The OMICS Universe And Its Future
The OMICS acronym crawled into the hive mind of the life science community as the Marvel universe onto the movie screens: slowly but successfully. Genomics, transcriptomics, proteomics, metabolomics, methylomics or surfaceomics occupy a growing field of research in systems biology lately. It will be an even more significant strand in the future with practical ramifications, such as transcriptomic tests for disease risks. Thus, it is recommended to get familiar with the OMICS universe. Here’s a glimpse of it.
Systems biology and the messenger game
When I was in fourth grade, a fun game sometimes referred to as the ‘...
Source: The Medical Futurist - January 5, 2019 Category: Information Technology Authors: nora Tags: Biotechnology Future of Medicine big data biology cancer clinical research genetics genomics metabolome metabolomics precision medicine proteome proteomics systems biology transcriptome transcriptomics treatment Source Type: blogs
The OMICS Universe And Its Future
The OMICS acronym crawled into the hive mind of the life science community as the Marvel universe onto the movie screens: slowly but successfully. Genomics, transcriptomics, proteomics, metabolomics, methylomics or surfaceomics occupy a growing field of research in systems biology lately. It will be an even more significant strand in the future with practical ramifications, such as transcriptomic tests for disease risks. Thus, it is recommended to get familiar with the OMICS universe. Here’s a glimpse of it.
Systems biology and the messenger game
When I was in fourth grade, a fun game sometimes referred to as the ‘...
Source: The Medical Futurist - January 5, 2019 Category: Information Technology Authors: nora Tags: Biotechnology Future of Medicine big data biology cancer clinical research genetics genomics metabolome metabolomics precision medicine proteome proteomics systems biology transcriptome transcriptomics treatment Source Type: blogs
Medical Video Game Guru: Interview with Sam Glassenberg, Level Ex CEO
Sam Glassenberg has spent his career in the video game industry, and now is on a mission to bring the leading edge of video game technology into healthcare. Sam is the founder and CEO of Level Ex, an award winning company making professional video games for doctors. Before Level Ex, Sam was CEO of a leading independent game publisher in Hollywood, led the DirectX team at Microsoft, and has been pushing limits in the gaming industry. Sam has an M.S. in Computer Science and Graphics from Stanford University, and a B.S. in Computer Engineering from the University of Illinois. I met Sam at the recently concluded TEDMED 2018 a...
Source: Medgadget - December 27, 2018 Category: Medical Devices Authors: Tom Fowler Tags: Education Exclusive Medicine Society Surgery Source Type: blogs
Fight Aging! Newsletter, December 17th 2018
In this study, we found that TNF-α resulted in an impairment of autophagic flux in microglia. Concomitantly, an increase of M1 marker expression and reduction of M2 marker expression were observed in TNF-α challenged microglia. Upregulation of autophagy via serum deprivation or pharmacologic activators (rapamycin and resveratrol) promoted microglia polarization toward M2 phenotype, as evidenced by suppressed M1 and elevated M2 gene expression, while inhibition of autophagy with 3-MA or Atg5 siRNA consistently aggravated the M1 polarization induced by TNF-α.
Moreover, Atg5 knockdown alone was sufficient to trigger...
Source: Fight Aging! - December 16, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Designer Babies: A Dystopian Sidetrack of Gene Editing
A Chinese scientist shocked the scientific community a couple of days ago with the announcement of having modified the very blueprint of life. If his claims are true, he tried to bestow two baby girls the ability to resist possible future infections with HIV. The outrage shows that humanity is not prepared to utilize the power of gene editing on embryos yet. We have no idea about the biological consequences, and we haven’t tackled the necessary legal and ethical issues.
Genes to become toys of the “Gods”?
Humanity has come a long way since Aldous Huxley pinned down how methods of genetic engineering, biological cond...
Source: The Medical Futurist - December 15, 2018 Category: Information Technology Authors: nora Tags: Bioethics Future of Medicine Genomics designer babies designer baby Gene gene editing genes Genome genome sequencing Health Healthcare healthcare system Innovation technology Source Type: blogs
A Selection of Opposing Views on Cryonics
Cryopreservation via a cryonics provider, such as Alcor or the Cryonics Institute in the US, is presently the only option available to the billions who will age to death prior to the advent of a comprehensive package of rejuvenation therapies. Sadly, it is not yet a well-developed industry, operating at scale. The technology exists to vitrify people immediately following clinical death, preserving the fine structure of brain tissue if the vitrification process is of sufficiently high quality, but very few people choose to take advantage of this opportunity. Every year, tens of millions go to oblivion rather than chose the ...
Source: Fight Aging! - December 11, 2018 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
POSTDOCTORAL POSITIONS at the BCBL- Basque Center on Cognition Brain and Language (San Sebasti án, Basque Country, Spain) www.bcbl.eu (Center of excellence Severo Ochoa)
The Basque Center on Cognition Brain and Language (San Sebasti án, Basque Country, Spain) offers three postdoctoral positions in three main broad areas or research:(1)-Language, reading and developmental disorders: How language acquisition, comprehension, production, and reading take place in the human brain. Special attention will be paid to language disorders and the development of computerized tools for their early diagnosis and treatment.(2)-Multilingualism and second language learning: The cognitive and brain mechanisms of language acquisition and processing in a second language. Special attention will be paid to mul...
Source: Talking Brains - November 26, 2018 Category: Neuroscience Authors: Greg Hickok Source Type: blogs
Fight Aging! Newsletter, November 26th 2018
This study is the culmination of a decade of research that has repeatedly demonstrated that this vaccine can effectively and safely target in animal models what we think may cause Alzheimer's disease. I believe we're getting close to testing this therapy in people."
Although earlier research established that antibodies significantly reduce amyloid buildup in the brain, researchers needed to find a safe way to introduce them into the body. A vaccine developed elsewhere showed promise in the early 2000s, but when tested in humans, it caused brain swelling in some patients. The new idea was to start with DNA coding for...
Source: Fight Aging! - November 25, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Can Systems Analysis Approaches Provide Insight into the Mechanisms of Aging?
Given enough data from enough old people, to what degree could modern approaches to information processing be used to derive useful information about the underlying mechanisms of aging? Such as which of the varied collection of causes and consequences involved in the biochemistry of aging are more important, how they are connected to one another, and so forth. On the one hand it seems plausible that something can be learned here, but on the other hand it seems unlikely to be as effective an approach as selectively interfering in specific mechanisms in order to observe the outcome in animal studies.
So far near all o...
Source: Fight Aging! - November 19, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
AI Doesn ’ t Ask Why — But Physicians And Drug Developers Want To Know
We describe phenomena using science, which gives us a sense of understanding and structure – yet we often lack actual understanding about what we’re observing, or why our treatments work. We have scientific explanations that may appear solid at first glance, but are flimsy upon closer inspection. More commonly, I imagine, we rely on scientific explanations as heuristics to enable us to get through our days, as a scaffold upon which to organize our information.
I suspect AI is viscerally uncomfortable, and challenging to apply to clinical care or drug discovery (see part 2), because of the psychological importance and c...
Source: The Health Care Blog - November 16, 2018 Category: Consumer Health News Authors: matthew holt Tags: Artificial Intelligence Pharmaceuticals Physicians AI David Shaywitz Health Tech Source Type: blogs
An interview with Sunil Krishnan, new co-EiC of Cancer Nanotechnology
As you can read about here, we are delighted to welcome Sunil Krishnan of MD Anderson, Tyler, Texas, as a new co-Editor-in-Chief of Cancer Nanotechnology. Sunil will join existing Editors-in-Chief Fred Currell, Dalton Cumbrian Facility, University of Manchester, UK, and Steve Curley, CHRISTUS Trinity Mother Frances, Texas, in helping to make Cancer Nanotechnology a premiere venue for research of its kind.
We caught up with Sunil to find out a bit more about him, his research and how he feels about his new role on the journal.
Sunil Krishnan; image courtesy of MD Anderson
Sunil, congratulations on becoming an EiC of Canc...
Source: BioMed Central Blog - November 6, 2018 Category: General Medicine Authors: Matthew Smyllie Tags: Health Medicine Open Access Publishing cancer nanotechnology interview Source Type: blogs
An interview with Sunil Krishnan, new co-EiC of Cancer Nanotechnology
As you can read about here, we are delighted to welcome Sunil Krishnan of MD Anderson, Houston, Texas, as a new co-Editor-in-Chief of Cancer Nanotechnology. Sunil will join existing Editors-in-Chief Fred Currell, Dalton Cumbrian Facility, University of Manchester, UK, and Steve Curley, CHRISTUS Trinity Mother Frances, Texas, in helping to make Cancer Nanotechnology a premiere venue for research of its kind.
We caught up with Sunil to find out a bit more about him, his research and how he feels about his new role on the journal.
Sunil Krishnan; image courtesy of MD Anderson
Sunil, congratulations on becoming an EiC of Ca...
Source: BioMed Central Blog - November 6, 2018 Category: General Medicine Authors: Matthew Smyllie Tags: Health Medicine Open Access Publishing cancer nanotechnology interview Source Type: blogs
