Quickbite Interviews: 1UpHealth & Cecelia Health
I was at the VIVE conference in Miami last week and caught up with a number of CEOs & execs for some quickbite interviews — around 5 mins getting (I hope) to the gist of what they & their companies are up to. I am going to dribble them out this week. Up here are are Joe Gagnon, CEO, 1upHealth, a data integrator that works primarily with health plans, and Mark Clermont, CEO, Cecelia Health, a chronic care management company that also runs pharma patient adherence programs. — Matthew Holt (Source: The Health Care Blog)
Source: The Health Care Blog - March 16, 2022 Category: Consumer Health News Authors: matthew holt Tags: Health Tech Health Technology Matthew Holt 1UpHealth Cecilia Health Joe Gagnon Mark Clermont QuickBites ViVE2022 Source Type: blogs

Blame to go around on the opioid epidemic
The Purdue Pharma settlement gave family members of people who were harmed by opioid prescribingthe opportunity to confront Purdue family members, a dramatic spectacle that represents some measure of justice but casts blame for the disaster of the opioid epidemic on one family. That is not the whole story, or really a true story. Prior to the 1980s, opioids were generally prescribed in the U.S. only for short-term use, after surgery or severe injury, or for people who were terminally ill.In the 1980s, for reasons which are not entirely clear, attitudes in the medical profession began to shift and physicians began to t...
Source: Stayin' Alive - March 14, 2022 Category: American Health Source Type: blogs

Introducing ‘ The Digital Health Course ’ !
We are so happy and proud to finally share with you the biggest project The Medical Futurist has ever worked on: The Digital Health Course. We designed this course to provide a complete overview of digital health, guiding users through the technological aspects, and equipping them to be able to predict and forecast what’s coming next. From the basics and its definition to why it’s a cultural transformation that is happening now; how it is a paradigm shift of care; how you can spot trends in it and forecast the near future. The whole Medical Futurist team and I have put our hearts, brains and souls ...
Source: The Medical Futurist - March 8, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Digital Health Research E-Patients Future of Medicine Future of Pharma digital health course Future of healthcare Source Type: blogs

Canadian study finds causal link between time playing videogames at age 12 and ADHD symptoms at age 13
Recent studies have linked screen time — including video game play — to concerning outcomes in children, including low self-esteem, low life satisfaction, and depressive symptoms. Screen time has also been found to be correlated with symptoms of ADHD in children and adolescents, even when earlier attention difficulties are taken into account. These findings suggest that excessive video game play may be a risk factor for the development of ADHD symptoms. Other research suggests the possibility of reverse causation, i.e., that ADHD symptoms predicts the development of excessive video game play. Determining whether causal...
Source: SharpBrains - March 7, 2022 Category: Neuroscience Authors: Dr. David Rabiner Tags: Brain/ Mental Health Education & Lifelong Learning Technology & Innovation adhd ADHD-symptoms adolescence screen time screens video-games videogames Source Type: blogs

Generic Glucagon for $200, Where's the Savings? Get it for $5...WITH a coupon
In December 2020, the U.S. FDA approved several long-delayed generic versions of traditional mix-and-inject form of glucagon emergency kits. Among them were from Amphastar Pharmaceuticals, Inc. of Rancho Cucamonga, CA https://www.globenewswire.com/news-release/2020/12/29/2151177/0/en/Amphastar-Announces-Approval-for-Glucagon-for-Injection-Kit-1mg.html which was the very first, followed by another from Fresenius Kabi USA based in Lake Zurich, IL (in suburban Chicago, the parent company is based in Germany)https://www.businesswire.com/news/home/20200205005106/en/Fresenius-Kabi-Introduces-Glucagon-Emergency-Medicine-Kit....
Source: Scott's Web Log - March 7, 2022 Category: Endocrinology Tags: 2022 FDA generic glucagon Source Type: blogs

Fight Aging! Newsletter, February 28th 2022
In conclusion, as BMI and waist circumference are related to elevations of immune markers in the IL-6 pathway, chronic inflammation might be an important mediator of the relationship between BMI and frailty. Fat Tissue Becomes Dysfunctional with Age as Mitochondria Falter https://www.fightaging.org/archives/2022/02/fat-tissue-becomes-dysfunctional-with-age-as-mitochondria-falter/ Mitochondria are effectively power plants, hundreds of them working in every cell to produce chemical energy store molecules to power cellular processes. Mitochondrial function declines with age, unfortunately, for underlying r...
Source: Fight Aging! - February 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Against Testosterone Treatments for Older People
This cutting opinion piece is written in opposition to the prevalence of testosterone therapy, offered in many cases with the (dubious) promise of it being a way to push back the advance of aging. Hormone therapies in general are not to be taken lightly, but are widely used. Anyone should be free to try whatever they feel may work for them, but this approach may not be justified for most people given the balance of risk and benefit. That isn't a justification for restriction of personal freedom, but rather for greater efforts to educate in the face of overly enthusiastic marketing. It is not easy in the present en...
Source: Fight Aging! - February 22, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Everything You Need To Know About The Future Of Medicine
We describe the three cornerstones of privacy of every privacy discussion going forward: the traditional, the new and the future spheres that deal with your health data, and put forward recommendations on how you can start protecting yourself. More info At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today. If you’d like to support this mission, we invite you to join The Medical Futurist Patreon Community. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech d...
Source: The Medical Futurist - February 15, 2022 Category: Information Technology Authors: Judit Kuszkó Tags: TMF Artificial Intelligence in Medicine Digital Health Research E-Patients Future of Pharma Health Sensors & Trackers books tmfi The Guide To The Future Of Medicine Source Type: blogs

The torrent of bullshit
It ' s paywalled, but if you still have a NYT free read left you might want to check outGetting Rid of Joe Rogan Won ' t Solve the Health Misinformation Problem, by Julia Belluz and John Lavis. As they rightly point out, Joe Rogan and his guests spew dangerous falsehoods, but we ' re swimming in an ocean of crap.  Health disinformation is as old as commerce. In the 19th Century, all of medicine was basically bunk, but people made fortunes selling worthless " patent medicines, " through traveling shows or by mail order, and in stores. It wasn ' t until 1912 that congress passed legislation outlawing labels with fa...
Source: Stayin' Alive - February 8, 2022 Category: American Health Source Type: blogs

After the Crash
By JEFF GOLDSMITH These are grim days for innovative healthcare companies.  The health tech and care innovation firms mature enough to make it to public markets have been eviscerated in the ongoing market correction. As of January 29, 2022, high fliers like One Medical (down 83% from peak), Oscar (down 83%), Bright Healthcare (down 85%), Teladoc (down 77% but still selling at 6X revenues!), and AmWell (down 90%) are the tip of a much larger melting iceberg.    The dozens of digital health unicorns (e.g. pre-public companies valued at more than $1 billion) and their less mythical brethren, into which inves...
Source: The Health Care Blog - February 3, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech Health Technology Gartner Group health innovation Innovative Health Companie Jeff Goldsmith Source Type: blogs

What Is The Technological Future Of Medication Management?
When a patient heads to a healthcare institution and is prescribed medicines, one might expect them to stick to the regimen to improve their health. However, up to 50% of patients fail to adhere to their medications as prescribed.  And around the world, millions are taking medicines. In the U.K., over 26% of adults take prescription medications. Across the Atlantic ocean, in the U.S., some 66% of the adult population take prescription drugs. Down in the South Hemisphere, around 35% of Australians take such medicine on a daily basis.  With those millions of medicine-taking people comes the inevitable risk of...
Source: The Medical Futurist - February 3, 2022 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: E-Patients Future of Medicine Future of Pharma drugs telemedicine apps empowered patients digital pill smart pill NHS digital therapeutics Source Type: blogs

Otsuka and Virtual Reality start-up Jolly Good sign $43M deal to promote Social Skills Training (SST) therapies, helping schizophrenia patients first
Jolly Good and Teijin Pharma Form a Partnership to Develop VR Digital Therapeutics for Depression Otsuka signs on Jolly Good for $43M mental health VR deal (Fierce Biotech): The duo will build out software—hosted on Jolly Good’s VR goggles and connected tablet devices, and backed by Otsuka’s expertise in developing neurological therapeutics—that takes a social skills training (SST) approach to treating mental illness. SST is a behavioral therapy in which patients with anxiety, mood and personality disorders, among other conditions, are taught on a step-by-step basis how to navigate specific social interactions. The...
Source: SharpBrains - February 2, 2022 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Technology & Innovation behavioral-therapy Jolly Good mental illness neurological therapeutics Otsuka pharmaceutical schizophrenia social skills training Source Type: blogs

Digital therapeutics pioneer Akili Interactive plans to go public in mid-2022 at a $1B valuation
Palihapitiya-Led SPAC to Merge With Akili in $1 Billion Deal (Bloomberg): Akili Interactive, a startup that has developed a video game to help treat attention-deficit disorders in kids, has agreed to go public through a merger with one of Chamath Palihapitiya’s blank-check companies. The deal, which confirms a Bloomberg News report, values the combined entity at about $1 billion, Akili and Social Capital Suvretta Holdings Corp. I said in a statement seen by Bloomberg. It will provide as much as $412 million in gross cash proceeds, the companies said. Led by Chief Executive Officer Eddie Martucci, Akili has developed the ...
Source: SharpBrains - January 26, 2022 Category: Neuroscience Authors: SharpBrains Tags: Attention & ADD/ADHD Brain/ Mental Health Technology & Innovation Akili Interactive attention deficit hyperactivity disorder Chamath Palihapitiya cognitive-impairments digital therapeutics EndeavorRx FDA neuropsychiatric neuropsychia Source Type: blogs

Are ADHD medications overprescribed or underprescribed? (Quick answer: both)
Although medication treatment for ADHD has been shown to significantly reduce core ADHD symptoms in hundreds of studies, important concerns remain about it being prescribed inappropriately to children and teens who do not have ADHD. There is also evidence that many youth with ADHD who could potentially benefit from medication treatment do not receive it, and may realize poorer outcomes in as a result. Estimating the rate of the over- and under-use of ADHD medication is challenging, and a recent study provides the most comprehensive examination to date of this important issue: Assessing under-treatment and over-treatment of...
Source: SharpBrains - January 25, 2022 Category: Neuroscience Authors: Dr. David Rabiner Tags: Attention & ADD/ADHD Brain/ Mental Health Source Type: blogs

Fight Aging! Newsletter, January 24th 2022
In conclusion, senolytic drugs have shown promising results in the elimination of senescent cells and in alleviating various diseases in animal models. However, in patients, there is a paucity in data on the efficacy and safety of senotherapeutics from clinical trials, including systemic effects and side-effects. In this regard it is important to assess the specificity of senolytics in killing targeted senescent cells and their cytotoxic effects, to identify reliable markers for intervention responses, to elucidate interactions with comorbidities and other drugs, and to standardise administration protocols. FOXO3...
Source: Fight Aging! - January 23, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs