Fight Aging! Newsletter, October 24th 2022
This study shows the uncoupling of lifespan and healthspan parameters (aerobic fitness and spontaneous activity) and provides new insights into SIRT3 function in CR adaptation, fuel utilization, and aging.
HDL Level, Age, and Smoking are the Largest Determinants of Mortality Risk in Old People
https://www.fightaging.org/archives/2022/10/hdl-level-age-and-smoking-are-the-largest-determinants-of-mortality-risk-in-old-people/
An interesting epidemiological study here stratifies the contributions of various metrics to mortality in later life, age 70 and older. The authors find that the largest effects arise...
Source: Fight Aging! - October 23, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Pee Episode | Teaching Urinary & Renal Concepts | TAPP 125
Teachingrenal anatomy& physiology istricky and sometimesdifficult. InThe Pee Episode I ' ll tell you how Iknow that for sure. Plus, I ' ll share some possiblestrategies for providing the clarity needed to avoid confusion and that unhelpful kind of frustration that sometimes accompanies the renal module in our course. And there ' sa song from Greg Crowther!00:00 | Introduction00:47 | Adventures With Tarzan06:51 | Making Heads or Tails or Loops20:32 | Sponsored by AAA21:31 | Big Picture of Renal A&P32:27 | Pee Values With Greg Crowther34:34 | Sponsored by HAPI35:39 | Scared?41:39 | Sponsored by HAPS42:33 | Urin...
Source: The A and P Professor - October 21, 2022 Category: Physiology Authors: Kevin Patton Source Type: blogs
A View of the Road Ahead to Viable Xenotransplantation
In principle, engineering pig organs to survive in humans is a viable project for this age of biotechnology. Pig organs are the right size, and strategies exist to address the known issues in rejection of tissues, transfer of retroviruses, and the like. An entire industry is coming into being based on enabling cells and tissues from one individual to be introduced into another without rejection. Much of the work needed to make that possible between individuals of the same species also enables transplantation between species.
In a world in which organs fail, and transplants are in limited supply, there are several ro...
Source: Fight Aging! - October 20, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Anatomy & Physiology: Combo or Split? | Journal Club with Krista Rompolski | TAPP 124
Dr. Krista Rompolski joins us for aJournal Club episode discussing a study regarding whether it ' s best to have aseparate anatomy course followed by aphysiology course, or tocombine anatomy& physiology into an integrated two-semester sequence. We ' ve all considered this question, haven ' t we? Now we have somedata to discuss!00:00 | Introduction00:45 | Journal Club02:46 | Summary of Article07:23 | Long-Term Retention Sucks Either Way19:39 | Sponsored by AAA20:35 | Cover Everything?33:33 | Sponsored by HAPI34:44 | Detailing the Level of Detail50:00 | Sponsored by HAPS50:48 | What ' s Best?54:27 | Stayin...
Source: The A and P Professor - October 5, 2022 Category: Physiology Authors: Kevin Patton Source Type: blogs
Fonts, Syllabi, and Poop | TAPP 123
Host Kevin Patton revisits the concept of using thesyllabus and othercourse documents to build apositive and productive course culture.Poop—it ' s everywhere! Does thefont or typeface we use affect students —especially regardinglearning andmemory? We look for answers in this episode!00:00 | Introduction00:52 | Revisiting the Syllabus16:28 | Poop. Poop. Poop.19:00 | Sponsored by AAA19:59 | Fonts Are Important in Teaching& Learning30:54 | Sponsored by HAPI31:57 | Desirably Difficult Reading?42:00 | Sponsored by HAPS43:00 | Fluent& Dysfluent Fonts56:12 | Staying Connected ★ If you cannot see or ac...
Source: The A and P Professor - September 20, 2022 Category: Physiology Authors: Kevin Patton Source Type: blogs
Fight Aging! Newsletter, September 19th 2022
Conclusion
Use of the Khavinson peptides and melatonin in combination in this way, at this dose, negatively impacts the thymus, producing a reduction in active tissue and increase in atrophy to fatty tissue. The degree to which this atrophy occurred is greater than one would expect to take place over nine months of aging at this stage of life.
Why did this outcome occur, given the animal studies showing thymic regrowth, and the studies showing reduced later life mortality following use of thymogen? We can only speculate. Firstly, the dose makes the poison, and the dosing here may have been too high, too frequ...
Source: Fight Aging! - September 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
In the Matter of Human Longevity There Will Be Opportunists and Alchemists
I suspect that a sizable, earnest community of opportunists and alchemists focused on anti-aging and longevity will continue to exist even as we transition from an era in which the only approaches to aging (beyond exercise and calorie restriction) were snake oil, the only service providers frauds, to an era in which therapies to slow aging and produce rejuvenation actually exist and are robustly proven to do what they say on the label. Will reliable, low-cost ways to measure biological age drive out the true believers who try whatever intervention is hyped, fail to gain scientific understanding, and fail to use adequate me...
Source: Fight Aging! - September 16, 2022 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Allostatic Load Correlates with Risk of Age-Related Hearing Loss
Measures of aging tend to correlate with one another in any given study population. If someone is more affected by aging, then all of his or her physiology tends to be more functionally impacted. Thus it isn't always clear as to what can be learned from epidemiology of the sort noted here. One has to look closely at the details. Nonetheless, researchers here show that allostatic load over the course of aging correlates with the risk of suffering hearing loss. Allostatic load is a measure of stress and divergence from optimal function in the systems of the body, more or less, as determined by a range of biomarkers relating ...
Source: Fight Aging! - September 14, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Motion Sensors to Detect Age-Related Disease
Researchers at the University of Bern in Switzerland have developed a motion tracking system that is intended to assist in detecting age-related disease in elderly people. The system could be installed in someone’s home or in assisted-living facilities, and consists of a series of motion sensors that can monitor for signs of unusual movement. The system can inform caregivers if an emergency arises, such as a fall, which can be detected when someone does not return to their bed at night or is stationary for a long period, for example. However, the researchers also envisage it as helping to provide early detection for a va...
Source: Medgadget - September 9, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Geriatrics Rehab unibern Source Type: blogs
Teaching Human Reproduction | A Chat with Margaret Reece | TAPP 122
VeteranA&P educator andreproduction researcherDr. Margaret Reece joins host Kevin Patton to talk about challenges of teaching humanreproduction and development. Reece also briefly discusses heronline resources (MedicalScienceNavigator.com) and her experiences in helpingoverwhelmed A&P students succeed in their studies.00:00 | Introduction00:43 | Reproductive Biology08:13 | Sponsored by AAA08:58 | Ultrasound& Reproductive Biology20:25 | Sponsored by HAPI21:13 | Basic Science35:27 | Sponsored by HAPS36:33 | Medical Science Navigator50:19 | Staying Connected ★ If you cannot see or activate the aud...
Source: The A and P Professor - September 8, 2022 Category: Physiology Authors: Kevin Patton Source Type: blogs
Acute chest pain and a bizarre ECG
Written by Pendell MeyersA middle aged adult presented with acute undifferentiated chest pain.Here is his ECG at triage:What do you think?I sent this ECG with no clinical information to Dr. McLaren, who replied simply " Artifact " . He is referring to an artifactual ECG pattern that corresponds with the cardiac cycle which is known as " arterial pulse tapping artifact. " See the discussion and links at the end of the post for more information, but this phenotype of ECG artifact is not yet well understood (to my knowledge). In some cases, it has been attributed to placement of an electrode near a pulsing anatomic...
Source: Dr. Smith's ECG Blog - August 26, 2022 Category: Cardiology Authors: Pendell Source Type: blogs
When medicine surrenders to the body
I still get chills thinking about the moment I decided to go to medical school. I was bored in my college physiology class, watching the minute hand on the round lecture hall clock. There were just a few minutes remaining in the class, and students were starting to pack up. The professor, Dr. Adams, said,
Read more…
When medicine surrenders to the body originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - August 25, 2022 Category: General Medicine Authors: Eleanor Tanno, MD Tags: Physician Critical Care Source Type: blogs
The Poop Episode | Using Fecal Changes to Monitor Health | TAPP 121
InThe Poop Episode, host Kevin Patton applies stories from his experiencemonitoring digestive health in zoo and circus animals to human anatomy and physiology. We explore thefrequency of defecation, andhow to read poop for common health issues. This is the episode that tells you how toget an elephant to poop on command!00:00 | Introduction01:08 | Getting Our 5#!+ in Order07:42 | Zookeepers Know Their 5#!+23:13 | Sponsored by AAA24:18 | No Poop July30:58 | Sponsored by HAPI32:07 | Poop Reading42:12 | Sponsored by HAPS42:58 | We All Need to Know Our 5#!+46:24 | Staying Connected★ If you cannot see or activate the...
Source: The A and P Professor - August 25, 2022 Category: Physiology Authors: Kevin Patton Source Type: blogs
Trial By Error: Todd Davenport on Post-Exertional Symptom Exacerbation in Long Covid and ME/CFS
By David Tuller, DrPH Todd Davenport is a professor of physical therapy at University of the Pacific in Stockton, California. He is also part of a research team from Workwell Foundation, an exercise physiology center in Ripon, California, that pioneered the use of 2-day cardiopulmonary exercise testing (CPET) to document the core ME and ME/CFS symptom […] (Source: virology blog)
Source: virology blog - August 23, 2022 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs
Fight Aging! Newsletter, August 15th 2022
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - August 14, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
