Answer to Case 684
Answer to theParasite Case of the Week 684: Anisakid L3 larvaeThe following is our third and final discussion from our amazing guest author and 3rd year medical student, Hadel Go. I ' m sure you will all agree that her discussions have been among the best we ' ve ever had on this blog. Congratulations on the excellent work, Hadel!_____________________ Worm cases are always my favorite because the comments are either “They are so beautiful!!” (@Parasite_Power on Twitter) or “…That’s a wholelottanope” (Valmik in the comments).This is a nematode in the Anisakidae family, likelyPseudoterranovaorAnisakis spp., ...
Source: Creepy Dreadful Wonderful Parasites - May 30, 2022 Category: Parasitology Source Type: blogs

Fight Aging! Newsletter, May 2nd 2022
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - May 1, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

ASC Specks as a Sizable Contribution to Chronic Inflammation
In this study, we tested the therapeutic potential of VHHASC and a newly generated VHH against murine ASC (VHHmASC) to target ASC specks in vitro and in vivo. We show that pre-incubation of extracellular ASC specks with VHHASC abrogated their inflammatory functions in vitro. Recombinant VHHASC rapidly disassembled pre-formed ASC specks and thus inhibited their ability to seed the nucleation of soluble ASC. Notably, VHHASC required prior cytosolic access to prevent inflammasome activation within cells, but it was effective against extracellular ASC specks released following caspase-1-dependent loss of membrane integrity, an...
Source: Fight Aging! - April 26, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Paracentesis: The Procedure
Discussion: The Z-track method minimizes fluid leakage from the puncture site. Injecting medication into the skin using this method is important to preventing post-procedure leaking. Once a needle has entered subcutaneous tissue and muscle, it opens a track that may not reseal immediately. There are also studies suggesting that Z tracks may reduce pain during injection. We suggest using the method during your paracentesis procedure.Z tracks are used for all kinds of intramuscular injections and can be applied to other sites on the body. Pull and press the skin and tissue 2 cm caudad to the deep abdominal wall and inser...
Source: The Procedural Pause - March 3, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Using Ultrasound for Paracentesis
​Paracentesis can be a quick and simple procedure with the right equipment and a well-rehearsed approach. It's important to practice this skill in the procedure lab and to familiarize yourself with the kit in your department a few times a year. This month, we focus on paracentesis set-up and basics, and next month we will review the nuts and bolts of completing the procedure.Important equipment for paracentesis: Five or six collection bottles, antiseptic prep, and a paracentesis kit. Consider longer needles for abdominal walls thicker than 2.5 cm.Grab the ultrasound and a pen. Position your patient at a 45-degree ang...
Source: The Procedural Pause - February 3, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Spontaneous bacterial peritonitis
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - February 13, 2019 Category: Internal Medicine Tags: gastroenterology hospital medicine Source Type: blogs

Abdominal Cocoon: DAMS Unplugged
Presenting a brief video on case of abdominal tuberculosis. Abdominal cocoon or sclerosing encapsulating peritonitis is a rare cause of intestinal obstruction. Thick  peritoneum encasing the small bowel is the main feature.  Famous Radiology Blog http://www.sumerdoc.blogspot.com TeleRad Providers at www.teleradproviders.com Mail us at sales@teleradproviders.com (Source: Sumer's Radiology Site)
Source: Sumer's Radiology Site - October 31, 2018 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Tropical Travel Trouble 009 Humongous HIV Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with a low ...
Source: Life in the Fast Lane - July 7, 2018 Category: Emergency Medicine Authors: Amanda McConnell Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs

What could be worse than being sued for malpractice? Prison.
Kang Se-hoon, a surgeon in South Korea, operated on a popular rock singer and song writer in October 2014. According to reports, Shin Hae-chul had abdominal pain, and the surgeon performed laparoscopic lysis of adhesions. Without having obtained consent, he decided to also do a weight reduction procedure. The patient was discharged a few days after surgery but returned a day later with fever and severe abdominal pain. Kang did not investigate the cause of the pain and instead prescribed pain medication. Shin Hae-chul was eventually transferred to another hospital where he underwent an attempt at life-saving surgery. Ten da...
Source: Kevin, M.D. - Medical Weblog - May 6, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/skeptical-scalpel" rel="tag" > Skeptical Scalpel, MD < /a > Tags: Physician Surgery Source Type: blogs

The cirrhosis chalk talk
Some days on ward rounds we have time for relatively short chalk talks.  Over the years I have developed many.  Learners seem to like this one in particular. We start with this question – name complications that cirrhotic patients develop for which we have secondary prevention.  Knowing this list and the associated drugs allows us to peruse the drug list to add to the PMH when it is not readily available. Here is my list: Esophageal varices – most patients with significant varices are taking a non-specific beta blocker.  More recently evidence suggests that carvedilol might be better than propranolol or nad...
Source: DB's Medical Rants - April 2, 2018 Category: Internal Medicine Authors: rcentor Tags: Medical Rants Source Type: blogs

Tropical Travel Trouble 005 RUQ Pain and Jaundice
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 005 Guest Post: Dr Branden Skarpiak – Global Health Fellow, Department of Emergency Medicine. UT Health San Antonio A 35 year old male presents to your emergency room for right upper quadrant pain that has gotten worse over the last 2-3 days. He also describes associated nausea, vomiting, and fevers. He denies other abdominal pain, or change in his bowel or bladder habits. His wife notes that he has started to “look more yellow” recent...
Source: Life in the Fast Lane - March 19, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine amebic amoeba amoebiasis amoebic dysentery amoebic liver abscess bloody diarrhoea e.dispar e.histolytica entamoeba histolytica Source Type: blogs

Funtabulously Frivolous Friday Five 210
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 210. Question 1 Burger King in Japan released the “Kuro Burger” in 2014, what ingredient did they use that could be found in an emergency department to make the burger black? + Reveal the Funtabulous Answer expand(document.getElementById('ddet968617044...
Source: Life in the Fast Lane - October 20, 2017 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five charcoal Curtis eye of the medicine man Fitz-Hugh fitz-hugh-curtis folie a deux rigler's triad Source Type: blogs

Winning the Doctor Lottery
By ANISH KOKA, MD A poignant piece recently appeared in the journal Health Affairs and was rapidly devoured on social media by the health policy community. The story is a harrowing first person account of a woman’s multiple interactions with doctors. The doctors in the story are either very good or very bad. One pediatrician turns the author and her sick son away on three consecutive days with colic, only to have a more careful partner sound the alarm and discover pyloric stenosis. The author then recounts the tale of her father’s death at age 42 due to a surgeon who operated for diverticulitis unnecessarily. ...
Source: The Health Care Blog - May 30, 2017 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs

Mandate
A few weeks ago I was awakened by a 2 a.m. call from the ED regarding a case of pneumoperitoneum. I barely recall the specifics of the conversation, but I vaguely remember snippets of phrases, words that light the fires and compel immediate action: "free air, tender all over, hypotension". I donned some old scrubs and quickly drove in to the hospital.The patient wasn't much older than me. He looked healthy, had a robust build. No other medical problems. But his vitals were perilously unstable. Heart rate 120's. Blood pressure 70 systolic despite several liters of fluid. The CT showed...
Source: Buckeye Surgeon - May 21, 2017 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs

MKSAP: 68-year-old man with new-onset ascites
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 68-year-old man is evaluated for new-onset ascites with lower-extremity edema. Symptoms have increased gradually over the past 4 weeks. He has consumed three alcoholic beverages per day for many years. His medical history is notable for coronary artery bypass graft surgery 8 months ago and dyslipidemia. His medications are low-dose aspirin, atorvastatin, and metoprolol. On physical examination, temperature is 36.8 °C (98.2 °F), blood pressure is 122/84 mm Hg, pulse rate is 64/min, and respiration rate is 16/...
Source: Kevin, M.D. - Medical Weblog - April 22, 2017 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions GI Source Type: blogs