Naldemedine-induced opioid withdrawal with restlessness as the predominant symptom in a palliative care setting
We report a terminally ill cancer patient who was diagnosed with opioid withdrawal syndrome (OWS) based on symptoms centered around restlessness and sweating that developed 43 days after administration of naldemedine for OIC.RESULTS: The patient was a 78-year-old woman who was diagnosed with stage IVB uterine sarcoma in October, 1 year prior to her visit to our clinic, and underwent chemotherapy after surgery, but the disease became progressive. Thereafter, metastasis to the fourth thoracic vertebrae (Th4) was identified, and loxoprofen and acetaminophen were started for pain at the metastatic site. Oxycodone hydrochloride...
Source: Palliative and Supportive Care - June 23, 2023 Category: Palliative Care Authors: Ryota Sato Mayumi Ishida Nozomu Uchida Takehiko Sakimoto Takefumi Yamaguchi Yoshitaka Ooya Takao Takahashi Hideki Onishi Source Type: research

Naldemedine-induced opioid withdrawal with restlessness as the predominant symptom in a palliative care setting
We report a terminally ill cancer patient who was diagnosed with opioid withdrawal syndrome (OWS) based on symptoms centered around restlessness and sweating that developed 43 days after administration of naldemedine for OIC.RESULTS: The patient was a 78-year-old woman who was diagnosed with stage IVB uterine sarcoma in October, 1 year prior to her visit to our clinic, and underwent chemotherapy after surgery, but the disease became progressive. Thereafter, metastasis to the fourth thoracic vertebrae (Th4) was identified, and loxoprofen and acetaminophen were started for pain at the metastatic site. Oxycodone hydrochloride...
Source: Palliative and Supportive Care - June 23, 2023 Category: Palliative Care Authors: Ryota Sato Mayumi Ishida Nozomu Uchida Takehiko Sakimoto Takefumi Yamaguchi Yoshitaka Ooya Takao Takahashi Hideki Onishi Source Type: research

Naldemedine-induced opioid withdrawal with restlessness as the predominant symptom in a palliative care setting
We report a terminally ill cancer patient who was diagnosed with opioid withdrawal syndrome (OWS) based on symptoms centered around restlessness and sweating that developed 43 days after administration of naldemedine for OIC.RESULTS: The patient was a 78-year-old woman who was diagnosed with stage IVB uterine sarcoma in October, 1 year prior to her visit to our clinic, and underwent chemotherapy after surgery, but the disease became progressive. Thereafter, metastasis to the fourth thoracic vertebrae (Th4) was identified, and loxoprofen and acetaminophen were started for pain at the metastatic site. Oxycodone hydrochloride...
Source: Palliative and Supportive Care - June 23, 2023 Category: Palliative Care Authors: Ryota Sato Mayumi Ishida Nozomu Uchida Takehiko Sakimoto Takefumi Yamaguchi Yoshitaka Ooya Takao Takahashi Hideki Onishi Source Type: research

Prescription patterns of analgesics in cancer patients with bone metastases in Japan: a retrospective database study
CONCLUSION: In Japanese cancer patients with bone metastases, acetaminophen, NSAIDs, and weak or strong opioids were commonly used; their use increased after SREs developed. Opioid use increased closer to death.PMID:37314600 | DOI:10.1007/s10147-023-02365-3 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - June 14, 2023 Category: Cancer & Oncology Authors: Shingo Sato Hideyuki Tomitori Atsushi Okawa Kyoko Akano Source Type: research

Prescription patterns of analgesics in cancer patients with bone metastases in Japan: a retrospective database study
CONCLUSION: In Japanese cancer patients with bone metastases, acetaminophen, NSAIDs, and weak or strong opioids were commonly used; their use increased after SREs developed. Opioid use increased closer to death.PMID:37314600 | DOI:10.1007/s10147-023-02365-3 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - June 14, 2023 Category: Cancer & Oncology Authors: Shingo Sato Hideyuki Tomitori Atsushi Okawa Kyoko Akano Source Type: research

Prescription patterns of analgesics in cancer patients with bone metastases in Japan: a retrospective database study
CONCLUSION: In Japanese cancer patients with bone metastases, acetaminophen, NSAIDs, and weak or strong opioids were commonly used; their use increased after SREs developed. Opioid use increased closer to death.PMID:37314600 | DOI:10.1007/s10147-023-02365-3 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - June 14, 2023 Category: Cancer & Oncology Authors: Shingo Sato Hideyuki Tomitori Atsushi Okawa Kyoko Akano Source Type: research

Prescription patterns of analgesics in cancer patients with bone metastases in Japan: a retrospective database study
CONCLUSION: In Japanese cancer patients with bone metastases, acetaminophen, NSAIDs, and weak or strong opioids were commonly used; their use increased after SREs developed. Opioid use increased closer to death.PMID:37314600 | DOI:10.1007/s10147-023-02365-3 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - June 14, 2023 Category: Cancer & Oncology Authors: Shingo Sato Hideyuki Tomitori Atsushi Okawa Kyoko Akano Source Type: research

Prescription patterns of analgesics in cancer patients with bone metastases in Japan: a retrospective database study
CONCLUSION: In Japanese cancer patients with bone metastases, acetaminophen, NSAIDs, and weak or strong opioids were commonly used; their use increased after SREs developed. Opioid use increased closer to death.PMID:37314600 | DOI:10.1007/s10147-023-02365-3 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - June 14, 2023 Category: Cancer & Oncology Authors: Shingo Sato Hideyuki Tomitori Atsushi Okawa Kyoko Akano Source Type: research

Prescription patterns of analgesics in cancer patients with bone metastases in Japan: a retrospective database study
CONCLUSION: In Japanese cancer patients with bone metastases, acetaminophen, NSAIDs, and weak or strong opioids were commonly used; their use increased after SREs developed. Opioid use increased closer to death.PMID:37314600 | DOI:10.1007/s10147-023-02365-3 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - June 14, 2023 Category: Cancer & Oncology Authors: Shingo Sato Hideyuki Tomitori Atsushi Okawa Kyoko Akano Source Type: research

Prescription patterns of analgesics in cancer patients with bone metastases in Japan: a retrospective database study
CONCLUSION: In Japanese cancer patients with bone metastases, acetaminophen, NSAIDs, and weak or strong opioids were commonly used; their use increased after SREs developed. Opioid use increased closer to death.PMID:37314600 | DOI:10.1007/s10147-023-02365-3 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - June 14, 2023 Category: Cancer & Oncology Authors: Shingo Sato Hideyuki Tomitori Atsushi Okawa Kyoko Akano Source Type: research