Children with severe traumatic brain injury, intracranial pressure, cerebral perfusion pressure, what does it mean? A review of the literature - Lovett ME, O'Brien NF, Leonard JR.
Severe traumatic brain injury is a leading cause of morbidity and mortality in children. In 2003 the Brain Trauma Foundation released guidelines that have since been updated (2010) and have helped standardize and improve care. One area of care that remains... (Source: SafetyLit)
Source: SafetyLit - February 18, 2019 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Head-Up CPR May Improve Neurologically Intact Survival Rates
Head-up CPR is a novel concept in resuscitation that has the potential to improve neurologically intact survival after cardiac arrest. Inspired by the clinical question of whether patients in cardiac arrest should be transported either head-up or feet-up in a small elevator, an initial animal study was performed in 2014. In this swine model of cardiac arrest, pigs underwent five-minute periods of automated CPR with an impedance threshold device (ITD-16) in the traditional supine position, then with a 30-degree whole-body head-up tilt, and then a 30-degree whole-body head-down tilt. The cerebral blood flow and cerebral perf...
Source: JEMS Patient Care - February 15, 2019 Category: Emergency Medicine Authors: Johanna C. Moore, MD, MS Tags: Cardiac & Resuscitation Top Story Exclusive Articles Patient Care Heart of America Source Type: news

EXTEND: More Evidence of tPA Benefit 9 Hours After Stroke EXTEND: More Evidence of tPA Benefit 9 Hours After Stroke
Past research showed MRI imaging can identify patients best suited for therapy; new results now show that CT perfusion imaging also works for patient selection.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 13, 2019 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Size and time impact outcomes when mechanical clot removal used for large core strokes
(American Heart Association) Patient outcomes with large core stroke damage are worse the larger the core volume and the longer the time lapse between stroke onset and treatment. Perfusion imaging may help identify large core stroke patients who are potential candidates for mechanical thrombectomy (clot removal). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 7, 2019 Category: International Medicine & Public Health Source Type: news

CT matches MRI for late-window stroke evaluation
Stroke patients who underwent endovascular therapy had similar improvement...Read more on AuntMinnie.comRelated Reading: Machine learning can predict stroke treatment outcomes Study reveals steep cost of delaying stroke treatment 3 CTA signs show which stroke patients can skip surgery Perfusion imaging expands window for stroke treatment CTA helps direct use of clot removal for stroke patients (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - February 6, 2019 Category: Radiology Source Type: news

Neovasc touts Reducer study
Neovasc (NSDQ:NVCN) this week touted a newly-published article that described the use of dipyridamole stress perfusion cardiac magnetic resonance to evaluate its Reducer device. The Vancouver-based company’s device is designed to treat refractory angina. The article, published in the Journal of the American College of Cardiology: Cardiovascular Interventions, featured a 66 year old man with angina who was treated with anti-ischemic therapy. Four months after being implanted with the Reducer, the patient was asymptomatic for angina and reported improved quality of life, according to Neovasc. A four-month dipyridamol...
Source: Mass Device - January 24, 2019 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Featured Vascular neovasc Source Type: news

RFPi wins FDA nod for non-contact blood flow imaging tech
RFPi’s iCertainty shows images of blood flow and perfusion without contact with the patient. FDA has cleared RFPi’s iCertainty real-time, noninvasive blood flow and perfusion imaging medical device for use during surgical procedures, the company said. iCertainty is the first medical imaging device to show blood flow without interrupting a surgical procedure or requiring injections, dyes, radiation or direct patient contact, according to the Greenville, N.C. company. Use of iCertainty during surgery could reduce procedural complications or repeat surgeries, reduce hospital costs, and objectively measure and help to...
Source: Mass Device - January 16, 2019 Category: Medical Devices Authors: Nancy Crotti Tags: Blog Blood Management Business/Financial News Food & Drug Administration (FDA) Imaging News Well Research & Development RFPi Source Type: news

Liver transplant 'game changing' treatment approved
It's hoped perfusion machines that "warm livers" will increase the number of viable donated organs. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - January 16, 2019 Category: Consumer Health News Source Type: news

Perfusion technique could boost number of viable donor livers
Slows rate of tissue deterioration and lengthens storage time, says NICE Related items fromOnMedica Primary sclerosing cholangitis New drive launched to trace hepatitis C patients Hepatocellular carcinoma risk, cirrhosis and hepatitis C Deaths from hepatitis C drop 11% in past year Alcohol consumption in late teens can predict risk of liver problems later (Source: OnMedica Latest News)
Source: OnMedica Latest News - January 16, 2019 Category: UK Health Source Type: news

IschemaView wins expanded FDA nod for Rapid neuroimager
Medical imaging dev IschemaView said today that it won expanded FDA clearance for its Rapid neuroimaging platform intended for use in selecting patients likely to benefit from endovascular thrombectomy. With the clearance, the Menlo Park, Calif.-based company said that its Rapid CT-Perfusion and Rapid MR-Perfusion devices can now be used to aid in selecting acute stroke patients with known occlusions of the internal carotid artery or proximal middle cerebral artery for a clot removal procedure. IschemaView touted its Rapid system as the only imaging platform approved for selecting stroke patients for clot removal. “T...
Source: Mass Device - January 15, 2019 Category: Medical Devices Authors: Fink Densford Tags: Food & Drug Administration (FDA) Imaging Neurological Regulatory/Compliance ischemaview Source Type: news

iSchemaView wins new FDA clearance for Rapid platform
Cerebrovascular imaging software developer iSchemaView has received an additional...Read more on AuntMinnie.comRelated Reading: iSchemaView reports rapid sales growth iSchemaView lands FDA nod for CTA software Perfusion imaging expands window for stroke treatment (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 15, 2019 Category: Radiology Source Type: news

Start-up BURL develops ultrasound-based 'ECG for stroke'
SAN FRANCISCO - A California start-up is developing an ultrasound-based device...Read more on AuntMinnie.comRelated Reading: Study reveals steep cost of delaying stroke treatment 3 CTA signs show which stroke patients can skip surgery 5 risk factors help predict brain hemorrhage on CT AI algorithm can triage head CT exams for urgent review Perfusion imaging expands window for stroke treatment (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 9, 2019 Category: Radiology Source Type: news

Temporal neurophysiological dynamics in traumatic brain injury - the role of pressure reactivity and optimal cerebral perfusion pressure for predicting outcome - Svedung Wettervik TM, Howells T, Enblad P, Lew én A.
Intracranial pressure (ICP), cerebral perfusion pressure (CPP) and the pressure reactivity index (PRx) have been shown to correlate with outcome after traumatic brain injury (TBI), but their temporal evolution is less studied. Optimal CPP (CPPopt), i.e. th... (Source: SafetyLit)
Source: SafetyLit - January 3, 2019 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Early Administration of Intravenous Fluids in Sepsis: Pros and Cons.
Fluid resuscitation in the management of patients with sepsis and severe sepsis has been considered the standard of care for almost 2 decades. The rationale for fluid resuscitation is related to improvement in cardiac output and organ perfusion. Recent research evidence challenges the use of fluid resuscitation in patients diagnosed with sepsis. Research is needed to determine the timing of fluid administration, as well as the volume and type of fluid to achieve positive patient outcomes. This journal article discusses the pros and cons of early fluid administration in the management of patients with sepsis. (Source: Curre...
Source: Current Awareness Service for Health (CASH) - December 28, 2018 Category: Consumer Health News Source Type: news

Fertility Tracker Guarantees Pregnancy Within One Year
Until recently, detecting the time during a woman’s cycle when she is most likely to conceive has been imprecise. Methods included measuring basal temperature spikes, which only detect ovulation after the fact, or urine tests that indicate a surge in luteinizing hormone, which predict ovulation is imminent within 12-36 hours. Both require meticulous recording of data by the user. Ava Science offers a fertility tracker that requires much less effort on the part of the user. Ava, a device that is worn on the wrist like a bracelet while the woman is sleeping, measures key physiological parameters to detect s...
Source: MDDI - December 14, 2018 Category: Medical Devices Authors: Susan Shepard Tags: Digital Health Source Type: news