-related disease, reduces mortality. A mountain of evidence supports these assertions, both animal studies demonstrating causation, and any number of large human studies showing correlation. Exercise, like the practice of calorie restriction, produces sweeping changes in the operation of metabolism. Near everything is different, both in the short term following exercise, and over the long term when looking at differences between the biochemistry of a fit individual versus that a sedentary individual. This can m...
Source: Fight Aging! - November 10, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
A Nobel Discovery
by Gertrud U. Rey On October 2nd, 2023, the Nobel Assembly at Karolinska Institutet announced the award of the 2023 Nobel Prize in Physiology or Medicine to Katalin Karikó and Drew Weissman. The decision was based on a series of fundamental discoveries that led to the development of the COVID-19 messenger RNA (mRNA) vaccines. Katalin … A Nobel Discovery Read More » (Source: virology blog)
Source: virology blog - November 2, 2023 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey Drew Weissman Katalin Kariko modified nucleoside mRNA vaccine N1-methyl-pseudouridine Nobel Prize Source Type: blogs
The One Teaching Strategy That Will Fix Your Anatomy & Physiology Course | TAPP 143
In episode 143 ofThe A&P Professor podcast for anatomy and physiology faculty, host Kevin Patton uncovers the super-secret, single,ultimate teaching strategy you need to keep your course tuned up andeffective. He also revisits the " out there "transducer model of the brain and suggests a connection with a recent discovery supportingquantum wave activity in brain cell microtubules. Yes, quantum waves in the microtubules. Kevin also clarifies and expands on those wacky" extra " courses he described in Episodes 140 and 141.00:00 | Introduction00:51 | Clarifying Kevin ' s Wacky Supplemental Courses15:50 | Quantum Acti...
Source: The A and P Professor - November 2, 2023 Category: Physiology Authors: Kevin Patton Source Type: blogs
Helping Healthcare Professionals Evaluate AI Offerings
Steve Weber
AJ Grotto
The following is a guest article by Steve Weber, Professor of the Graduate School at UC Berkeley, and AJ Grotto, Director, Program on Geopolitics, Technology, and Governance at Stanford University
Generative artificial intelligence technologies promise to improve healthcare in large part by enabling healthcare professionals to utilize massive troves of health-relevant data. They will fuel improvements across the healthcare value chain, starting with a better understanding of physiology and disease, to efficiencies in disease management, treatment protocols, and even billing and reimbursement. The tech...
Source: EMR and HIPAA - October 31, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning EMR-EHR Health IT Company Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops Security and Privacy AJ Grotto Cybersecurity Data Breach Epic Epic EHR Generative AI Health Data Healthcare Mono Source Type: blogs
