An 80 year old man in VF arrest
An elderly man suffered out of hospital cardiac arrest. He was found in V Fib by EMS. He was shocked out of VF multiple times and arrived in VF arrest. We administered the fourth shock on arrival and obtained ROSC.His blood pressure was approximately 80/40, heart rate approximately 50 bpm.Here is his ECG at that time:What do you think? How does this affect your resuscitation?The ECG shows a junctional bradycardia with diffuse ST depression (maximal in leads V4-V6 and lead II), with large reciprocal STE in aVR. This is consistent with diffuse severe subendocardial ischemia, but without any clear evidence of acute occlusion....
Source: Dr. Smith's ECG Blog - March 25, 2019 Category: Cardiology Authors: Pendell Source Type: blogs

Brain abscess: Intracradiac Shunt
Case Report : 55 year old female presented with left sided focal seizures.  On examination, she had mild pyramidal weakness of left upper and lower limbs. Left plantar was extensor. There was cortical sensory loss on left upper and lower limbs. CVS examination  showed loud P2 and Ejection systolic murmur over the pulmonary area.  On MRI there is smooth ring enhancing lesion, which appeared bright on DW-MRI suggesting abscess. CXR and CT chest showed grossly dilated main pulmonary artery as well as branches. Echo showed ostium secundum ASD with  intracardiac shunt and moderately severe pulmonary art...
Source: Sumer's Radiology Site - March 20, 2019 Category: Radiology Authors: Sumer Sethi Source Type: blogs

ISCHEMIA Trial baseline data
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA) trial was sponsored by the New York University School of Medicine. Collaborators include National Heart, Lung, and Blood Institute (NHLBI), Stanford University, Duke University, Emory University, Harvard University and several other leading institutions. ISCHEMIA trial randomized 5179 patients with stable ischemic heart disease with moderate to severe degree of inducible ischemia on stress testing. Blinded CT coronary angiogram was used to exclude those with significant unprotected left main coronary artery disease or ...
Source: Cardiophile MD - March 16, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology Source Type: blogs

ARTIS icono Biplane Angiography System Unveiled by Siemens Healthineers
Siemens Healthineers has unveiled its ARTIS icono biplane angiography system at the 2019 European Congress of Radiology in Vienna, Austria. The system is particularly suited for neuroradiology procedures, such as removing stroke-causing blood clots, thanks to improved 2D and 3D imaging that can also lower the amount of radiation delivered to the patient. Moreover, quick switching between the 2D and volumetric modes can help to track procedural progression with greater ease. Because the imaging C-arm can now move quickly and in new ways, the company claims that “the areas of the cranial base and skull cap can now be...
Source: Medgadget - March 4, 2019 Category: Medical Devices Authors: Editors Tags: Cardiac Surgery Cardiology Neurology Neurosurgery Radiology Vascular Surgery Source Type: blogs

Digital Health: The Next Big Exit for the Startup Nation?
When people refer to Israel as the “Startup Nation,” it’s usually regarding the country’s innovation in computers, networking, communications, electronics, and so on. But it might be even more appropriate to use that term when discussing life sciences, medical technology, and biotech – areas where Israeli companies and technologies have taken center stage, leading the world with innovations that are saving lives. For a country of barely 8 million people, Israel is a hotbed of medtech investment and innovation. There are over 1,500 companies in the life sciences field in Israel; in 2017, Israeli life scien...
Source: Medgadget - March 4, 2019 Category: Medical Devices Authors: MEDinISRAEL Tags: Sponsored Content Source Type: blogs

Bilateral ICA block: MRI
Case Report 76 yrs old female pt. presets for MR brain angio with c/o giddiness of long duration.MRA shows– marked narrowing& grossly reduced flow signal of both ICA in carotid canal with complete absence of cavernous ICA with source images suggesting right PCOM feeding ipsilateral MCA& left MCA possibly filling from right side. Both MCA are grossly reduced in caliber with origins not identified along with poorly visualized both ACA& ACOM.Dominant grossly tortuous& atheromatous vertebral system with basilar artery suggesting tortuosity/atheromatous looping / redundancy with both PCA normal ...
Source: Sumer's Radiology Site - February 23, 2019 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Critical gaps in STEMI knowledge base : What is the relationship between “ Time window ” and “ Age ” of IRA thrombus ?
Cardiologists are grappling with at least  half a dozen time windows  in the management of STEMI. (It can be combinations of any of the following :Symptom – DAPT Loading – Door – Needle /Balloon-Sheath, wire crossing etc ) Time windows are Important in choosing the right (or no)modality of re-perfusion . Though superiority of  primary PCI  is thought to be established in academic community , it  may not be in real world. Published studies that suggest pPCI is superior to lysis at any time window  still lack good evidence. Why is this long drawn confusion  ?  One of the important determinant of...
Source: Dr.S.Venkatesan MD - February 9, 2019 Category: Cardiology Authors: dr s venkatesan Tags: cath lab tips and tricks PCI PTCA Hardware Primary -PCI STEMI STEMI -Managment STEMI-Primary PCI Thrombolysis how to estimate the age of thrombus in stemi acs soft vs hard thrombus in stemi thrombus hardening time thrombus organising t Source Type: blogs

Digital Thermography and Machine Learning Team Up to Improve Burn Wound Care
A team at McGill University in Canada and the Universidad Autonoma de San Luis Potosi in Mexico have developed a system for analyzing thermographic scans of burn wounds to improve how they are analyzed and how patients are treated. The team used digital infrared thermography, a non-invasive imaging technique, to study wounds when they were presented and for the following few days afterward. Infrared thermography shows the heat signature of the tissues being observed, which can indicate a variety of underlying processes taking place, particularly the amount of blood perfusion below the surface. “Digital infrared thermog...
Source: Medgadget - February 7, 2019 Category: Medical Devices Authors: Editors Tags: Critical Care Informatics Plastic Surgery Source Type: blogs

MightySat Rx Cleared by FDA to Measure Breathing Rate from Fingertip
Masimo won FDA clearance for its MightySat Rx fingertip pulse oximeter to be used to spot check the respiration rate. A similar clearance was issued by the European Union regulatory authorities in 2017. These days the breathing rate is still counted manually more often than not. Though there are devices in existence, even contact-free ones, that can measure the breathing rate, they tend to be pricey, designed for bedridden patients, and they can’t be properly used in a variety of settings. The MightySat Rx uses the company’s Respiration Rate from the Pleth (RRp) technology to measure a patient’s breathin...
Source: Medgadget - January 30, 2019 Category: Medical Devices Authors: Editors Tags: Anesthesiology Cardiology Critical Care Medicine Source Type: blogs

Why You Might Need a Dose of Sugar in Your MRI
Sugar could become an effective replacement for metal in contrast agents in magnetic resonance tomography analyses, according to researchers from John Hopkins University and Lund University in Sweden.There has been heated debate over the safety of certain contrast agents, and the Food and Drug Administration has  warnedthat gadolinium-based contrast agents (GBCAs) can linger in the brain for months or years after the patient ’s procedure. Using alternatives like sugar could potentially diminish the risk of adverse side effects associated with GBCAs. Studies using animals demonstrated that D-glucose could be a possible b...
Source: radRounds - January 18, 2019 Category: Radiology Authors: Julie Morse Source Type: blogs

iCertainty Contact-Free Perfusion Imaging System Cleared in U.S.
RFPi, a company out of Greenville, North Carolina, won FDA clearance for its iCertainty blood flow and perfusion imaging system. The technology gives clinicians the ability to essentially watch as blood saturates or drains in tissues being worked on, something that typically has to be done using invasive means. The new technology avoids injection of dyes and the use of fluoroscopes that emit ionizing radiation, and may be an alternative to interoperative MRI scanning in some cases. RFPi believes that many surgical procedures can be done faster, more easily, and with fewer complications, particularly where perfusion imaging...
Source: Medgadget - January 15, 2019 Category: Medical Devices Authors: Editors Tags: Plastic Surgery Radiology Vascular Surgery Source Type: blogs

How to ship a dead heart . . . with an assured life on delivery ?
Human body is intertwined collection of lives of Individual organs.We believe death occurs when brain dies , respiration stops and circulation ceases . Curiously ,when life ends , these organs  don’t die as a single unit . These three events can happen in any of the six possible permutations.Each organ takes different times to die after loss of life.It is like a crashed computer , where the mother board /RAM memory may be transferred to another and be functional . Out of these three , heart function appears to be supreme as it can function without the need of brain (Science of brain-death) and keep the body alive w...
Source: Dr.S.Venkatesan MD - January 5, 2019 Category: Cardiology Authors: dr s venkatesan Tags: Heart transplantation donor heart transport transmedics Source Type: blogs

The crazy science of coronary reperfusion : When TIMI 1 & 2 beats “ TIMI 3 ” in the myocardial salvage race . . . cardiologists get confused !
The prime job of cardiologists is to restore coronary blood flow in an emergency fashion. While we do this with reasonable success ,there is still a missing link between our Initial aim and achieved goal. It’s all too common situation in any busy cath lab , to see two similar STEMI patients with identical time window & proximal LAD as IRA , in totally different scenarios. In the first patient we find a trickle of flow in LAD , who is relatively comfortable  with normal LV function (In whom , emergency primary PCI might appear redundant.) While the other patient , even after rapidly established TIMI 3 flow , LV...
Source: Dr.S.Venkatesan MD - December 8, 2018 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs

Fight Aging! Newsletter, December 3rd 2018
This article, however, is more of a commentary on high level strategy and the effects of regulation, coupled with a desire to forge ahead rather than hold back in the matter of treating aging, thus I concur with much more of what is said than is usually the case. For decades, one of the most debated questions in gerontology was whether aging is a disease or the norm. At present, excellent reasoning suggests aging should be defined as a disease - indeed, aging has been referred to as "normal disease." Aging is the sum of all age-related diseases and this sum is the best biomarker of aging. Aging and its diseases ar...
Source: Fight Aging! - December 2, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

News from the Methuselah Foundation: Support this Organization to See More Such Progress in the Future
The Methuselah Foundation is one of the most important non-profits in our longevity science community. It was the original home of the first SENS rejuvenation research programs, and has used our philanthropic support to fund a range of important projects and startups. If you look at many of the advances and initiatives of the past twenty years in our community, behind the scenes you'll find that Methuselah Foundation CEO Dave Gobel was in some way involved. All communities are the sum of their connections, and at the center of ours you will find the Methuselah Foundation and the SENS Research Foundation that it gave rise t...
Source: Fight Aging! - November 28, 2018 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs