Fight Aging! Newsletter, October 11th 2021
In conclusion, this study examined how age and the process of aging are associated with changes in the microbiome of the small intestine, using validated sampling and processing techniques. The most significant differences are higher relative abundance of the phylum Proteobacteria and decreased relative abundance of Bacteroidetes in older subjects when compared to the youngest group. The higher relative abundance of Proteobacteria appeared to affect other duodenal microbial taxa, leading to decreased microbial diversity and increased relative abundance of coliforms and of anaerobic bacteria. The small intestine is vital to...
Source: Fight Aging! - October 10, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Radiation Treatment Persistently Alters Heart Cell Function to Produce Benefits in Heart Failure Patients
This paper is interesting as a first step on the way to further research into compensatory therapies that can reduce the cardiac muscle dysfunction of heart failure. One-time radiation therapy appears to persistently change cardiomyocyte behavior via altered epigenetic regulation of notch signaling, leading to modestly improved heart tissue function. Perhaps this should be taken as supportive of efforts to more directly target this regulatory pathway in the aging heart via other means.
Cardiac radiotherapy (RT) may be effective in treating heart failure (HF) patients with refractory ventricular tachycardia (VT). T...
Source: Fight Aging! - October 5, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Online Testing Effectiveness Data | Turning My Gray Hair Brown | TAPP 102
Can you believe it? Even more questions about mywacky testing scheme are answered in this episode —this time regardingstats demonstrating effectiveness of these strategies. I also talk aboutgray hair turning brown, naturally, whywe do NOT want our students tomaster A&P concepts, and whywe want to become the hippocampus. One of theweirdest episodes yet!00:00 | Introduction00:42 | Growing in Kindness10;02 | Sponsored by AAA10:52 | We Are the Hippocampus17:03| Sponsored by HAPI17:46 | Turn My Gray Hair Brown22:39 | Sponsored by HAPS23:18 | Online Testing: Effectiveness Data50:16 | Staying Connected ★ If you ...
Source: The A and P Professor - October 5, 2021 Category: Physiology Authors: Kevin Patton Source Type: blogs
What is the Impact of Atrial fibrillation on blood pressure ? … It is also irregularly irregular !
Atrial fibrillation has a direct effect on systemic blood pressure as stroke volume swings from beat to beat because of changing RR Interval ( preload ). The variation in systolic pressure actually reflects not only the changing stroke volume but also the enhanced contractility of the ventricle to the preload( Frank-Starling principle ). The net effect is reflected in the pulse as an irregularly irregular pulse (Both rate and volume /Amplitude).* However, In severely dysfunctional ventricles this variation in systolic BP can be minimal. Also realize, If the preload is changing every beat, there is a considerable dynami...
Source: Dr.S.Venkatesan MD - October 3, 2021 Category: Cardiology Authors: dr s venkatesan Tags: Cardiology - Clinical Blood pressure in atrial fibillation cardiology research topic cardiology thesis topic pulse deficit Source Type: blogs
What is the effect of Atrial fibrillation on blood pressure ?
Atrial fibrillation has a direct effect on systemic blood pressure as stroke volume swings from beat to beat because of changing RR Interval ( preload ). The variation in systolic pressure actually reflects not only the changing stroke volume but also the enhanced contractility of the ventricle to the preload( Frank-Starling principle ). The net effect is reflected in the pulse as an irregularly irregular pulse (Both rate and volume /Amplitude).* However, In dysfunctional ventricles or in acute AF* this variation in systolic BP can be significant. Also realize, If the preload is changing every beat, there is a consider...
Source: Dr.S.Venkatesan MD - October 3, 2021 Category: Cardiology Authors: dr s venkatesan Tags: Cardiology - Clinical Blood pressure in atrial fibillation cardiology research topic cardiology thesis topic pulse deficit Source Type: blogs
Fight Aging! Newsletter, October 4th 2021
In conclusion, premature thymic involution and chronic inflammation greatly contribute to increased morbidity and mortality in CKD patients. Mechanisms are likely to be multiple and interlinked. Even when the quest to fountain of youth is a pipe dream, there are many scientific opportunities to prevent or to, at least in part, reverse CKD-related immune senescence. Further studies should precisely define most important pathways driving premature immune ageing in CKD patients and best therapeutic options to control them.
Extending Life Without Extending Health: Vast Effort Directed to the Wrong Goals
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Source: Fight Aging! - October 3, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Chronic Kidney Disease and an Accelerated Aging of the Immune System
In conclusion, premature thymic involution and chronic inflammation greatly contribute to increased morbidity and mortality in CKD patients. Mechanisms are likely to be multiple and interlinked. Even when the quest to fountain of youth is a pipe dream, there are many scientific opportunities to prevent or to, at least in part, reverse CKD-related immune senescence. Further studies should precisely define most important pathways driving premature immune ageing in CKD patients and best therapeutic options to control them. (Source: Fight Aging!)
Source: Fight Aging! - September 29, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Even MORE Test Answers | Normal Body Temperature? | TAPP 101
Have you ever really considered the actualmeaning that word "normal" in the context of teaching anatomy and physiology? Is it evenmeaningful at all? We explore that in the context ofhuman body temperature in Episode 101. And I give somepractical tips as we continue our conversation about myopen, online, randomized testing scheme.0:00:00 | Introduction0:00:47 | What Does Normal Mean?0:08:32 | Sponsored by AAA0:10:01 | What is Normal Body Temperature?0:27:21| Sponsored by HAPI0:29:13 | In Our Last Episode...0:32:20 | Sponsored by HAPS0:33:35 | Practical Tips on Testing0:52:39 | What About Lab Practicals?1:01:31 | Staying Con...
Source: The A and P Professor - September 21, 2021 Category: Physiology Authors: Kevin Patton Source Type: blogs
D-Cube syndrome : DES-Dengue-DAPT
Background
A 52-year-old diabetic woman who had undergone recent PCI with a DES developed a febrile illness which was diagnosed as Dengue fever. She has been taking DAPT (Dual antiplatelet) meticulously to maintain her stent. Now, her platelet count has dropped from 1.5 and subsequently to 1 lakh. She is asking now, whether to stop DAPT or not? What is the risk of stent occlusion if she stops?
The D³ cube syndrome
Infectious diseases rarely bother a cardiologist (maybe a few IE, myocarditis, etc). Now, a unique situation is emerging.
*Dengue affects 50-100 million people worldwide every year and one billion are ...
Source: Dr.S.Venkatesan MD - September 9, 2021 Category: Cardiology Authors: dr s venkatesan Tags: anti platelet drug antiplatelet drugs in dengue clopidogrel prasugrel ticagrelol in dengue fever dapt in dengue fever therapeutic issues in dengue and cad warfarin heparin in dengue Source Type: blogs
More Quizzing About Kevin's Wacky Testing Scheme | Book Club | TAPP 100
After getting somequestions after theprevious episode, host Kevin Patton continues his discussion of his wacky scheme ofopen online testing. Not unrelated is a new entry of an old book intoThe A&P Professor Book Club—it's Ken Bain's classic bookWhat The Best College Teachers Do. And we celebrate theone hundredth episode of this podcast!0:00:00 | Introduction0:00:42 | 100th Episode!0:09:40 | Book Club0:14:23 | Sponsored by AAA0:16:07 | But, But, But...0:29:00| Sponsored by HAPI0:30:32 | An Open Test for All Seasons0:58:58 | Sponsored by HAPS1:00:27 | Test Feedback1:19:16 | Staying Connected★ If you cannot see o...
Source: The A and P Professor - September 7, 2021 Category: Physiology Authors: Kevin Patton Source Type: blogs
More Quizzing About Kevin's Wacky Testing Scheme | Book Club | TAPP 100
After getting somequestions after theprevious episode, host Kevin Patton continues his discussion of his wacky scheme ofopen online testing. Not unrelated is a new entry of an old book intoThe A&P Professor Book Club—it ' s Ken Bain ' s classic bookWhat The Best College Teachers Do. And we celebrate theone hundredth episode of this podcast!0:00:00 | Introduction0:00:42 | 100th Episode!0:09:40 | Book Club0:14:23 | Sponsored by AAA0:16:07 | But, But, But...0:29:00| Sponsored by HAPI0:30:32 | An Open Test for All Seasons0:58:58 | Sponsored by HAPS1:00:27 | Test Feedback1:19:16 | Staying Connected★ If you cannot s...
Source: The A and P Professor - September 7, 2021 Category: Physiology Authors: Kevin Patton Source Type: blogs
