Treating Childhood Social Anxiety Disorder With Virtual Environments and Serious Games: A Randomized Trial
Behav Ther. 2021 Nov;52(6):1351-1363. doi: 10.1016/j.beth.2021.03.003. Epub 2021 Mar 18.ABSTRACTDisseminating efficacious psychological treatments remains a challenge for researchers and clinicians. In the case of social anxiety disorder (SAD), Social Effectiveness Therapy for Children (SET-C) has been demonstrated as an efficacious intervention, but elements of the protocol, such as peer generalization sessions, remain challenging to conduct in typical clinical settings. To address this need, we developed an artificially intelligent, web-based application, Pegasys-VR™, designed to replace peer generalization sessions an...
Source: Behavior Therapy - October 17, 2021 Category: Psychiatry & Psychology Authors: Deborah C Beidel Peter W Tuerk Josh Spitalnick Clint A Bowers Krystal Morrison Source Type: research

Treating Childhood Social Anxiety Disorder With Virtual Environments and Serious Games: A Randomized Trial
Behav Ther. 2021 Nov;52(6):1351-1363. doi: 10.1016/j.beth.2021.03.003. Epub 2021 Mar 18.ABSTRACTDisseminating efficacious psychological treatments remains a challenge for researchers and clinicians. In the case of social anxiety disorder (SAD), Social Effectiveness Therapy for Children (SET-C) has been demonstrated as an efficacious intervention, but elements of the protocol, such as peer generalization sessions, remain challenging to conduct in typical clinical settings. To address this need, we developed an artificially intelligent, web-based application, Pegasys-VR™, designed to replace peer generalization sessions an...
Source: Behavior Therapy - October 17, 2021 Category: Psychiatry & Psychology Authors: Deborah C Beidel Peter W Tuerk Josh Spitalnick Clint A Bowers Krystal Morrison Source Type: research

Treating Childhood Social Anxiety Disorder With Virtual Environments and Serious Games: A Randomized Trial
Behav Ther. 2021 Nov;52(6):1351-1363. doi: 10.1016/j.beth.2021.03.003. Epub 2021 Mar 18.ABSTRACTDisseminating efficacious psychological treatments remains a challenge for researchers and clinicians. In the case of social anxiety disorder (SAD), Social Effectiveness Therapy for Children (SET-C) has been demonstrated as an efficacious intervention, but elements of the protocol, such as peer generalization sessions, remain challenging to conduct in typical clinical settings. To address this need, we developed an artificially intelligent, web-based application, Pegasys-VR™, designed to replace peer generalization sessions an...
Source: Behavior Therapy - October 17, 2021 Category: Psychiatry & Psychology Authors: Deborah C Beidel Peter W Tuerk Josh Spitalnick Clint A Bowers Krystal Morrison Source Type: research

Treating Childhood Social Anxiety Disorder With Virtual Environments and Serious Games: A Randomized Trial
Behav Ther. 2021 Nov;52(6):1351-1363. doi: 10.1016/j.beth.2021.03.003. Epub 2021 Mar 18.ABSTRACTDisseminating efficacious psychological treatments remains a challenge for researchers and clinicians. In the case of social anxiety disorder (SAD), Social Effectiveness Therapy for Children (SET-C) has been demonstrated as an efficacious intervention, but elements of the protocol, such as peer generalization sessions, remain challenging to conduct in typical clinical settings. To address this need, we developed an artificially intelligent, web-based application, Pegasys-VR™, designed to replace peer generalization sessions an...
Source: Behavior Therapy - October 17, 2021 Category: Psychiatry & Psychology Authors: Deborah C Beidel Peter W Tuerk Josh Spitalnick Clint A Bowers Krystal Morrison Source Type: research

The use of pegylated interferon a-2a in a cohort of Greek patients with mycosis fungoides
IFN a with its cytotoxic and immunological effects on tumorous T cells has been introduced in the treatment of cutaneous T-cell lymphoma since the 1980s. The reported experience (average response rates 45 –80%, further improved with combination schemes) is mostly based on the use of the recombinant IFN a-2a or IFN a-2b. However, these interferon formulations are no longer commercially available in Europe and therefore, the pegylated analogue (pegylated IFN a-2a, Pegasys; Hoffmann-La Roche) has been currently used to treat CTCLs. (Source: European Journal of Cancer)
Source: European Journal of Cancer - October 1, 2021 Category: Cancer & Oncology Authors: Aikaterini Patsatsi, Evangelia Papadavid, Elisavet Georgiou, Aikaterini Kyriakou, Triantafyllia Koletsa, Chrysostomos Avgeros, Marios Koumourtzis, Kyriaki Lampadaki, Athanasios Tsamaldoupis, Elizabeth Lazaridou, Alexandros Stratigos, Vassiliki Nikolaou Tags: POSTER PRESENTATIONS: TREATMENTS Source Type: research

Viruses, Vol. 13, Pages 1768: Nafamostat –Interferon-α Combination Suppresses SARS-CoV-2 Infection In Vitro and In Vivo by Cooperatively Targeting Host TMPRSS2
Viruses, Vol. 13, Pages 1768: Nafamostat–Interferon-α Combination Suppresses SARS-CoV-2 Infection In Vitro and In Vivo by Cooperatively Targeting Host TMPRSS2 Viruses doi: 10.3390/v13091768 Authors: Aleksandr Ianevski Rouan Yao Hilde Lysvand Gunnveig Grødeland Nicolas Legrand Valentyn Oksenych Eva Zusinaite Tanel Tenson Magnar Bjørås Denis E. Kainov SARS-CoV-2 and its vaccine/immune-escaping variants continue to pose a serious threat to public health due to a paucity of effective, rapidly deployable, and widely available treatments. Here, we address these challenges by combining Pegasys (IFN...
Source: Viruses - September 4, 2021 Category: Virology Authors: Aleksandr Ianevski Rouan Yao Hilde Lysvand Gunnveig Gr ødeland Nicolas Legrand Valentyn Oksenych Eva Zusinaite Tanel Tenson Magnar Bj ørås Denis E. Kainov Tags: Brief Report Source Type: research

Peginterferon Alfa-2a (40KD) Plus Lamivudine or Entecavir in Children With Immune-Tolerant Chronic Hepatitis B
Conclusions: The antiviral regimen evaluated in this trial had an acceptable tolerability profile, but was ineffective in children and adolescents with immune-tolerant CHB. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - August 1, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Evolution of hepatitis C virus genotype 1a vs. 1b distribution in  Germany between 2004 and 2018 - An analysis of 17093 patients from different real world registries
CONCLUSION: A marked increase of GT1a infection associated with drug use was observed in men, but not women, in Germany between 2004 and 2018. The present data show a fundamental change in HCV epidemiology, which has an impact on therapy management and general care of hepatitis C patients in Germany.PMID:33684956 | DOI:10.1055/a-1332-2214 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 8, 2021 Category: Gastroenterology Authors: Karl-Georg Simon Yvonne Serfert Peter Buggisch Stefan Mauss Klaus H W Boeker Hartwig Klinker Tobias M üller Uta Merle Dietrich H üppe Michael P Manns Heiner Wedemeyer Source Type: research

Evolution of hepatitis C virus genotype 1a vs. 1b distribution in  Germany between 2004 and 2018 - An analysis of 17093 patients from different real world registries
CONCLUSION: A marked increase of GT1a infection associated with drug use was observed in men, but not women, in Germany between 2004 and 2018. The present data show a fundamental change in HCV epidemiology, which has an impact on therapy management and general care of hepatitis C patients in Germany.PMID:33684956 | DOI:10.1055/a-1332-2214 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 8, 2021 Category: Gastroenterology Authors: Karl-Georg Simon Yvonne Serfert Peter Buggisch Stefan Mauss Klaus H W Boeker Hartwig Klinker Tobias M üller Uta Merle Dietrich H üppe Michael P Manns Heiner Wedemeyer Source Type: research

Evolution of hepatitis C virus genotype 1a vs. 1b distribution in  Germany between 2004 and 2018 - An analysis of 17093 patients from different real world registries
CONCLUSION: A marked increase of GT1a infection associated with drug use was observed in men, but not women, in Germany between 2004 and 2018. The present data show a fundamental change in HCV epidemiology, which has an impact on therapy management and general care of hepatitis C patients in Germany.PMID:33684956 | DOI:10.1055/a-1332-2214 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 8, 2021 Category: Gastroenterology Authors: Karl-Georg Simon Yvonne Serfert Peter Buggisch Stefan Mauss Klaus H W Boeker Hartwig Klinker Tobias M üller Uta Merle Dietrich H üppe Michael P Manns Heiner Wedemeyer Source Type: research

Evolution of hepatitis C virus genotype 1a vs. 1b distribution in  Germany between 2004 and 2018 - An analysis of 17093 patients from different real world registries
CONCLUSION: A marked increase of GT1a infection associated with drug use was observed in men, but not women, in Germany between 2004 and 2018. The present data show a fundamental change in HCV epidemiology, which has an impact on therapy management and general care of hepatitis C patients in Germany.PMID:33684956 | DOI:10.1055/a-1332-2214 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 8, 2021 Category: Gastroenterology Authors: Karl-Georg Simon Yvonne Serfert Peter Buggisch Stefan Mauss Klaus H W Boeker Hartwig Klinker Tobias M üller Uta Merle Dietrich H üppe Michael P Manns Heiner Wedemeyer Source Type: research

Evolution of hepatitis C virus genotype 1a vs. 1b distribution in  Germany between 2004 and 2018 - An analysis of 17093 patients from different real world registries
CONCLUSION: A marked increase of GT1a infection associated with drug use was observed in men, but not women, in Germany between 2004 and 2018. The present data show a fundamental change in HCV epidemiology, which has an impact on therapy management and general care of hepatitis C patients in Germany.PMID:33684956 | DOI:10.1055/a-1332-2214 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 8, 2021 Category: Gastroenterology Authors: Karl-Georg Simon Yvonne Serfert Peter Buggisch Stefan Mauss Klaus H W Boeker Hartwig Klinker Tobias M üller Uta Merle Dietrich H üppe Michael P Manns Heiner Wedemeyer Source Type: research

Evolution of hepatitis C virus genotype 1a vs. 1b distribution in  Germany between 2004 and 2018 - An analysis of 17093 patients from different real world registries
CONCLUSION: A marked increase of GT1a infection associated with drug use was observed in men, but not women, in Germany between 2004 and 2018. The present data show a fundamental change in HCV epidemiology, which has an impact on therapy management and general care of hepatitis C patients in Germany.PMID:33684956 | DOI:10.1055/a-1332-2214 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 8, 2021 Category: Gastroenterology Authors: Karl-Georg Simon Yvonne Serfert Peter Buggisch Stefan Mauss Klaus H W Boeker Hartwig Klinker Tobias M üller Uta Merle Dietrich H üppe Michael P Manns Heiner Wedemeyer Source Type: research

Evolution of hepatitis C virus genotype 1a vs. 1b distribution in  Germany between 2004 and 2018 - An analysis of 17093 patients from different real world registries
CONCLUSION: A marked increase of GT1a infection associated with drug use was observed in men, but not women, in Germany between 2004 and 2018. The present data show a fundamental change in HCV epidemiology, which has an impact on therapy management and general care of hepatitis C patients in Germany.PMID:33684956 | DOI:10.1055/a-1332-2214 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 8, 2021 Category: Gastroenterology Authors: Karl-Georg Simon Yvonne Serfert Peter Buggisch Stefan Mauss Klaus H W Boeker Hartwig Klinker Tobias M üller Uta Merle Dietrich H üppe Michael P Manns Heiner Wedemeyer Source Type: research

Virological and immunological predictors of long term outcomes of peginterferon alfa-2a therapy for HBeAg-negative chronic hepatitis B
Publication date: Available online 16 December 2020Source: Journal of the Formosan Medical AssociationAuthor(s): I-Cheng Lee, Chien-Wei Su, Keng-Hsin Lan, Yuan-Jen Wang, Kuei-Chuan Lee, Han-Chieh Lin, Ming-Chih Hou, Yi-Hsiang Huang (Source: Journal of the Formosan Medical Association)
Source: Journal of the Formosan Medical Association - December 16, 2020 Category: General Medicine Source Type: research