Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Progress Towards Therapies for Transthyretin Amyloidosis
Transthyretin is one of the few proteins in the body that can misfold in a way that encourages other copies of the protein to also misfold, forming solid aggregates called amyloid that disrupt tissue structure and function. The resulting condition, transthyretin amyloidosis, clogs up cardiac tissue and thereby contributes to a fraction of all heart failure cases. It is thought to be a major cause of mortality in supercentenarians. Approved therapies targeting a more aggressive form of the condition resulting from a mutated transthyretin gene will not be useful against the much more common version of the condition, as they ...
Source: Fight Aging! - August 18, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Top 6 Companies Using AI In Drug Discovery And Development
What if coming up with a new drug could be measured in days rather than years? What if new medication would cost thousands instead of billions of dollars? Just look at how an AI pharma start-up developed a potential new drug in 46 days! Artificial intelligence technologies promise to speed up the process of drug discovery and development and make it more cost-effective. As the market is flourishing, and it takes time and effort to separate the wheat from the chaff, we collected the most promising AI pharma companies out there.
Drug design is a key area AI is revolutionizing. In one of our latest database projects, we de...
Source: The Medical Futurist - August 17, 2023 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Pharma Genomics research clinical trials AI drug development medication drug discovery drug research cure Source Type: blogs
GenHealth.AI Accelerates into Healthcare AI Market with New Funding, Advisor Appointments and Use Cases Across Healthcare
AI Start-up Pioneering Generative AI for Healthcare Receives $13M in Early Funding, Adds Industry Luminaries as Advisors, and Kicks off Use Cases for Health Insurance Plans and Provider Systems
GenHealth.ai, a game-changing generative AI startup, is pushing the boundaries of AI in healthcare. The new company spun out of healthcare interoperability leader 1upHealth three months ago and secured $13M in funding, co-led by Craft Ventures and Obvious Ventures. GenHealth.ai also added industry leaders to its advisory board and launched numerous use cases for health insurance plans, pharmacies, and healthcare providers.
Most of t...
Source: EMR and HIPAA - August 10, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT 1upHealth Aneesh Chopra CareJourney Craft Ventures Don Rucker MD Eric Marriott Ethan Siegel GenHealth.ai Health IT Funding Health IT Fundings Health IT Investment Obvious Ventures Ricky Sahu Source Type: blogs
Podcast Episode Recommendation: Healthy Dose of Dialogue Episode 31 " A Dose of Prescription Drug Disruption "
Today, I am recommending a podcast episode worth listening to. Specifically, it is an episode from June 15, 2022 of the podcast known as " Healthy Dose of Dialogue " which describes its mission to " gather the brightest minds in healthcare to share their unique perspectives on transformative marketplace trends, industry insights, and their vision for the future " .This particular episode (EP31: " A Dose of Prescription Drug Disruption " ) is an interview with the President of CivicaScript LLC, which in case you weren ' t aware of it, is an affiliated business unit of the nonprofit drug company Civica, Inc. The president of...
Source: Scott's Web Log - August 9, 2023 Category: Endocrinology Tags: 2023 Biosimilar Civica Civica Rx CivicaRx CivicaScript insulin podcast podcast episode recommendations ypsomed Source Type: blogs
When Mark Cuban Cost Plus Drug Company Says Your Prescription is " Out of stock "
My followers may recall that about a year ago (on August 22, 2023), I blogged about (see https://blog.sstrumello.com/2022/08/generic-crestor-pricing-insanity.html for the post) that I had made a conscious decision to simply disintermediate my own insurance pharmacy benefit to buy an inexpensive generic statin drug because my own pharmacy benefit manager was screwing me. Currently, I ' m covered by Aetna which is now owned by CVS Health, which also owns the PBM known as Caremark. Caremark was robbing me on the statin. It was overcharging me. They were trying to charge me $33.85 for a 90-day supply of a cheap...
Source: Scott's Web Log - August 1, 2023 Category: Endocrinology Tags: 2023 cash pharmacy cash-only pharmacy Crestor Mark Cuban Cost Plus Drug Company rosuvastatin calcium Source Type: blogs
Enhancing Patient Adherence & Improving Treatment Outcomes
The following is a guest article by Christine Lee, Head of Health Partnerships at AnalyticsIQ
Patients seeking healthcare for their ailments often receive detailed treatment plans tailored to their individual needs. However, the efficacy of these treatment plans relies heavily on patient adherence. Unfortunately, research indicates that only about half of the patients adhere to their prescribed treatments consistently and correctly. This surprising statistic reveals a significant problem in our healthcare system, especially for those with chronic conditions requiring ongoing treatments.
But how can we collectively combat t...
Source: EMR and HIPAA - August 1, 2023 Category: Information Technology Authors: Guest Author Tags: Ambulatory Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System LTPAC AnalyticsIQ Christine Lee Chronic Conditions Healthcare Accesibility Healthcare Barriers Improving Outcomes P Source Type: blogs
An MBA in Regulatory Confusion
Welcome to the world of therapeutic use of tissues – an exciting and evolving arena of 21st century medicine and one of the many areas of medical products regulated by the FDA. And, as with many other areas of the agency’s jurisdiction, peculiar bureaucratic intervention and lack of clarity are causing harm to patients and costing American jobs. (Source: drugwonks.com Blog)
Source: drugwonks.com Blog - July 31, 2023 Category: Pharmaceuticals Source Type: blogs
Fight Aging! Newsletter, July 31st 2023
In conclusion, an SBP level below 130 mmHg was found to be associated with longevity among older women. The longer SBP was controlled at a level between 110 and 130 mmHg, the higher the survival probability to age 90. Preventing age-related rises in SBP and increasing the time with controlled BP levels constitute important measures for achieving longevity.
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Source: Fight Aging! - July 30, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Lobbying Efforts for the Development of Means to Treat Aging are at a Very Early Stage
That so many people turn their hand to lobbying government is a sad statement of the character of our era. Those engaged in getting things done start to feel, at some level of funding, that lobbying is a necessary defense on the one hand, against Big Pharma entities who will use regulators to impede and coerce competition, and on the other hand a way to access greater funding and publicity. The trough of public funds is ever an attractive proposition, and never as easy to access without tainting everything involved as people would like to think it is. A world with smaller, less powerful governments would be a world in whic...
Source: Fight Aging! - July 24, 2023 Category: Research Authors: Reason Tags: Politics and Legislation Source Type: blogs
Science: Sanity's Home Field Advantage
(Source: drugwonks.com Blog)
Source: drugwonks.com Blog - July 21, 2023 Category: Pharmaceuticals Source Type: blogs
Owning PBMs
(Source: drugwonks.com Blog)
Source: drugwonks.com Blog - July 21, 2023 Category: Pharmaceuticals Source Type: blogs
Attention Chairman Sanders, Nulla mensa sine impensa
(Source: drugwonks.com Blog)
Source: drugwonks.com Blog - July 20, 2023 Category: Pharmaceuticals Source Type: blogs
