Tribalism in pain rehabilitation
In this study, female patients and those without prior spine surgery appear to be most likely to benefit from fusion surgery for DDD.” The PCT is essentially a cast around the hips from waist to the top of the leg with a longer leg cast on the side that hurts. We can see similar appeals to single-factor causal models in studies of core stability – De Blaiser, Roosen, Willems, Danneels, Bossche, & De Ridder (2018) investigating whether this is a risk factor for lower extremity injuries in athletes, while Tayashiki, Mizuno, Kanehisa, & Miyamoto, (2018) investigated the causal effect of intra-abdominal...
Source: HealthSkills Weblog - November 25, 2018 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Clinical reasoning Pain conditions Professional topics Research Science in practice biopsychosocial clinical framework ideology Source Type: blogs

Atrophy of the Thymus Accelerates the Progression of Atherosclerosis
The thymus is where T cells mature, the training ground for the footsoldiers of the adaptive immune system. As the thymus declines in size and function with age, the supply of new T cells falls. This constrains and distorts the existing population of T cells, resulting eventually in chronic inflammation and immunosenescence, the failure the immune response and resulting vulnerability to pathogens and cancer. Atherosclerosis, meanwhile, is a condition of the innate immune system, in that it is caused by macrophages - a type of innate immune cell with origins that have nothing to do with the thymus - flocking to try and fail...
Source: Fight Aging! - November 23, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

FDA Clears Canon ’s Vantage Orian 1.5 Tesla MRI
Canon Medical won FDA clearance to bring to the U.S. market its brand new Vantage Orian 1.5 Tesla MRI scanner. It features a wide 71 centimeter bore and quiet operation thanks to its Pianissimo and Pianissimo Zen technologies. Pianissimo makes all scanning sequences quieter, while Pianissimo Zen allows certain scans to be performed at near ambient noise levels. To help young patients and those uncomfortable inside a scanner, Canon offers an immersive virtual experience called MR theater that combines audio and video to keep the person’s attention on something other than the scan. The scanner was developed to maximize...
Source: Medgadget - November 14, 2018 Category: Medical Devices Authors: Editors Tags: Emergency Medicine ENT Neurosurgery Radiology Source Type: blogs

Masimo ’s High Accuracy RD SET Pulse Oximeters Cleared by FDA
Masimo won FDA clearance for its RD SET sensors that feature the company’s “Measure-through Motion” and “Low Perfusion SET” pulse oximetry. The new disposable oximeters are supposedly twice as accurate than Masimo’s previous offerings for patients over 3 kg, having an accuracy spec of 1.5% at 1 standard deviation, compared to 3% before. The devices are purportedly also more comfortable for the patients to wear and easier to handle by clinicians. The cable is flat and lies along the patient’s finger, while having curved edges to prevent irritation. “We’re delighted to be...
Source: Medgadget - October 29, 2018 Category: Medical Devices Authors: Editors Tags: Anesthesiology Cardiac Surgery Cardiology Critical Care Emergency Medicine Pediatrics Source Type: blogs

Skeletonized internal mammary graft vs pedicled graft
Internal mammary artery (IMA) grafting is an important part of coronary artery bypass grafting. Arterial grafts give longer survival benefits compared to venous grafts. The conventional technique of IMA grafting uses pedicled grafts. Of late, skeletonized grafts are becoming more popular. The proposed advantage of skeletonized grafts is that when bilateral IMA grafts are used, there is less compromise on sternal vascularity and risk of deep sternal infections. Deep sternal infections are always a concern when using bilateral IMA grafts and can occasionally lead to sternal wound dehiscence. Pedicled graft is harvested en-b...
Source: Cardiophile MD - September 17, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiac Surgery Pedicled internal mammary graft Skeletonized internal mammary graft Skeletonized LIMA graft Source Type: blogs

A completely healthy 30-something woman with acute chest pain -- this post is loaded with info !!!
p.p1 {margin: 0.1px 0.0px 0.1px 0.2px; font: 11.0px Helvetica}A previously healthy young woman presented to the ED with one hour of acute onset right sided chest pain and pressure, very severe, radiating down the right arm.  Here is her initial ED ECG (time 0):What do you think?My impression:without any other information, I looked at this ECG and 2 features stood out: 1) the T-wave in lead I is hyperacute.  It is far too large for that QRS.  2) The T-wave in V6 is far too large; it is almost as tall as the R-wave, which is distinctly abnormal.  3) there is slight downsloping ST depression in V2 whi...
Source: Dr. Smith's ECG Blog - September 15, 2018 Category: Cardiology Authors: Steve Smith Source Type: blogs

Coronary artery and veins are married life long . . . with a purpose !
Cardiologist are always worried about the supply side of coronary blood flow. It’s fair enough, we can condone our brain for this one way thinking , afterall arterial supply remain the life-line for the heart. Some of us could (should) realise the importance of these  humble coronary veins which are anatomically and physiologically tied together.Its existence is as unique as their arterial counterpart.Coronary blood flow of about 250 ml traverses both the arms every minute.Imagine the scenario if the veins refuse to clear the blood from previous cardiac cycle . . . total hemodynamic chaos right ? Luckily such s...
Source: Dr.S.Venkatesan MD - September 9, 2018 Category: Cardiology Authors: dr s venkatesan Tags: cardaic physiology cardiology-Anatomy coronary sinus anatomy and physiology coronary sinus filling and emptying time drsvenkatesan coronary veno occlusive disorder coronary venous circulation acute coronary sinus syndrome coroanry vein cor Source Type: blogs

An Ischemic ECG and Bedside Echo shows diffuse dysfunction but with Apical Sparing
An approximately 40 y.o. male was in jail when he reported dyspnea.  He was brought to a small local ED where a chest x-ray showed pulmonary infiltrates.  He was hypotensive and hypoxic, and a provisional diagnosis of sepsis from pneumonia was made.  He had CT pulmonary angiogram which was read as " no PE. "  His lactate was 4.6 mEq/L and WBC count 20,000.  He was given levofloxacin, thentransferred to a tertiary care center.Upon arrival, his vitals were HR 115, BP 87/53, RR 30, T 37.3, and O2 sat 91% on room air. Breathing was labored, tachypneic.  He had cool extremities. ...
Source: Dr. Smith's ECG Blog - September 4, 2018 Category: Cardiology Authors: Steve Smith Source Type: blogs

Fight Aging! Newsletter, September 3rd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - September 2, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Tale of 2 Occlusions in the Same Patient: one with Expert ECG interpretation, the Other Without
Submitted by Nic Thompson, Written by Pendell Meyers, edits by Steve SmithThis is a long post, but well worth the read because it clearly delineates the difference in patient outcomes between advanced ECG interpretation and STEMI criteria!Dr. Thompson evaluated a male in his 40s with history of CAD s/p MI with PCI years ago, active smoking, HLD, HTN, who presented with chest discomfort and diaphoresis starting when the patient woke up a few hours prior to arrival. The pain waxed and waned until EMS arrived and gave him 325 mg aspirin en route, and had significant relief just prior to arrival. Here was his presentation...
Source: Dr. Smith's ECG Blog - September 2, 2018 Category: Cardiology Authors: Pendell Source Type: blogs

Cellular Senescence is One of the Causes of Age-Related Decline of Liver Regeneration
Tissue regeneration falters with age throughout the body, and there are numerous contributing factors to this decline. It is uncertain as to exactly how these factors layer in terms of cause and effect, however. One can point to the loss of stem cell activity, for example, and then ponder the degree to which that is secondary to rising levels of chronic inflammation. That chronic inflammation is in part inherent disarray and misconfiguration in the immune system stemming from exposure to persistent pathogens, but also arises from the accumulation of senescent cells that secrete strongly inflammatory signals. Now consider t...
Source: Fight Aging! - August 31, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

A False Appearance of Fine
​Like a million times before, the tech thrust an ECG in front of you. This one, however, grabbed every neuron's attention. Who was this?​The tech says the patient is a 70ish-year-old diabetic, hypertensive man brought to the emergency department because he has been feeling weak from a couple days of diarrhea.Where was he? Was he talking? What was his blood pressure?The tech pointed at one of the back rooms, and said, "Oh, his blood pressure is good—138/71, and he is talking to his family."He did look pretty good. His heart rate was 37 bpm as he chatted with his family. Staring back at the ECG, I think maybe...
Source: Lions and Tigers and Bears - August 31, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Fight Aging! Newsletter, July 30th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - July 29, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

New Evidence for Diminished Drainage of Cerebrospinal Fluid to be Important in Neurodegenerative Conditions
A number of research groups are building convincing evidence to show that reduced drainage of cerebrospinal fluid is an important contributing factor in the development of neurodegenerative diseases. A sizable fraction of these conditions are characterized by the aggregation of forms of altered or misfolded proteins, such as amyloid-β, tau, and α-synuclein. They precipitate to form solid deposits surrounded by a complex halo of biochemistry that harms and eventually kills brain cells. From what is known of amyloid-β, levels are quite dynamic, which all along has suggested that rising amounts in older brains are the resu...
Source: Fight Aging! - July 27, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Doctor . . , What about “ Pharmaco-Non Invasive ” approach for my husband ?
A young man aged around 40 years, had a STEMI was promptly thrombolysed in a small hospital located about 40 KM away in the suburbs of my city Chennai. They did an awesome job of saving the patient life and salvaging the myocardium. Now begins the story . . . one of the non-medical person who is the owner of the hospital has an unfortunate working  business relationship with a frighteningly big nearby hospital  which had signed a memorandum of irresponsible understanding . It demanded any  patient who arrives in the small hospital with MI should be transferred at earliest opportunity to them. So, an ambulance was arr...
Source: Dr.S.Venkatesan MD - July 21, 2018 Category: Cardiology Authors: dr s venkatesan Tags: Cardiology -Interventional -PCI Cardiology -Therapeutic dilemma Cardiology -unresolved questions Primary -PCI newer concepts in acute coronary syndrome pharmaco non invasive approach pharmaco-invasive approach rescue pci Source Type: blogs