Early diagnosis of tuberculous peritonitis in peritoneal dialysis patients using the T-SPOT test
AbstractA 49-year-old man was admitted with peritonitis nine months after starting continuous ambulatory peritoneal dialysis (CAPD) for kidney failure. Ceftazidime and cefazolin were started. Peritoneal dialysate culture was negative for bacteria, but antibiotic treatment was continued because peritonitis improved. Twenty days later, the patient was discharged with no signs of peritonitis. However, 40-day culture of the original peritoneal dialysate detectedMycobacterium tuberculosis, and peritonitis recurred, leading to readmission. A T-SPOT test was performed and was positive in 4  days. Anti-tuberculosis therapy was st...
Source: CEN Case Reports - April 21, 2024 Category: Urology & Nephrology Source Type: research

Circulating galectin-3 level association with cardiovascular risk factors during peritoneal dialysis
ConclusionsGal-3 was strongly associated with BNP, GDF-15, IVST and LVMI in patients undergoing PD treatment. Prospective studies should be carried out to determine whether Gal-3 can be a promising biomarker in predicting increased risk of adverse cardiovascular events in PD patients. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 20, 2024 Category: Urology & Nephrology Source Type: research

Health-related quality of life in paediatric patients on peritoneal dialysis: Data from a tertiary centre
Perit Dial Int. 2024 Apr 17:8968608241241177. doi: 10.1177/08968608241241177. Online ahead of print.ABSTRACTKidney failure has a negative impact on both children and families' quality of life (QOL). We evaluated the burden of home peritoneal dialysis (PD) using two local questionnaires and the French version of PedsQL3.0 end-stage kidney disease module and family impact module. Data are expressed as median (min-max). We reviewed the charts of 12 patients, at a median age of 8.8 (1.2-16.7) years, undergoing maintenance PD for 8 (1-42) months. Parathyroid hormone and haemoglobin levels were 215 (17-606) ng/L and 117 (104-141...
Source: Peritoneal Dialysis International - April 18, 2024 Category: Urology & Nephrology Authors: Elias Hajj Marijke Awouters Melodie Mosca Sacha Flammier Sarra Rachedi Justine Bacchetta Aurelie De Mul Bruno Ranchin Source Type: research

Is social deprivation associated with the peritoneal dialysis outcomes? A cohort study with REIN registry data
CONCLUSION: In PD patients, social deprivation was not associated with death or the composite event of death or transfer to HD. Socially deprived individuals had a greater risk of transfer to HD and lower access to kidney transplantation in the competing risk analysis.PMID:38632672 | DOI:10.1177/08968608241237685 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - April 18, 2024 Category: Urology & Nephrology Authors: Steve Biko Tobada Val érie Chatelet Clemence Bechade Antoine Lanot Annabel Boyer C écile Couchoud Fatouma Toure Sabrina Boime Thierry Lobbedez Mathilde Beaumier Source Type: research

Uremic toxins and the brain in chronic kidney disease
J Nephrol. 2024 Apr 16. doi: 10.1007/s40620-024-01929-4. Online ahead of print.ABSTRACTChronic kidney disease (CKD) patients have an increased risk for cognitive impairment compared to the general population. The risk is much higher in CKD patients who progress to end-stage kidney disease (ESKD) and require hemodialysis or peritoneal dialysis. Multiple factors may contribute to cognitive impairment in CKD patients and in patients on chronic dialysis. However, the observation that, after kidney transplantation, there is an improvement in several cognitive performance markers and that some structural and functional brain abn...
Source: Journal of Nephrology - April 16, 2024 Category: Urology & Nephrology Authors: Maurizio Bossola Barbara Picconi Source Type: research

Uremic toxins and the brain in chronic kidney disease
J Nephrol. 2024 Apr 16. doi: 10.1007/s40620-024-01929-4. Online ahead of print.ABSTRACTChronic kidney disease (CKD) patients have an increased risk for cognitive impairment compared to the general population. The risk is much higher in CKD patients who progress to end-stage kidney disease (ESKD) and require hemodialysis or peritoneal dialysis. Multiple factors may contribute to cognitive impairment in CKD patients and in patients on chronic dialysis. However, the observation that, after kidney transplantation, there is an improvement in several cognitive performance markers and that some structural and functional brain abn...
Source: Journal of Nephrology - April 16, 2024 Category: Urology & Nephrology Authors: Maurizio Bossola Barbara Picconi Source Type: research

BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway
ConclusionThe present results demonstrate that BMSC-Exos showed an obvious protective effect on PD-related PF and suggest that BMSC-derived exosomal miR-27a-3p may exert its inhibitory effect on PF and EMT progression by targeting TP53. (Source: Journal of Huazhong University of Science and Technology -- Medical Sciences --)
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - April 16, 2024 Category: Research Source Type: research

Risk factors of different mortality periods in older patients with end-stage renal disease undergoing urgent-start peritoneal dialysis: a retrospective observational study
The first six months of therapy represents a high-risk period for peritoneal dialysis (PD) failure. The risk of death in the first six months is higher for older patients treated with urgent-start PD (USPD). H... (Source: BMC Geriatrics)
Source: BMC Geriatrics - April 15, 2024 Category: Geriatrics Authors: Shizheng Guo, Liming Yang, Xueyan Zhu, Xiaoxuan Zhang, Zhanshan Sun, Lingfei Meng, Yangwei Wang, Jian Li, Siyu Cheng, Xiaohua Zhuang and Wenpeng Cui Tags: Research Source Type: research

Non-valvular atrial fibrillation in patients on peritoneal dialysis, prevalence, treatment and professionals involved
The objective of our study was to know the prevalence, treatment and professionals involved in the management of atrial fibrillation in peritoneal dialysis patients. For this purpose, we performed a descriptive analysis through a survey sent to different peritoneal dialysis units in Spain. A total of 1,403 patients on peritoneal dialysis were included in the study, of whom 186 (13.2%) had non-valvular atrial fibrillation. In addition, the assessment of the scores of thromboembolic and bleeding risks for the indication of oral anticoagulation was mainly carried out by the cardiologist (60% of the units), as well as its pres...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - April 12, 2024 Category: Urology & Nephrology Authors: Elisa Perez-Bernat M ª Angeles Viñas Manel Vera Miguel Gonz ález-Rico Marco Montomoli Elena Astudillo-Cort és Juan Carlos Quevedo-Reina Isabel Garc ía-Méndez Adoraci ón Martinez-Losa Ines Rama-Arias Mar ía Maldonado-Martín M ª Antonia Munar Agus Source Type: research

Exploring kidney dialysis costs in the United States: a scoping review
CONCLUSIONS: These findings indicate that prevention of or delay in progression to ESRD could have considerable cost savings for Medicare and private payers, particularly in patients with high-risk conditions such as type 2 diabetes. More efficient use of resources is needed, including low-cost medication, to improve clinical outcomes and lower overall costs, especially in high-risk groups. Widening access to PD where it is safe and appropriate may help to reduce dialysis costs.PMID:38605648 | DOI:10.1080/13696998.2024.2342210 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 12, 2024 Category: Health Management Authors: Fiona Stewart Kristin Kistler Yuxian Du Rakesh R Singh Bonnie B Dean Sheldon X Kong Source Type: research

Non-valvular atrial fibrillation in patients on peritoneal dialysis, prevalence, treatment and professionals involved
The objective of our study was to know the prevalence, treatment and professionals involved in the management of atrial fibrillation in peritoneal dialysis patients. For this purpose, we performed a descriptive analysis through a survey sent to different peritoneal dialysis units in Spain. A total of 1,403 patients on peritoneal dialysis were included in the study, of whom 186 (13.2%) had non-valvular atrial fibrillation. In addition, the assessment of the scores of thromboembolic and bleeding risks for the indication of oral anticoagulation was mainly carried out by the cardiologist (60% of the units), as well as its pres...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - April 12, 2024 Category: Urology & Nephrology Authors: Elisa Perez-Bernat M ª Angeles Viñas Manel Vera Miguel Gonz ález-Rico Marco Montomoli Elena Astudillo-Cort és Juan Carlos Quevedo-Reina Isabel Garc ía-Méndez Adoraci ón Martinez-Losa Ines Rama-Arias Mar ía Maldonado-Martín M ª Antonia Munar Agus Source Type: research

Exploring kidney dialysis costs in the United States: a scoping review
CONCLUSIONS: These findings indicate that prevention of or delay in progression to ESRD could have considerable cost savings for Medicare and private payers, particularly in patients with high-risk conditions such as type 2 diabetes. More efficient use of resources is needed, including low-cost medication, to improve clinical outcomes and lower overall costs, especially in high-risk groups. Widening access to PD where it is safe and appropriate may help to reduce dialysis costs.PMID:38605648 | DOI:10.1080/13696998.2024.2342210 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 12, 2024 Category: Health Management Authors: Fiona Stewart Kristin Kistler Yuxian Du Rakesh R Singh Bonnie B Dean Sheldon X Kong Source Type: research

Analysis of factors affecting sleep in peritoneal dialysis patients
Asian J Surg. 2024 Apr 11:S1015-9584(24)00550-5. doi: 10.1016/j.asjsur.2024.03.121. Online ahead of print.NO ABSTRACTPMID:38609828 | DOI:10.1016/j.asjsur.2024.03.121 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 12, 2024 Category: Surgery Authors: Yan Wang Yong-Chun Wang Li Wang Na Tian Source Type: research

Exploring kidney dialysis costs in the United States: a scoping review
CONCLUSIONS: These findings indicate that prevention of or delay in progression to ESRD could have considerable cost savings for Medicare and private payers, particularly in patients with high-risk conditions such as type 2 diabetes. More efficient use of resources is needed, including low-cost medication, to improve clinical outcomes and lower overall costs, especially in high-risk groups. Widening access to PD where it is safe and appropriate may help to reduce dialysis costs.PMID:38605648 | DOI:10.1080/13696998.2024.2342210 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 12, 2024 Category: Health Management Authors: Fiona Stewart Kristin Kistler Yuxian Du Rakesh R Singh Bonnie B Dean Sheldon X Kong Source Type: research