Malvern antibiotics developer Venatorx lands NIH contract worth as much as $44M
A Chester County biopharmaceutical company focused on antibiotics could receive as much as $44.2 million under a research and development contract it received from a division of the National Institute of Health.
The contract was awarded to Venatorx Pharmaceuticals by the National Institute of Allergy and Infectious Diseases (NIAID).
Malvern-based Venatorx will use the funds to advance a novel series of penicillin-binding protein inhibitors it is developing to target multi-drug resistant acinetobacter… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - July 27, 2020 Category: Biotechnology Authors: John George Source Type: news
Many Cases of'Penicillin Allergy' Might Be Mistaken
Title: Many Cases of ' Penicillin Allergy ' Might Be MistakenCategory: Health NewsCreated: 7/8/2020 12:00:00 AMLast Editorial Review: 7/9/2020 12:00:00 AM (Source: MedicineNet Allergies General)
Source: MedicineNet Allergies General - July 9, 2020 Category: Allergy & Immunology Source Type: news
Many Cases of'Penicillin Allergy' Might Be Mistaken
WEDNESDAY, July 8, 2020 -- Penicillin allergy is often unconfirmed in hospital patients, meaning many unnecessarily receive other antibiotics that may be less effective and even harmful, a new study finds.
The researchers analyzed records of nearly... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 8, 2020 Category: General Medicine Source Type: news
Many antibiotic substitutions for self-reported penicillin allergies likely unnecessary
(Massachusetts General Hospital) Diagnostic testings or evaluations show that the vast majority of patient-reported allergies to penicillin could be disproven. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 30, 2020 Category: Infectious Diseases Source Type: news
Penicillin allergy increases risk for use of less-effective antibiotics, study finds
People allergic to penicillin are nearly twice as likely to receive a less-effective antibiotic with more side effects when hospitalized than those who are not allergic to the drug. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 29, 2020 Category: Consumer Health News Source Type: news
CDC Issues Health Advisory on Meningococcal Disease
The CDC on June 18 issued a health advisory notifying physicians about recent case reports of patients with meningococcal disease that is resistant to both penicillin and ciprofloxacin. (Source: AAFP News)
Source: AAFP News - June 22, 2020 Category: Primary Care Source Type: news
Drug-Resistant Meningitis Found in Several US Patients Drug-Resistant Meningitis Found in Several US Patients
The CDC has identified 11 meningococcal isolates with evidence of resistance to penicillin and ciprofloxacin, according to a Health Alert Network health advisory.Medscape Medical News (Source: Medscape Emergency Medicine Headlines)
Source: Medscape Emergency Medicine Headlines - June 18, 2020 Category: Emergency Medicine Tags: Infectious Diseases News Source Type: news
$1.77M award gives Temple researchers chance to investigate therapy for cocaine addiction
(Temple University Health System) Researchers at the Lewis Katz School of Medicine at Temple University have received a new $1.77M grant from the National Institute on Drug Abuse that will allow them to explore whether a drug called clavulanic acid can help patients recover from cocaine use disorder. Clavulanic acid is part of an existing therapy known as Augmentin. Augmentin combines clavulanic acid with the penicillin-related antibiotic amoxicillin and is used for the treatment of bacterial infections. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 15, 2020 Category: International Medicine & Public Health Source Type: news
Non-Penicillin Beta-Lactam Drugs: A CGMP Framework for Preventing Cross-Contamination
Pharmaceutical Quality/Manufacturing Standards (CGMP) (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - May 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news
Study shows ICU patients with low-risk penicillin allergies can be tested and treated
(Vanderbilt University Medical Center) Many patients previously diagnosed with a penicillin allergy can have their allergy label removed after testing and safely undergo treatment with penicillin medications, according to a study published in American Journal of Respiratory and Critical Care Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 2, 2020 Category: International Medicine & Public Health Source Type: news
Hospitals Got $100 Billion in the Stimulus Package. But A Lot of That Could Go Toward Administrative Costs
Hospitals have spent the past few weeks racing to respond to the growing COVID-19 crisis, supplementing shortages of equipment, calling back retired personnel, and transforming entire hospital wings to care for infected patients. So when Congress included $100 billion in the stimulus package passed last week to help hospitals and other health care providers address the pandemic, it was seen as much-needed assistance.
But that’s not the whole story, health care experts say. Due to the patchwork nature of the U.S. health care system, a huge chunk of those emergency funds likely won’t go to lifesaving care or equi...
Source: TIME: Health - April 1, 2020 Category: Consumer Health News Authors: Abigail Abrams Tags: Uncategorized COVID-19 Source Type: news
The Coronavirus Pandemic Is Creating a Drug Supply Crisis Just When We Most Need Medicine
As the world scrambles for a magic pharmaceutical bullet to stop the coronavirus, drugs perceived as cures – despite reed-thin evidence — have vanished from pharmacy shelves. Just last Friday, after President Trump touted the still unproven remedy of a malaria drug, hydroxychloroquine, the Food and Drug Administration lifted a restriction it had imposed on a Indian drug manufacturer with a record of manipulating its quality data, to allow it to make the active ingredient now suddenly in hot demand. With the United States long dependent on foreign drug manufacturers for low-cost medicine and key drug ingredients...
Source: TIME: Health - March 26, 2020 Category: Consumer Health News Authors: Katherine Eban Tags: Uncategorized COVID-19 Source Type: news
Simple Decision Rule Helps Identify People at Low-Risk for Penicillin Allergy Simple Decision Rule Helps Identify People at Low-Risk for Penicillin Allergy
A simple clinical decision rule for penicillin allergy can help doctors and antimicrobial-stewardship programs identify people at low-risk of penicillin allergy at the point of care, report doctors from Australia who developed and validated the PEN-FAST rule.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 19, 2020 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news
Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study
Prescribing macrolide antibiotics during the first trimester of pregnancy was associated with an increased risk of any major malformation and specifically cardiovascular malformations compared with penicillin antibiotics. Macrolide prescribing in any trimester was associated with an increased risk of genital malformations. These findings show that macrolides should be used with caution during pregnancy and if feasible alternative antibiotics should be prescribed until further research is available. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 26, 2020 Category: Consumer Health News Source Type: news
Common Antibiotics Linked To Increased Risk Of Birth Defects, Study Says
(CNN) — Taking some common antibiotics during the first trimester of pregnancy was linked with higher risk of birth defects, according to a new study.
The study, published Wednesday in the medical journal BMJ, found an increased risk of birth defects in the children of women who were prescribed macrolides during the first three months of pregnancy compared to mothers who were prescribed penicillin.
Macrolide antibiotics include erythromycin, clarithromycin and azithromycin, and they are used to treat infections, such as pneumonia, bronchitis and urinary, skin and sexually transmitted diseases. They are often prescrib...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 20, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Source Type: news
