What Causes Mediastinal Masses?
Discussion The mediastinum resides in the chest and is the space bounded by the thoracic inlet cephalically, diaphragm caudally, sternum anteriorly and transverse process of the spine posteriorly, and mediastinal pleura and lungs laterally. It is divided into various compartments: Superior mediastinum Bounded by the thoracic inlet cephalically and a horizontal plane passing from the manubriosternal joint to the junction of T4/T5 vertebrae horizontally. Structures include: esophagus, trachea, parts of great vessels and first branches, great veins and initial branches, thymus, vagus, phrenic and other nerves, thoracic duct...
Source: PediatricEducation.org - February 20, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Janssen Reports Positive Topline Phase 2 Results for Nipocalimab in Pregnant Individuals at High Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)
SPRING HOUSE, PENNSYLVANIA, February 6, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced positive topline results from the proof-of-concept Phase 2 open-label UNITY clinical trial for the treatment of pregnant adults at high risk for severe hemolytic disease of the fetus and newborn (HDFN). HDFN is a serious and rare condition which can cause life-threatening anemia in the fetus. It occurs when the blood types of a pregnant individual and their fetus are incompatible.1 The trial met the primary endpoint, with the majority of pregnant patients who received nipocalimab achieving a live b...
Source: Johnson and Johnson - February 8, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Chilling Donors Not as Good as Machine Perfusion for Kidney Transplant
(MedPage Today) -- Therapeutic hypothermia of donors didn't preserve kidney function as well as machine perfusion of the organ during cold storage, a randomized trial found. Compared with kidneys pumped with a non-oxygenated, cold dialysate after... (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - February 3, 2023 Category: Surgery Source Type: news

Machine Perfusion of Kidneys Protects Against Delayed Graft Function
THURSDAY, Feb. 2, 2023 -- For brain-dead organ donors, therapeutic hypothermia is inferior to machine perfusion of the kidneys for reducing delayed graft function after transplantation, according to a study published in the Feb. 2 issue of the New... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 2, 2023 Category: Pharmaceuticals Source Type: news

AI improves digital x-ray detection of lung nodules
A group in Korea has developed an artificial intelligence (AI) model that coul...Read more on AuntMinnie.comRelated Reading: Digital chest x-ray technique improves detection of lung lesions DECT offers lower radiation dose alternative to perfusion CT AI improves lung nodule detection in health screening AI software boosts diagnostic precision for lung nodules on CT AI improves chest x-ray interpretation in real-world study (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 31, 2023 Category: Radiology Source Type: news

DECT offers lower radiation dose alternative to perfusion CT
Dual-energy CT (DECT) performs comparably to perfusion CT for assessing angiogenesi...Read more on AuntMinnie.comRelated Reading: 5 ways dual-energy CT improves emergency room neuroimaging Dual-energy CT shows promise for gout workup Osteoporosis risk can be predicted on dual-energy CT (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 6, 2023 Category: Radiology Source Type: news

Numerical investigation of skin and subcutaneous tissue thermal injury during elevated heating - Oguntala G, Sobamowo G, Hu YF.
This paper presents the non-Fourier bioheat transfer prediction methodology of human skin to determine skin burn injury with non-ideal properties of tissue, metabolism and blood perfusion. The dual-phase lag bioheat transfer model with the inclusion of eva... (Source: SafetyLit)
Source: SafetyLit - December 19, 2022 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

SPECT findings on neuropsychiatric symptoms caused by nitrous oxide abuse - Wang L, Yin L, Wang Q, Wang R, Liu Z, Dong M, Duan X, Zheng Y, Hong W, Liu F, Tie C.
OBJECTIVE: The aim of the study was to investigate the clinical, neuropsychological, and regional cerebral blood flow (rCBF) perfusion changes in patients with neuropsychiatric symptoms caused by nitrous oxide (N(2)O) abuse. METHODS: A total of 16 ... (Source: SafetyLit)
Source: SafetyLit - December 7, 2022 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Shock in trauma - Leech C, Turner J.
Shock is a life-threatening condition of circulatory failure leading to inadequate organ perfusion and tissue oxygenation. In a trauma patient, shock may be due to hypovolemia, cardiogenic, obstructive or distributive causes individually or in combination.... (Source: SafetyLit)
Source: SafetyLit - November 30, 2022 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Apathy in depression: an arterial spin labeling perfusion MRI study - Batail JM, Corouge I, Comb ès B, Conan C, Guillery-Sollier M, Vérin M, Sauleau P, Le Jeune F, Gauvrit JY, Robert G, Barillot C, Ferre JC, Drapier D.
INTRODUCTION: Apathy, as defined as a deficit in goal-directed behaviors, is a critical clinical dimension in depression associated with chronic impairment. Little is known about its cerebral perfusion specificities in depression. To explore neurovascular ... (Source: SafetyLit)
Source: SafetyLit - November 30, 2022 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Predicting outcomes post coronary artery surgery: SPECT or angio?
SPECT myocardial perfusion imaging may be a better approach than coronary angiograph...Read more on AuntMinnie.comRelated Reading: Does Tc-99m SPECT damage DNA? Ultrasound helpful for interventional cardiology procedures AI analysis of SPECT MPI scans can predict future cardiac events Report charts 80% drop in cardiac SPECT during COVID-19 Heart disease treatment planning viable on CCTA, FFR-CT (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - November 14, 2022 Category: Radiology Source Type: news

AI Reduced False Positives in Myocardial Perfusion Imaging Study AI Reduced False Positives in Myocardial Perfusion Imaging Study
In high-risk patients, deep-learning software used with a cardiac-dedicated camera reduced false positives on myocardial perfusion imaging by nearly 20%.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 19, 2022 Category: Consumer Health News Tags: Radiology News Source Type: news

SPECT/CT AI model predicts major adverse cardiac events
A deep-learning model developed for SPECT myocardial perfusion imaging coul...Read more on AuntMinnie.comRelated Reading: SPECT tracers go head-to-head in prostate cancer patients SPECT/CT proves value over CT diagnosing renal cancer Tc-99m SPECT/CT imaging detects COVID-19 SPECT/CT augmented reality may help visualize metastatic melanoma AI can detect metastatic bone lesions on scintigraphy (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - October 12, 2022 Category: Radiology Source Type: news

Renin as a Marker of Tissue Perfusion, Septic Shock and Mortality in Septic Patients: A Prospective Observational Study
Objectives: To characterize renin in critically ill patients. Renin is fundamental to circulatory homeostasis and could be a useful marker of tissue-perfusion. However, diurnal variation, continuous renal replacement therapy and drug-interference could confound its use in critical care practice. Design: Prospective observational study. Setting: Single-center, mixed medical-surgical ICU in Europe. Patients: Patients over 18 years old with a baseline estimated glomerular filtration rate greater than 30 mL/min/1.73 m and anticipated ICU stay greater than 24 hours. Informed consent was obtained from the patient or next-of-k...
Source: Current Awareness Service for Health (CASH) - September 9, 2022 Category: Consumer Health News Source Type: news

Perfusion Tests Comparable as Second-Line Diagnostic for Chest Pain
(MedPage Today) -- BARCELONA -- Cardiac magnetic resonance (CMR) and 82rubidium positron emission tomography (Rb-PET) performed equally well for perfusion imaging after coronary CT angiography, although with only modest sensitivity, the Dan-NICAD... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - August 29, 2022 Category: Cardiology Source Type: news