DNA Damage and Consequent Inflammation in Heart Failure
One of the ways in which cell damage characteristic of aging can provoke inflammation is via the mislocalization of DNA. Either nuclear DNA or mitochondrial DNA can find its way to the cytosol, where it can trigger responses evolved to detect bacterial or viral infection, or severe cell damage. This creates a cascade of downstream signaling leading to an inflammatory response. In youth these events occur comparatively rarely, and in circumstances wherein immune response and potentially even cell death are beneficial. With age, however, there is a continued mild but growing level of dysfunction and consequent sustained infl...
Source: Fight Aging! - September 8, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Reducing Cardiovascular Risk Factor Also Reduces Incidence of Neurodegenerative Disease
It is well known that the aging of the vasculature contributes to the aging of the brain. The brain requires a great deal of energy to operate, and the nutrients and oxygen needed for optimal brain metabolism are supplied in the bloodstream. With age, capillary density declines, the heart becomes weaker, and blood vessels are narrowed by the development of atherosclerotic lesions. All of this combines to reduce the delivery of nutrients to the brain, and its metabolism suffers as a result. Here, researchers present additional evidence to support this view of the impact of cardiovascular aging on brain aging. Cardi...
Source: Fight Aging! - September 7, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Healthcare IT is Changing, Fast
The following is a guest article by Tim Bowe, CEO at Full Spectrum Throughout the past few decades, we have seen cycles within the healthcare information systems space related to the pressure associated with changing technologies, but that pressure is now greater than ever before.  There is currently an explosion of technology and regulatory changes that are just beginning to impact the industry. The educational topics at this year’s HIMSS conference shed light on some of those new pressures: AI and ML, Digital Health Transformation, Cybersecurity, and Data Science in Healthcare Information, just to name a few. Of cours...
Source: EMR and HIPAA - September 5, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Health IT Company Healthcare IT IT Infrastructure and Dev Ops Security and Privacy AI Engines cloud solutions Cybersecurity FDA FDA Security Full Spectrum Healthcare Cybersecurity Medical Devices Tim Bowe Ze Source Type: blogs

Time for a universal “exercise prescription” for kids and adults to boost cognition and mental health?
Welcome to a new edition of SharpBrains e‑newsletter, featuring this time a range of brain research findings, tools and controversies plus some brain teasers to challenge your (and our) working memory. #1. Major evidence review supports an “exercise prescription” for most adults to boost mental health “Higher intensity physical activity was associated with greater improvements” and “Effectiveness of physical activity interventions diminished with longer duration interventions.” The sweet spot was four or five half-hour effortful sessions per week. Are you hitting it? #2. (Separate) Evidence review: Ph...
Source: SharpBrains - August 31, 2023 Category: Neuroscience Authors: SharpBrains Tags: Attention & ADD/ADHD Brain Teasers Brain/ Mental Health Education & Lifelong Learning Peak Performance SharpBrains Monthly eNewsletter Technology & Innovation AirPods Apple boost mental health brain teasers for adults brain-activity Source Type: blogs

Strengthening Email Cybersecurity for Health Practices: Safeguarding Sensitive Patient Data
Conclusion With the increasing cybersecurity threats faced by health practices, prioritizing email security is paramount. Advanced email security solutions provide a comprehensive approach to protecting sensitive patient data, mitigating vulnerabilities, and ensuring regulatory compliance. By leveraging features such as robust filtering, anti-phishing measures, data loss prevention, encryption, and user education, healthcare organizations can enhance their email security posture and safeguard patient information effectively. (Source: EMR and HIPAA)
Source: EMR and HIPAA - August 29, 2023 Category: Information Technology Authors: Guest Author Tags: Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops LTPAC Security and Privacy Cybersecurity Data Breach Data Loss Prevention Email Cybersecurity Email Phishing Hea Source Type: blogs

Flurry of AI, Partnerships, and New Features Announced at Epic UGM
The theme of this year’s Epic User Group Meeting (UGM) was Castaway which was inspired by both the Tom Hank’s movie as well as earlier fare like Gilligan’s Island. A more appropriate theme may have been the Fast and Furious movies given the fast pace of announcements from senior company leaders on Day 2 of the event. Dressed in a brightly colored “island survivor“ outfit, Epic CEO Judy Faulkner strode onto the UGM stage to deliver her keynote address to the amassed audience of 38,000 customers and employees (virtual + in-person). Her hour-long speech was packed with updates. Generative AI Sprinkled through Faulkn...
Source: EMR and HIPAA - August 23, 2023 Category: Information Technology Authors: Colin Hung Tags: AI/Machine Learning C-Suite Leadership EMR-EHR Health IT Company Healthcare IT Hospital - Health System #EPICUGM Abridge Epic partnership program Epic Systems Generative AI InterSystems Judy Faulkner Microsoft Nuance PressGan Source Type: blogs

Ultrasound-Equipped Bra Monitors for Breast Cancer
Researchers at MIT have developed a wearable ultrasound system that is intended to allow women at high risk of breast cancer to perform an ultrasound scan on themselves at home, and may also let patients with early-stage malignancy or suspicious lesions to monitor how they are progressing. The technology can help patients to avoid having to attend a clinic, and may also help them to identify tumors that arise between routine breast checks at a clinic. The system consists of a piezoelectric ultrasound scanning module that fits into a rig that can be affixed to a bra. The rig includes openings into which the ultrasoun...
Source: Medgadget - August 22, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Cardiology Diagnostics Radiology Source Type: blogs

RFID in Healthcare: Navigating Security & Privacy Regulations
The following is a guest article by Peter Bloch, Market Development Manager – Healthcare at Avery Dennison Radio Frequency Identification (RFID) technology is revolutionizing healthcare, by improving efficiency, patient safety, and supply chain management. RFID technology involves using tags and readers to wirelessly identify and track objects. It has various applications in healthcare, including tracking medical equipment and medicines, monitoring patient movements, and managing medication inventory. Its ability to provide real-time information and automate processes has increased its adoption in the healthcare indu...
Source: EMR and HIPAA - August 21, 2023 Category: Information Technology Authors: Guest Author Tags: Healthcare IT Security and Privacy Avery Dennison Data Accuracy Drug Supply Chain Security Act DSCSA ePHI HIPAA Patient Privacy Peter Bloch Radio Frequency Identification RFID Source Type: blogs

Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Deep Learning for Medical Imaging: Use Cases and Network Types
Conclusion Medical image analysis solutions powered by deep learning technologies can reduce the risk of diagnostic errors and ensure timely interventions. But how to implement such a tool successfully? The key to successful deployment is cooperation with an experienced machine-learning solutions provider. Professional technical experts will help you choose an optimal architecture for your clinic’s specific goals and ensure effective model training. About Mariia Kovalova Mariia Kovalova is a Healthcare Technology Researcher at Itransition, a custom software development company headquartered in Denver, CO. Having work...
Source: EMR and HIPAA - August 18, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Health IT Company Healthcare IT CNN Convolutional Neural Networks Deep Learning GAN Generative Adversarial Networks Healthcare AI Healthcare Neural Networks Itransition MADGAN Mariia Kovalova Medical Imaging Source Type: blogs

Progress Towards Therapies for Transthyretin Amyloidosis
Transthyretin is one of the few proteins in the body that can misfold in a way that encourages other copies of the protein to also misfold, forming solid aggregates called amyloid that disrupt tissue structure and function. The resulting condition, transthyretin amyloidosis, clogs up cardiac tissue and thereby contributes to a fraction of all heart failure cases. It is thought to be a major cause of mortality in supercentenarians. Approved therapies targeting a more aggressive form of the condition resulting from a mutated transthyretin gene will not be useful against the much more common version of the condition, as they ...
Source: Fight Aging! - August 18, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Hopes and Questions raised by Alzheimer ’s drug Leqembi (lecanemab)
The FDA has approved Leqembi, the first disease-modifying treatment for early-stage Alzheimer’s and a precursor condition, mild cognitive impairment. Medicare has said it will pay for the therapy. Medical centers across the country are scrambling to finalize policies and procedures for providing the medication to patients, possibly by summer’s end or early autumn. It’s a fraught moment, with hope running high for families and other promising therapies such as donanemab on the horizon. Still, medical providers are cautious. “This is an important first step in developing treatments for complex neurodegenerative disea...
Source: SharpBrains - August 17, 2023 Category: Neuroscience Authors: Judith Graham at Kaiser Health News Tags: Brain/ Mental Health cognition early-stage Alzheimer’s Eisai FDA lecanemab Leqembi Medicare mild-cognitive-impairment Source Type: blogs

Proprio Raises $43M Series B Funding to Fuel Commercialization
First Light Field-Enabled Surgical Technology Company Secures Additional Institutional Capital to Drive Adoption of its AI-Driven Platform Proprio, a Seattle-based surgical technology company, today announced that it has secured $43 million in Series B funding from new and existing investors. The capital fuels commercialization to address significant demand for Proprio’s AI-driven surgical navigation platform in the US and overseas. Proprio’s flagship surgical navigation platform, Paradigm™, achieved a significant milestone this year by obtaining 510(k) clearance from the U.S. Food and Drug Administration (FDA). ...
Source: EMR and HIPAA - August 17, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Alf Grunwald Bird B. AG FDA Gabriel Jones Health IT Funding Health IT Fundings Health IT Investment PARADIGM Proprio Source Type: blogs