Increased DNA methylation contributes to the early ripening of pear fruits during domestication and improvement
DNA methylation is an essential epigenetic modification. However, its contribution to trait changes and diversity in the domestication of perennial fruit trees remains unknown. (Source: Genome Biology)
Source: Genome Biology - April 5, 2024 Category: Genetics & Stem Cells Authors: Bobo Song, Jinshan Yu, Xiaolong Li, Jiaming Li, Jing Fan, Hainan Liu, Weilin Wei, Lingchao Zhang, Kaidi Gu, Dongliang Liu, Kejiao Zhao and Jun Wu Tags: Research Source Type: research

Indicaxanthin prevents eryptosis induced by cigarette smoke extract by interfering with active Fas ‐mediated signaling
In conclusion, Ind concentrations comparable to nutritionally relevant plasma concentrations, can prevent Fas-mediated RBC death signaling induced by CSE, which suggests that di etary intake of cactus pear fruits may limit the deleterious effects of cigarette smoking. (Source: BioFactors)
Source: BioFactors - March 24, 2024 Category: Biochemistry Authors: Ignazio Restivo, Ilenia Concetta Giardina, Rosario Barone, Antonio Cilla, Stefano Burgio, Mario Allegra, Luisa Tesoriere, Alessandro Attanzio Tags: RESEARCH ARTICLE Source Type: research

Multi-omics provide insights into the regulation of DNA methylation in pear fruit metabolism
Extensive research has been conducted on fruit development in crops, but the metabolic regulatory networks underlying perennial fruit trees remain poorly understood. To address this knowledge gap, we conduct a... (Source: Genome Biology)
Source: Genome Biology - March 14, 2024 Category: Genetics & Stem Cells Authors: Chao Gu, Mao-Song Pei, Zhi-Hua Guo, Lei Wu, Kai-Jie Qi, Xue-Ping Wang, Hong Liu, Zhongchi Liu, Zhaobo Lang and Shaoling Zhang Tags: Research Source Type: research

Molecules, Vol. 29, Pages 1144: SAR, Molecular Docking and Molecular Dynamic Simulation of Natural Inhibitors against SARS-CoV-2 Mpro Spike Protein
riq Mahmood The SARS-CoV-2 virus and its mutations have affected human health globally and created significant danger for the health of people all around the world. To cure this virus, the human Angiotensin Converting Enzyme-2 (ACE2) receptor, the SARS-CoV-2 main protease (Mpro), and spike proteins were found to be likely candidates for the synthesis of novel therapeutic drug. In the past, proteins were capable of engaging in interaction with a wide variety of ligands, including both manmade and plant-derived small molecules. Pyrus communis L., Ginko bibola, Carica papaya, Syrian rue, and Pimenta dioica were some of th...
Source: Molecules - March 4, 2024 Category: Chemistry Authors: Aqsa Salamat Naveen Kosar Ayesha Mohyuddin Muhammad Imran Muhammad Nauman Zahid Tariq Mahmood Tags: Article Source Type: research

Identification and expression analysis of ATP-binding cassette (ABC) transporters revealed its role in regulating stress response in pear (Pyrus bretchneideri)
ATP-binding cassette (ABC) transporter proteins constitute a plant gene superfamily crucial for growth, development, and responses to environmental stresses. Despite their identification in various plants like... (Source: BMC Genomics)
Source: BMC Genomics - February 12, 2024 Category: Genetics & Stem Cells Authors: Xiaobing Kou, Zhen Zhao, Xinqi Xu, Chang Li, Juyou Wu and Shaoling Zhang Tags: Research Source Type: research

Genes, Vol. 15, Pages 184: Involvement of Alfin-Like Transcription Factors in Plant Development and Stress Response
g Juan Wang Alfin-like (AL) proteins are an important class of transcription factor (TF) widely distributed in eukaryotes and play vital roles in many aspects of plant growth and development. AL proteins contain an Alfin-like domain and a specific PHD-finger structure domain at the N-terminus and C-terminus, respectively. The PHD domain can bind to a specific (C/A) CAC element in the promoter region and affect plant growth and development by regulating the expression of functional genes. This review describes a variety of AL transcription factors that have been isolated and characterized in Arabidopsis thaliana, Bras...
Source: Genes - January 29, 2024 Category: Genetics & Stem Cells Authors: Ruixin Jin Haitao Yang Tayeb Muhammad Xin Li Diliaremu Tuerdiyusufu Baike Wang Juan Wang Tags: Review Source Type: research

Aabrm1-mediated melanin synthesis is essential to growth and development, stress adaption, and pathogenicity in Alternaria alternata
Scytalone dehydratase (brm1) is one of the key enzymes in 1, 8-dihydroxynaphthalene (DHN) melanin synthesis, which mediates melanin biosythesis and regulates cell biological process of plant fungi, but its function in Alternaria alternata, the causal agent of pear black spot, is unclear. Brm1 in A. alternata was cloned, identified, and named as Aabrm1. An Aabrm1-deletion mutant was generated and revealed that the deletion of Aabrm1 leads to a significant decrease in melanin production and forms orange colony smooth spores. In addition, the deletion of Aabrm1 gene impaired infection structure information and penetration. Th...
Source: Frontiers in Microbiology - January 11, 2024 Category: Microbiology Source Type: research

Comparative physiological, metabolomic and transcriptomic analyses reveal the mechanisms of differences in pear fruit quality between distinct training systems
Canopy architecture is critical in determining the fruit-zone microclimate and, ultimately, in determining an orchard ’s success in terms of the quality and quantity of the fruit produced. However, few studies ... (Source: BMC Plant Biology)
Source: BMC Plant Biology - January 4, 2024 Category: Biology Authors: Zheng Liu, Xie-Yu Li, Li Yang, Yin-Sheng Cheng, Xian-Shuang Nie and Tao Wu Tags: Research Source Type: research

Genome-wide identification of the Pyrus R2R3-MYB gene family and PhMYB62 regulation analysis in Pyrus hopeiensis flowers at low temperature
In this study, a total of 122 PcoR2R3-MYB genes were identified and grouped into 26 clades in pear. And these PcoMYBs were unevenly distributed among 17 chromosomes. The sequence characteristics, conversed motifs, exon/intron structures, classification, duplication events and cis-acting elements were also investigated. The gene duplication events showed that segmental duplication may play key roles in expansion of the PcoMYB gene family. Pyrus hopeiensis, which is a valuable wild resource, has strong cold resistance. An integrative analyses of miRNA and mRNA showed that PhMYB62 was involved in regulating low-temperature st...
Source: International Journal of Biological Macromolecules - December 9, 2023 Category: Biochemistry Authors: Yongtan Li Jun Zhang Shijie Wang Yichao Liu Minsheng Yang Yinran Huang Source Type: research

Functional and kinetics of two efficient phenylalanine ammonia lyase from Pyrus bretschneideri
The enzyme phenylalanine ammonia lyase (PAL) controls the transition from primary to secondary metabolism by converting L-phenylalanine (L-Phe) to cinnamic acid. However, the function of PAL in pear plants (Pyrus... (Source: BMC Plant Biology)
Source: BMC Plant Biology - December 2, 2023 Category: Biology Authors: Guohui Li, Cheng Song, Muhammad Aamir Manzoor, Daoyuan Li, Yunpeng Cao and Yongping Cai Tags: Research Source Type: research

Specific functions of single pistil S-RNases in S-gene homozygous Pyrus germplasm
Gametophytic self-incompatibility (SI) is regulated by S-allele recognition; that is, pollen in a style with the same S-genotype will undergo programmed cell death and stop growing so that it is unable to complet... (Source: BMC Plant Biology)
Source: BMC Plant Biology - November 20, 2023 Category: Biology Authors: Yongjie Qi, Zhenghui Gao, Na Ma, Liqing Lu, Fanjun Ke, Shaoling Zhang and Yiliu Xu Tags: Research Source Type: research

Morphology and Molecular Characterization of a Fungus from the < em > Alternaria alternata < /em > Species Complex Causing Black Spots on < em > Pyrus sinkiangensis < /em > (Koerle pear)
Mycobiology. 2020 Apr 14;48(3):233-239. doi: 10.1080/12298093.2020.1745476. eCollection 2020.ABSTRACTA small-spored Alternaria was found from black spots of storaged Koerle pear (Pyrus sinkiangensis), one of the economically important fruit in Xinjiang province, China. The morphology is similar to A. limoniasperae but obviously different in secondary conidiophores and conidial septa. A phylogenetic analysis using sequence datasets of ITS, GAPDH, TEF1, RPB2, Alt a1, OPA10-2, and EndoPG genes revealed that it belonged to the Alternaria alternata complex group. Pathogenicity tests illustrated that the fungus was the causal pa...
Source: Mycobiology - November 16, 2023 Category: Biology Authors: Sein Lai Lai Aung Hai Feng Liu Dong Fang Pei Bing Bin Lu May Moe Oo Jian Xin Deng Source Type: research

GSE225720 MicroRNAs in Pyrus stigma tissue and stigma exudates
Contributors : Vivek Ambastha ; Yuval Nevo ; Ifat Matityhu ; David Honys ; Yehoram LeshemSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Pyrus communis ; Pyrus pyrifolia ; Pyrus syriacaIn many plant species, flower stigma secretions are important in early stages of sexual reproduction. Previous chemical analysis and proteomic characterization of these exudates provided insights into their biological function. Nevertheless, the presence of nucleic acids in the stigma exudates has not been previously reported. Here we studied the stigma exudates of Pyrus communis, Pyrus pyrifolia and Pyrus...
Source: GEO: Gene Expression Omnibus - November 15, 2023 Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by high throughput sequencing Pyrus communis Pyrus pyrifolia Pyrus syriaca Source Type: research

Pyrus pashia fruit extract and its major phytometabolite chrysin prevent hippocampal apoptosis and memory impairment in PTZ-kindled mice
. (Source: Nutritional Neuroscience)
Source: Nutritional Neuroscience - November 6, 2023 Category: Nutrition Authors: Priyanka SharmaAmita KumariPadmanabh SinghSweta SrivasMahendra K. ThakurSiva Hemalathaa Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, Indiab Academy of Scientific and Innovativ Source Type: research