Microfluidics and AI Microscopy for Hemoglobin Measurements
In this study, we demonstrate that the applicability of a system originally designed for the purposes of imaging can be extended towards the performance of biochemical tests without any additional modifications to the hardware unit, thereby retraining the cost and laboratory footprint of the original device,” said Srinivasan Kandaswamy, a researcher involved in the study. The system consists of a microfluidic chip onto which a small-volume blood sample is loaded. The chip runs a sodium lauryl sulfate assay to detect hemoglobin within the sample. The chip can then be viewed using a microscope with automatic AI imag...
Source: Medgadget - February 25, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Anesthesiology Cardiology Critical Care Emergency Medicine Military Medicine Pediatrics Surgery Sigtuple Source Type: blogs

1896 – The Birth of Radiology
By SAURABH JHA and JEANNE ELKIN Mr. Smith’s pneumonia was clinically shy. He didn’t have a fever. His white blood cells hadn’t increased. The only sign of an infection, other than his cough, was that his lung wasn’t as dark as it should be on the radiograph. The radiologist, taught to see, noticed that the normally crisp border between the heart and the lung was blurred like ink smudged on blotting paper. Something that had colonized the lungs was stopping the x-rays.  Hundred and twenty-five years ago, Wilhelm Conrad Roentgen, a German physicist and the Rector at the University of Wurzburg, made an acci...
Source: The Health Care Blog - February 19, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Medical Practice Physicians RogueRad jeanne elkin Radiology Saurabh Jha Wilhelm Roentgen Source Type: blogs

PhD Student Positions in Speech Neuroscience - Univ. of South Carolina
  Department of Communication Sciences and Disorders  PhD Student Positions in Speech Neuroscience  The Speech Neuroscience Lab at the University of South Carolina is inviting highly-motivated students with interest in research on neuroscience of speech to apply for our PhD program. The PhD degree prepares professionals for academic careers with emphasis on research and the scholarly study of the science of human speech production system and its disorders. Doctoral students will complete their research training under direct mentorship, regularly participate in laboratory activities and pu...
Source: Talking Brains - February 18, 2021 Category: Neuroscience Authors: Greg Hickok Source Type: blogs

Better Get Your Quantum Computer
By KIM BELLARD By all rights, I should be writing about the battle between Reddit forum WallStreetBets and Wall Street hedge funds. Depending on one’s point of view, it’s hilarious, frightening, or a searing indictment on stock trading – maybe all three.  But I’m going to let Elon Musk and Elizabeth Warren handle that one.  Instead, I want to talk about quantum computing – and why healthcare needs to be looking ahead to it. Let’s start with this: for the low, low price of $5,000, you could have your very own quantum computer.  Spin Q Technology, a Chinese company, has recently introduced its Sp...
Source: The Health Care Blog - February 4, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Tech Health Technology Kim Bellard quantum computer Source Type: blogs

History of cardiology : Robert F Rushmer, a cardiac scientist par excellence .
Few individual’s works mattered more than others in the field of cardiology. Here was a man born in Utah, studied at Rush university trained in Mayo, settled in Seattle as a pediatrician. But his passion drove him to become a specialist cardiac physiologist with an urge to find the answers to all those lingering queries that arise as a practicing clinical cardiologist.  He built an exclusive animal lab to study the mechanics and physics of circulation and cardiac pumps.   He can be called new age, Harvey. He seemed to always bother, how is it that the 6 liters of blood traverse from he...
Source: Dr.S.Venkatesan MD - February 1, 2021 Category: Cardiology Authors: dr s venkatesan Tags: Basic sciecne Basic science -Physiology Best books in cardiology bio ethics great cardiologists best books in cardiac physiology best cardiology books cardiovascular physiology famous Seattle doctors Great Men in cardiology history of Source Type: blogs

Fight Aging! Newsletter, February 1st 2021
In this study, we characterize age-related phenotypes of human hematopoietic stem cells (HSCs). We report increased frequencies of HSC, hematopoetic progenitor cells (HPC), and lineage negative cells in the elderly but a decreased frequency of multi-lymphoid progenitors. Aged human HSCs further exhibited a delay in initiating division ex vivo though without changes in their division kinetics. The activity of the small RhoGTPase Cdc42 was elevated in aged human hematopoietic cells and we identified a positive correlation between Cdc42 activity and the frequency of HSCs upon aging. The frequency of human HSCs polar fo...
Source: Fight Aging! - January 31, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

An Interview with Ronjon Nag, Investor in the Longevity Industry
Ronjon Nag is an academic turned inventor turned entrepreneur turned investor in the communications and software industries, and now of late the longevity industry, a career path shared with a growing number of his peers in the Bay Area investment community. Alongside his principals Anastasiya Giarletta and Artem Trotsyuk, Ronjon Nag runs R42, a fund that grew out of his angel investing experience and successes. As is the case for near all of those who arrived comparatively early to the advent of this new industry, the R42 Group principals have a strong personal interest in health and longevity. The longevity indust...
Source: Fight Aging! - January 26, 2021 Category: Research Authors: Reason Tags: Investment Source Type: blogs

Wanted: NIGMS Program Directors for BBCB and PPBC
We’re recruiting two accomplished scientists for positions in our Division of Biophysics, Biomedical Technology, and Computational Biosciences (BBCB) and our Division of Pharmacology, Physiology, and Biological Chemistry (PPBC). The successful applicants will be responsible for scientific and administrative management of a portfolio of research grants, and will stimulate, plan, advise, direct, and evaluate program activities related to their field of expertise. The BBCB position is in our Bioinformatics and Computational Biology Branch, which supports bioinformatics and computational approaches that join biology ...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - January 14, 2021 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Job Announcements Source Type: blogs

Fight Aging! Newsletter, January 11th 2021
This study demonstrates the potential of a natural (o-Vanillin) and a synthetic (RG-7112) senolytic compounds to remove senescent IVD cells, decrease SASP factors release, reduce the inflammatory environment and enhance the IVD matrix production. Removal of senescent cells, using senolytics drugs, could lead to improved therapeutic interventions and ultimately decrease pain and a provide a better quality of life of patients living with intervertebral disc degeneration and low back pain. From Ying Ann Chiao of Oklahoma Medical Research Foundation: Mitochondrial dysfunction plays a central role in aging and cardiovasc...
Source: Fight Aging! - January 10, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Ageless: The New Science of Getting Older Without Getting Old
is a forthcoming book discussing the aging research community and its newfound interest in treating aging as a medical condition. Aging is the cause of age-related disease and mortality, and far longer, far healthier lives lie ahead in the era in which the mechanisms of aging are targeted, rather than only their consequences. In this popular press article, the author and the book are discussed. The views are sensible and forward-looking, suggesting that it may be worth picking up when it is published in a few months. The author began professional life as a physicist. As a child, he was fascinated by space, the wa...
Source: Fight Aging! - January 7, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Alice in Nutcaseland
People have always been subject to elaborate false belief systems, from believing the Oracle at Delphi to the resurrection of Jesus to the Protocols of the Elders of Zion. It ' s nothing new. All three of the above, have done a lot of harm, along with countless other hoaxes.* But are we in a particularly deranged period of history?  The big difference from the past, or at least we thought so up until recently, is that we had the Scientific Revolution and developed rules of evidence, along with the technological means to evaluate reality and the communicative infrastructure to converge on a consensus about what is...
Source: Stayin' Alive - January 5, 2021 Category: American Health Source Type: blogs

Fight Aging! Newsletter, December 21st 2020
In this study, we have found that administration of a specific Sgk1 inhibitor significantly reduces the dysregulated form of tau protein that is a pathological hallmark of AD, restores prefrontal cortical synaptic function, and mitigates memory deficits in an AD model. These results have identified Sgk1 as a potential key target for therapeutic intervention of AD, which may have specific and precise effects." Targeting histone K4 trimethylation for treatment of cognitive and synaptic deficits in mouse models of Alzheimer's disease Epigenetic aberration is implicated in aging and neurodegeneration. Using p...
Source: Fight Aging! - December 20, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Forthcoming Book: Replacing Aging
Replacing Aging is a forthcoming book on the treatment of aging as a medical condition. It is presented as putting forward a similar point of view to that found in Ending Aging by Aubrey de Grey and Michael Rae, meaning that the research and medical communities should place a relentless focus on damage and repair of damage. Aging is caused by an accumulation of molecular damage of a few distinct classes in and around cells, that damage spiraling out into a complex network of interacting downstream consequences. Fully understanding that network, fully understanding the progression of aging, will take the rest of this...
Source: Fight Aging! - December 14, 2020 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs

Microbubbles Deliver Drugs Directly to Tumors
When fighting cancerous tumors, all too often the very drugs that can destroy a lesion tend to have significant negative effects on the rest of the body. Doses have to be maintained at moderate levels to avoid side-effects that are even worse than the disease. In light of this, researchers have been trying to develop ways to more precisely deliver cancer drugs so that they target where they are needed. An exciting new approach, which involves using microbubbles to deliver drugs directly to tumors, has shown significant promise thanks to researchers at the University of Leeds in England. A team there has now shown that ...
Source: Medgadget - December 10, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Materials Medicine Nanomedicine Oncology Source Type: blogs