Solitary Isolated Oropharyngeal Neurofibroma Presenting With Dysphagia in the Setting of Von Recklinghausen's Disease
Ear Nose Throat J. 2024 Apr 18:1455613241249022. doi: 10.1177/01455613241249022. Online ahead of print.ABSTRACTA 24-year-old man with von Recklinghausen's disease presented with complaints of difficulty in swallowing for 6 months and change of voice for 3 months. He also had recent-onset difficulty in breathing. Telelaryngoscopy and subsequent contrast-enhanced computed tomography scan revealed a well-defined, smooth submucosal mass in the oropharynx (attached to the posterior pharyngeal wall, superior to the level of left aryepiglottic fold), obscuring the ipsilateral pyriform fossa, and nearly blocking the pharyngeal lum...
Source: Ear, Nose and Throat Journal - April 18, 2024 Category: ENT & OMF Authors: Shrita Sarkar Chandan Seth Mainak Dutta Saumendra Nath Bandyopadhyay Source Type: research
Interaction of selected alkoxy naringenin oximes with model and bacterial membranes
Biomed Pharmacother. 2024 Apr 16;174:116581. doi: 10.1016/j.biopha.2024.116581. Online ahead of print.ABSTRACTNaringenin is a flavonoid found in many fruits and herbs, most notably in grapefruits. In recent years, this compound and its derivatives have been of great interest due to their high biological activity, including fungicidal and bactericidal effects, also in relation to multidrug-resistant bacteria. Membrane interactions of naringenin oxime (NO) and its 7-O-alkyl (7-alkoxy) derivatives, such as methyl (7MENO), ethyl (7ETNO), isopropyl (7IPNO), n-butyl (7BUNO) and n-pentyl (7PENO) were studied. Thermotropic propert...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 18, 2024 Category: Drugs & Pharmacology Authors: Olga Weso łowska Anna Duda-Madej Maria B łaszczyk Kamila Środa-Pomianek Joanna Koz łowska Miros ław Anioł Source Type: research
Bench-to-bedside imaging in brain metastases: a road to precision oncology
This article offers insight into the molecular biology underlying brain metastasis, its pathogenesis, imaging protocols, and algorithms. It also discusses disease-specific molecular imaging features, focusing on common tumors that spread to the brain, such as lung, breast, colorectal cancer, melanoma, and renal cell carcinoma. Additionally, it covers various targeted treatment options, criteria for assessing treatment response, and the role of artificial intelligence in diagnosing, managing, and predicting prognosis for patients with brain metastases.PMID:38637186 | DOI:10.1016/j.crad.2024.02.015 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 18, 2024 Category: Cancer & Oncology Authors: S Shukla A Karbhari S Rastogi U Agarwal P Rai A Mahajan Source Type: research
Bench-to-bedside imaging in brain metastases: a road to precision oncology
This article offers insight into the molecular biology underlying brain metastasis, its pathogenesis, imaging protocols, and algorithms. It also discusses disease-specific molecular imaging features, focusing on common tumors that spread to the brain, such as lung, breast, colorectal cancer, melanoma, and renal cell carcinoma. Additionally, it covers various targeted treatment options, criteria for assessing treatment response, and the role of artificial intelligence in diagnosing, managing, and predicting prognosis for patients with brain metastases.PMID:38637186 | DOI:10.1016/j.crad.2024.02.015 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - April 18, 2024 Category: Cancer & Oncology Authors: S Shukla A Karbhari S Rastogi U Agarwal P Rai A Mahajan Source Type: research
Bench-to-bedside imaging in brain metastases: a road to precision oncology
This article offers insight into the molecular biology underlying brain metastasis, its pathogenesis, imaging protocols, and algorithms. It also discusses disease-specific molecular imaging features, focusing on common tumors that spread to the brain, such as lung, breast, colorectal cancer, melanoma, and renal cell carcinoma. Additionally, it covers various targeted treatment options, criteria for assessing treatment response, and the role of artificial intelligence in diagnosing, managing, and predicting prognosis for patients with brain metastases.PMID:38637186 | DOI:10.1016/j.crad.2024.02.015 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 18, 2024 Category: Cancer & Oncology Authors: S Shukla A Karbhari S Rastogi U Agarwal P Rai A Mahajan Source Type: research
Presynaptic density determined by SV2A PET is closely associated with postsynaptic metabotropic glutamate receptor 5 availability and independent of amyloid pathology in early cognitive impairment
CONCLUSIONS: Reductions in mGluR5 availability and synaptic density exhibit similar spatial patterns in AD and are closely linked.HIGHLIGHTS: Cognitively impaired patients exhibited lower mGluR5 availability and synaptic density in the medial temporal lobe than HCs. Reductions in mGluR5 availability and synaptic density exhibit similar spatial patterns in AD. Regional synaptic density was closely associated with regional mGluR5 availability. mGluR5 availability and synaptic loss partially mediated the relationship between amyloid deposition and global cognition. With further research, modulating mGluR5 availability might b...
Source: The Journal of Alzheimers Association - April 18, 2024 Category: Psychiatry Authors: Jie Wang Qi Huang Kun He Junpeng Li Tengfei Guo Yang Yang Zengping Lin Songye Li Greet Vanderlinden Yiyun Huang Koen Van Laere Yihui Guan Qihao Guo Ruiqing Ni Binying Li Fang Xie Source Type: research
Bench-to-bedside imaging in brain metastases: a road to precision oncology
This article offers insight into the molecular biology underlying brain metastasis, its pathogenesis, imaging protocols, and algorithms. It also discusses disease-specific molecular imaging features, focusing on common tumors that spread to the brain, such as lung, breast, colorectal cancer, melanoma, and renal cell carcinoma. Additionally, it covers various targeted treatment options, criteria for assessing treatment response, and the role of artificial intelligence in diagnosing, managing, and predicting prognosis for patients with brain metastases.PMID:38637186 | DOI:10.1016/j.crad.2024.02.015 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 18, 2024 Category: Cancer & Oncology Authors: S Shukla A Karbhari S Rastogi U Agarwal P Rai A Mahajan Source Type: research
Interaction of selected alkoxy naringenin oximes with model and bacterial membranes
Biomed Pharmacother. 2024 Apr 16;174:116581. doi: 10.1016/j.biopha.2024.116581. Online ahead of print.ABSTRACTNaringenin is a flavonoid found in many fruits and herbs, most notably in grapefruits. In recent years, this compound and its derivatives have been of great interest due to their high biological activity, including fungicidal and bactericidal effects, also in relation to multidrug-resistant bacteria. Membrane interactions of naringenin oxime (NO) and its 7-O-alkyl (7-alkoxy) derivatives, such as methyl (7MENO), ethyl (7ETNO), isopropyl (7IPNO), n-butyl (7BUNO) and n-pentyl (7PENO) were studied. Thermotropic propert...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 18, 2024 Category: Drugs & Pharmacology Authors: Olga Weso łowska Anna Duda-Madej Maria B łaszczyk Kamila Środa-Pomianek Joanna Koz łowska Miros ław Anioł Source Type: research
Bench-to-bedside imaging in brain metastases: a road to precision oncology
This article offers insight into the molecular biology underlying brain metastasis, its pathogenesis, imaging protocols, and algorithms. It also discusses disease-specific molecular imaging features, focusing on common tumors that spread to the brain, such as lung, breast, colorectal cancer, melanoma, and renal cell carcinoma. Additionally, it covers various targeted treatment options, criteria for assessing treatment response, and the role of artificial intelligence in diagnosing, managing, and predicting prognosis for patients with brain metastases.PMID:38637186 | DOI:10.1016/j.crad.2024.02.015 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - April 18, 2024 Category: Cancer & Oncology Authors: S Shukla A Karbhari S Rastogi U Agarwal P Rai A Mahajan Source Type: research
Bench-to-bedside imaging in brain metastases: a road to precision oncology
This article offers insight into the molecular biology underlying brain metastasis, its pathogenesis, imaging protocols, and algorithms. It also discusses disease-specific molecular imaging features, focusing on common tumors that spread to the brain, such as lung, breast, colorectal cancer, melanoma, and renal cell carcinoma. Additionally, it covers various targeted treatment options, criteria for assessing treatment response, and the role of artificial intelligence in diagnosing, managing, and predicting prognosis for patients with brain metastases.PMID:38637186 | DOI:10.1016/j.crad.2024.02.015 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 18, 2024 Category: Cancer & Oncology Authors: S Shukla A Karbhari S Rastogi U Agarwal P Rai A Mahajan Source Type: research
Performance of NiO doped on alkaline sludge from waste photovoltaic industries for catalytic dry reforming of methane
Environ Sci Pollut Res Int. 2024 Apr 18. doi: 10.1007/s11356-024-33325-7. Online ahead of print.ABSTRACTAlkali sludge (AS) is waste abundantly generated from solar photovoltaic (PV) solar cell industries. Since this potential basic material is still underutilized, a combination with NiO catalyst might greatly influence coke resentence, especially in high-temperature thermochemical reactions (Arora and Prasad, RSC Adv. 6:108,668-108688, 2016). This paper investigated alkaline sludge containing 3CaO-2SiO2 doped with well-known NiO to enhance the dry reforming of methane (DRM) reaction. The wet-impregnation method was used to...
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Mohd Razali Shamsuddin Siow Hwa Teo Tengku Sharifah Marliza Tengku Azmi Azizul Hakim Lahuri Yun Hin Taufiq-Yap Source Type: research
Body-Mounted MR-Conditional Robot for Minimally Invasive Liver Intervention
Ann Biomed Eng. 2024 Apr 18. doi: 10.1007/s10439-024-03503-2. Online ahead of print.ABSTRACTMR-guided microwave ablation (MWA) has proven effective in treating hepatocellular carcinoma (HCC) with small-sized tumors, but the state-of-the-art technique suffers from sub-optimal workflow due to the limited accuracy provided by the manual needle insertions. This paper presents a compact body-mounted MR-conditional robot that can operate in closed-bore MR scanners for accurate needle guidance. The robotic platform consists of two stacked Cartesian XY stages, each with two degrees of freedom, that facilitate needle insertion pose...
Source: Annals of Biomedical Engineering - April 18, 2024 Category: Biomedical Engineering Authors: Zhefeng Huang Anthony L Gunderman Samuel E Wilcox Saikat Sengupta Jay Shah Aiming Lu David Woodrum Yue Chen Source Type: research
Treatment of COVID-19-associated ARDS with umbilical cord-derived mesenchymal stromal cells in the STROMA-CoV-2 multicenter randomized double-blind trial: long-term safety, respiratory function, and quality of life
CONCLUSIONS: This study suggests a favorable safety profile for the use of intravenous UC-MSCs in the context of the first French wave of SARS-CoV-2-related moderate-to-severe acute respiratory distress syndrome, with no adverse effects observed at 1 year.PMID:38637891 | DOI:10.1186/s13287-024-03729-w (Source: Cell Research)
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Alexandre Sitbon Caroline Hauw-Berlemont Miryam Mebarki Nicholas Heming Julien Mayaux Jean-Luc Diehl Alexandre Demoule Djillali Annane Cl émence Marois Sophie Demeret Emmanuel Weiss Guillaume Voiriot Muriel Fartoukh Jean-Michel Constantin Bruno M égarba Source Type: research
Presynaptic density determined by SV2A PET is closely associated with postsynaptic metabotropic glutamate receptor 5 availability and independent of amyloid pathology in early cognitive impairment
CONCLUSIONS: Reductions in mGluR5 availability and synaptic density exhibit similar spatial patterns in AD and are closely linked.HIGHLIGHTS: Cognitively impaired patients exhibited lower mGluR5 availability and synaptic density in the medial temporal lobe than HCs. Reductions in mGluR5 availability and synaptic density exhibit similar spatial patterns in AD. Regional synaptic density was closely associated with regional mGluR5 availability. mGluR5 availability and synaptic loss partially mediated the relationship between amyloid deposition and global cognition. With further research, modulating mGluR5 availability might b...
Source: The Journal of Alzheimers Association - April 18, 2024 Category: Psychiatry Authors: Jie Wang Qi Huang Kun He Junpeng Li Tengfei Guo Yang Yang Zengping Lin Songye Li Greet Vanderlinden Yiyun Huang Koen Van Laere Yihui Guan Qihao Guo Ruiqing Ni Binying Li Fang Xie Source Type: research
Fungicidal efficiency of DBD cold plasma against Aspergillus niger on dried jujube
This study investigated the fungicidal efficiency and mechanism of action of dielectric barrier discharge cold atmosphere plasma (DBD-CAP) in inactivating Aspergillus niger (A. niger) spores. The disinfection efficacy and quality of dried jujube used as the processing application object were also studied. The results indicated that the Weibull + Tail model performed better for spore inactivation curves at different voltages among various treatment times, and the spore cells were reduced by 4.05 log (cfu/mL) in spores suspension at 70 kV after 15 min of treatment. This disinfection impact was further supported by scanning e...
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Qiaoyun Wei Yuan Yuan Jianhao Zhang Jin Wang Source Type: research
