Try these two simple papers, that could fetch you a “ Nobel prize in Medicine or Economics ” for sure !
This piece of article by Mr. Arun Maira,(The Pakistan-born British Indian ex-planning commission member) is a real eye-opener in the manner we have understood science. All socially conscious scientists must-read. (If properly appreciated, the 15 minutes  you are going to spend on this is worth the time of one full semester in economics at a top-notch university ) Was the past perfect?  & will the future be tense? No is the answer. Heartening to note, Noble prizes are increasingly given for some soul-searching simple researches. Complex research methodology is looked down on, especially in economics. Contributors ...
Source: Dr.S.Venkatesan MD - October 19, 2021 Category: Cardiology Authors: dr s venkatesan Tags: bio ethics comparative research cost effectiveness in medical research Epistemology health economics medical economics medicial education nobel prize deserving concepts in economics noble prize in medicine economics research topics in ec Source Type: blogs

Fight Aging! Newsletter, October 4th 2021
In conclusion, premature thymic involution and chronic inflammation greatly contribute to increased morbidity and mortality in CKD patients. Mechanisms are likely to be multiple and interlinked. Even when the quest to fountain of youth is a pipe dream, there are many scientific opportunities to prevent or to, at least in part, reverse CKD-related immune senescence. Further studies should precisely define most important pathways driving premature immune ageing in CKD patients and best therapeutic options to control them. Extending Life Without Extending Health: Vast Effort Directed to the Wrong Goals https://ww...
Source: Fight Aging! - October 3, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Friday Feature: Learn Everywhere
Colleen HroncichWelcome to the Friday Feature, a new series on Cato at Liberty that ’s going to highlight interesting stories in the education space. Innovative schools; exciting educational programs; inspiring students, parents, and teachers—all these and more. This first post looks at New Hampshire’s Learn Everywhere program since one theme of the Friday Feature will be tha t children can—and do—learn everywhere.“Commissioner, you have to help us. The school closes at 9 p.m., we need it open until 10 p.m. ”Thissimple request by a member of a New Hampshire high school robotics team was th...
Source: Cato-at-liberty - October 1, 2021 Category: American Health Authors: Colleen Hroncich Source Type: blogs

Borrowing Concepts from Particle Physics to Better Frame the Mechanisms of Aging
An interesting idea is put forward in this open access paper, aimed at producing a greater and more useful unity of thought about the processes of aging. It is certainly the case that the field lacks a common conceptual foundation to build upon when it comes to working towards a better understanding of the mechanisms of aging. Hence the many theories of aging, focusing on quite different areas of molecular biology and evolutionary biology, and the persistent debate over whether aging is an evolved epigenetic program of late life dysfunction (the minority position), or an accumulation of damage that falls outside selection ...
Source: Fight Aging! - September 29, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Relative risk perception and public investment
 Motor vehicles are not quite in the top 10 causes of death in the U.S.The way the CDC categorizes causes of death, unintentional injuries are number 3, about 173,000 deaths per year, and motor vehicle-related injuries constitute about 1/3 of those. If you were to extract those 40,000+ motor vehicle deaths they would probably be at about #11. (This data is from 2019, and for 2020 Covid has undoubtedly bumped up cause number 9, " influenza and pneumonia, from 9 to 3 making unintentional injuries number 4, but we can hope this is temporary.) However, unlike the other leading causes of death, which disproportionatel...
Source: Stayin' Alive - September 21, 2021 Category: American Health Source Type: blogs

More Laughing, More Thinking
By KIM BELLARD There was a lot going on this week, as there always is, including the 20th anniversary of 9/11 and the beginning of the NFL season, so you may have missed a big event: the announcement of the 31st First Annual Ig Nobel Awards (no, those are not typos).   What’s that you say — you don’t know the Ig Nobel Awards?  These annual awards, organized by the magazine Annals of Improbable Research, seek to: …honor achievements that make people LAUGH, then THINK. The prizes are intended to celebrate the unusual, honor the imaginative — and spur people’s interest in scie...
Source: The Health Care Blog - September 15, 2021 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice Research health research Ignobel Kim Bellard Source Type: blogs

Fight Aging! Newsletter, September 13th 2021
In this study, mature DCs (mDCs), generated from the GM-CSF and IL-4 induced bone marrow cells, were intravenously injected into wild-type mice. Three days later, assays showed that the mDCs were indeed able to return to the thymus. Homing DCs have been mainly reported to deplete thymocytes and induce tolerance. However, medullary TECs (mTECs) play a crucial role in inducing immune tolerance. Thus, we evaluated whether the mDCs homing into the thymus led to TECs depletion. We cocultured mDCs with mTEC1 cells and found that the mDCs induced the apoptosis and inhibited the proliferation of mTEC1 cells. These effects were onl...
Source: Fight Aging! - September 12, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Altos Labs Formed to Work on the Treatment of Aging
It remains to be seen as to whether Altos Labs is the new, large venture that patient advocates for the treatment of aging have been alluding to cryptically in recent months. It is apparently backed by a number of the high net worth individuals in the Left Coast business and philanthropy communities who are known to have a growing interest in the application of biotechnology to aging. Sadly, recent history suggests we should not expect much from such initiatives. Neither the Ellison Medical Foundation nor Calico Labs have done more than take on more of the same fundamental research into the progression of aging that is car...
Source: Fight Aging! - September 6, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Navajo Students Engage With Public Health Research Through NARCH
Navajo students are contributing to public health efforts in diabetes, COVID-19, domestic violence, and maternal and child health through the Navajo Native American Research Center for Health (NARCH) Partnership. “Our goal is to really enhance the educational pathways available to Navajo students from high school to graduate school and beyond,” says Mark Bauer, Ph.D., a co-director of the Navajo NARCH Partnership and professor at Diné College—a tribal college on the Navajo Nation. (Diné means “the people” and is how Navajo people refer to themselves in their native language.) An Introduction to Public He...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 25, 2021 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist COVID-19 Training Source Type: blogs

How To Slow Down Our Perception of Time
Time has been a great mystery for many philosophers, mathematicians, physicists, and other great thinkers. We often ask ourselves, “Where has the time gone?” As we watch our parents age and our younger relatives grow up, time can be both painful and redeeming. Time is a key component of our daily lives, a guiding force for our behavior. Adults seem to obsess over time that has passed swiftly and recall the days of long summers as a child. There is an ever-present nostalgia for being young again – a period when time seemed to move slowly, languorously. Research suggests that older people underestimate how much time ha...
Source: PickTheBrain | Motivation and Self Improvement - August 4, 2021 Category: Consumer Health News Authors: David Kirichenko Tags: featured happiness productivity tips psychology self-improvement perception of time Source Type: blogs

Shift Happens
Dataset shift can thwart the best intentions of algorithm developers and tech-savvy clinicians, but there are solutions.John Halamka, M.D., president, Mayo Clinic Platform, and Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform, wrote this article.Generalizability has always been a concern in health care, whether we ’re discussing the application of clinical trials or machine-learning based algorithms. A large randomized controlled trial that finds an intensive lifestyle program doesn’t reduce the risk of cardiovascular complications in Type 2 diabetics, for instance, suggests the...
Source: Life as a Healthcare CIO - July 28, 2021 Category: Information Technology Source Type: blogs

Taking Down the Fences that Divide Us
Innovation in healthcare requires new ways to think about interdisciplinary solutions.Paul Cerrato, senior research analyst and communications specialist, Mayo Clinic Platform and John Halamka, M.D., president, Mayo Clinic Platform, wrote this article.During the 10 years we have worked together, John and I have written often about the power of words liketransformation, optimism, cynicism, and misdiagnosis. Another word that needs more attention is “interdisciplinary.” It’s been uttered so many times in science, medicine, and technology that it’s lost much of its impact.  We all give lip service to the ide...
Source: Life as a Healthcare CIO - July 19, 2021 Category: Information Technology Source Type: blogs

On the bias of science: part whatever
Okay, I hope I ' ve swept away enough of the underbrush to get to the tall trees. The basic summary is that it can matter who ' s paying for research, and certainly if a corporate sponsor stands to benefit from a particular outcome a study is more likely to get that outcome. I should have mentioned that this is supported by head-to-head comparisons: evaluations of the same therapeutic modality tend to be more positive when sponsored by the manufacturer than by government. However, the way government funding works, government-sponsored investigators are independent and there is no discernible " government agenda " for resea...
Source: Stayin' Alive - July 15, 2021 Category: American Health Source Type: blogs

Up, Please
By KIM BELLARD When I think of elevator operators, I think of health care. Now, it’s not likely that many people think about elevator operators very often, if ever.  Many have probably never seen an elevator operator.  The idea of a uniformed person standing all day in an elevator pushing buttons so that people can get to their floors seems unnecessary at best and ludicrous at worse.  But once upon a time, they were essential, until they weren’t.  Healthcare, don’t say you haven’t been warned.  Elevators have been around in some form for hundreds of years, and by the 19th century were using steam o...
Source: The Health Care Blog - July 13, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Tech Health Technology elevator operators elevators Kim Bellard Source Type: blogs

On the bias of science: Part One
It seems that many people have some fundamental misconceptions about the nature of the scientific enterprise. It is obviously an institution with some flaws -- it ' s a human endeavor and humans are flawed. One of its strengths however, is a proclivity for self-examination. Most errors get corrected reasonably soon, and the culture, norms and policies of scientific institutions have tended to change for the better over time. (Past results are no guarantee of future performance.)Here are some facts that I know because I am inside it. I am on the faculty of a school of public health, which is associated with a medical school...
Source: Stayin' Alive - July 8, 2021 Category: American Health Source Type: blogs