Implementation of Lung Cancer Screening in the First Line Zone of ZORA (Flanders), Using a Low Dose CT-scan
Conditions: Lung Cancer, Nonsmall Cell; Lung Cancer; Smoking Cessation; Lung Cancer, Small Cell Interventions: Radiation: Low-dose CT scan; Behavioral: Smoking Cessation Sponsors: University Hospital, Antwerp; Universiteit Antwerpen; Belgian Cancer Registry Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials

Pre-Study of Wild Type Enterotoxigenic E. Coli (ETEC) Strain for Verification of a Planned Challenge Dose
Conditions: ETEC Diarrhea Interventions: Other: Enterotoxigenic E. coli (ETEC) strain Sponsors: Scandinavian Biopharma AB; Johns Hopkins Bloomberg School of Public Health Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials

Effect of Postoperative Prolonged sedation with Dexmedetomidine after successful reperfusion with Endovascular Thrombectomy on long-term prognosis in patients with acute ischemic stroke (PPDET): study protocol for a randomized controlled trial
DiscussionThis randomized clinical trial is expected to verify the hypothesis that postoperative prolonged sedation with DEX after successful reperfusion may promote the long-term prognosis of patients with AIS and may reduce the related socio-economic burden.Trial registrationClinicalTrials.gov NCT04916197. Prospectively registered on 7 June 2021. (Source: Trials)
Source: Trials - March 4, 2024 Category: Research Source Type: clinical trials

Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial
Conditions: Castration-Resistant Prostate Carcinoma; Stage IVB Prostate Cancer AJCC v8 Interventions: Procedure: Biospecimen Collection; Procedure: Computed Tomography; Other: Gallium Ga 68 Gozetotide; Drug: Lutetium Lu 177 Vipivotide Tetraxetan; Procedure: Positron Emission Tomography; Other: Questionnaire Administration; Procedure: Single Photon Emission Computed Tomography Sponsors: Jonsson Comprehensive Cancer Center; Novartis Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer
Conditions: Extensive Stage Lung Small Cell Carcinoma; Stage IV Lung Cancer AJCC v8 Interventions: Biological: Atezolizumab; Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Biological: Durvalumab; Procedure: Echocardiography; Drug: Iadademstat; Procedure: Magnetic Resonance Imaging; Procedure: Multigated Acquisition Scan Sponsors: National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome
Conditions: Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome Interventions: Biological: Actinium Ac 225-DOTA-Daratumumab; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Procedure: Computed Tomography; Biological: Daratumumab; Procedure: Echocardiography; Drug: Fludarabine; Procedure: Hematopoietic Cell Transplantation; Biological: Indium In 111-DOTA-Daratumumab; Drug: Melphalan; Procedure: Multigated Acquisition Scan; Procedure: Radionuclide Imaging; Procedure: Single Photon Emission Computed Tomography; Drug: Sirolimus; Drug: Tacrolimus; R...
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials

Gestional Trophoblastic Neoplasia Ultrasound Assessment: Titanium Study
Conditions: Describe Typical Gray Scale/Color Doppler Ultrasound Features of Gestational Trophoblastic Neoplasia at the US Examination; To Assess if There Are Differences at the Baseline US Scan Between Low-risk and High-risk Patients; To Identify Ultrasound Predictors of Resistance to First-line Single Drug Chemotherapy in Low-risk GTN Patients; To Investigate if Machine Learning (ML) Algorithms (Radiomics, Deep Neural Networks (DNN), and Other Machine Learning Algorithms Sponsors: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials

Trueness of Full Arch Scans and Generated Digital Implant Models
Conditions: Denture, Complete Interventions: Device: conventional impression stone casts digitization; Device: digital scanning with coupled scanning aiding device; Device: Digital Implant Model assessment of accuracy Sponsors: Ain Shams University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Effects of Music Therapy on Psychological States Among Cancer Patients Undergoing MRI Scans and A Relevant Mediator
Conditions: Psycho-Oncology Interventions: Other: Music therapy Sponsors: Guangzhou Concord Cancer Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Echography Study_Anthropometric Measurements
Conditions: Healthy Subjects Interventions: Other: Ultrasound scans Sponsors: Crossject Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Imperial Prostate 9 - ATLAS (Approaches To Long-Term Active Surveillance)
Conditions: Prostate Cancer Interventions: Diagnostic Test: MRI Scans Sponsors: Imperial College Healthcare NHS Trust; East London NHS Foundation Trust; King ' s College; University College, London; University of York; University College London Hospitals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Investigating the Muscarinic System in Schizophrenia Using Positron Emission Tomography
Conditions: Schizophrenia; Schizophreniform Disorders Interventions: Radiation: PET Scan Sponsors: Centre for Addiction and Mental Health Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

The Effectiveness of iTero Element 5D NIRI System in Early Proximal Caries Detection in Permanent Teeth
Conditions: Dental Caries Interventions: Diagnostic Test: intraoral scanning; Diagnostic Test: clinical oral examination; Diagnostic Test: cone-beam computed tomography Sponsors: West China Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

Evaluation of Diagnoses and Clinical Outcomes in Children Undergoing MRI Scans
Conditions: Magnetic Resonance Imaging Sponsors: Jessa Hospital Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

D-OCT for Detection and Subtyping of BCC: a Diagnostic Cohort Study
Conditions: Basal Cell Carcinoma; Optical Coherence Tomography Interventions: Device: Vivosight Multi-beam Swept-Source Frequency Domain OCT scanner Sponsors: Maastricht University Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 22, 2024 Category: Research Source Type: clinical trials