The Two Faces of p53: Tumor Suppressor and Oncogene
NCI’s Center for Cancer Research (CCR) Grand Rounds
Dr. Carol Prives is the DaCosta Professor of Biological Sciences at Columbia University. She was educated in Canada, receiving her BSc and PhD from McGill University. After postdoctoral training at Albert Einstein College of Medicine and the Weizmann Institute, she became a faculty member at the Weizmann in Israel after which she joined the Biological Sciences Department at Columbia University where she was appointed to a named professorship in 1995. Dr Prives served as Chair of that department between 2000 and 2004. Since the late 1980’s her work has focused on th...
Source: Videocast - All Events - June 13, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Connecting Tumor Suppression and Fate Determination in Mammary Cancer Stem Cells: From Discovery to Preclinical Intervention
NCI’s Center for Cancer Research (CCR) Grand Rounds
Prof. Pier Paolo Di Fiore is group leader at IFOM, an internationally competitive research institute in Milan, which he founded in 1998, and Director of the Molecular Medicine Program at IEO, a leading cancer care center in Milan. He is also Full Professor of General Pathology at the University of Milan, and co-founder of the post-graduate European School of Molecular Medicine.
Dr. Di Fiore has dedicated his scientific career to deciphering the molecular mechanisms of cellular transformation, with emphasis on growth factor receptor signaling, endocytosis and stem cel...
Source: Videocast - All Events - June 6, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Controlling Global Transcriptome Output with MYC, Supercoils, and Topoisomerase
NCI’s Center for Cancer Research (CCR) Grand Rounds
Dr. Levens received his M.D. and Ph.D. from the University of Chicago. Subsequently, he completed residency training in anatomic pathology at the Laboratory of Pathology, NCI, where he is now the chief of the Gene Regulation Section. Dr. Levens studies fundamental mechanisms of gene regulation, emphasizing the control of MYC function and expression. He and his team showed that MYC amplifies is a universal amplifier of gene expression. This explains much of MYC physiology and pathology, but also defines the need to control MYC levels precisely in real time. The Leven...
Source: Videocast - All Events - April 19, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Long Non-coding RNAs and the Homeostasis of Innate Immune Cells
Presented by: Jorge Henao-Mejia, M.D., Ph.D.; Assistant Professor of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of MedicineCategory: ImmunologyAired date: 04/06/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - April 7, 2016 Category: Journals (General) Tags: Past Events Source Type: video
Role and Regulation of the NLRP3 Inflammasome
Presented by: Gabriel Nuñez, M.D.; Paul de Kruif Endowed Professor in Academic Pathology; Department of Pathology, University of Michigan School of MedicineCategory: ImmunologyAired date: 03/16/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - March 17, 2016 Category: Journals (General) Tags: Past Events Source Type: video
Role and Regulation of the NLRP3 Inflammasome.
Immunology Interest Group
Gabriel Nuñez earned his M.D. degree from the University of Seville, Spain, in 1977. He received postdoctoral training in Immunology at the University of Texas Southwestern Medical Center, Dallas (1979–1984) and residency training in Anatomical Pathology at Washington University in St Louis (1985–1990). In 1987, he joined the laboratory of Stanley Korsmeyer at Washington University, where he studied the function of the anti-apoptotic protein BCL-2. In 1991, he joined the Department of Pathology at the University of Michigan in Ann Arbor as an Assistant Professor and was promoted to full Prof...
Source: Videocast - All Events - March 14, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
How to Maintain Serum Antibody Titers?
Presented by: David M. Allman, Ph.D.; Associate Professor of Pathology and Laboratory Medicine, Perelman School of Medicine, University of PennsylvaniaCategory: ImmunologyAired date: 03/09/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - March 10, 2016 Category: Journals (General) Tags: Past Events Source Type: video
Demystifying Medicine 2016: How Long Can and Should We Live & What Centenarians Teach Us about Aging
Demystifying Medicine is an annual course from January to May designed to help bridge the gap between advances in biology and their application to major human diseases. The course includes presentation of patients, pathology, diagnosis, and therapy in the context of major disease problems and current research, primarily directed toward Ph.D. students, fellows, and staff. All are invited.For more information go to https://demystifyingmedicine.od.nih.gov/Air date: 5/17/2016 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - March 4, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
How to Maintain Serum Antibody Titers?
Immunology Interest Group
David Allman is an Associate Professor of Pathology and Laboratory Medicine in the Department of Pathology and Laboratory Medicine of the Perelman School of Medicine at the University of Pennsylvania. He described what are now called transitional B cells during his PhD. This work showed that B cell maturation and formation of the B cell repertoire is completed in peripheral lymphoid tissues rather than in the bone marrow. Later, working with Warren Pear, he established roles for Notch in T lineage commitment. Recently he has focused on antibody secreting plasma cells, and has discovered that T-c...
Source: Videocast - All Events - March 2, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Clinical Cases from the NIH Clinical Center: From Pathogenesis to Treatment of Chronic Atypical Neutrophilic Dermatosis with Lipodystrophy and Elevated Temperature Syndrome (CANDLE), a Rare Type I IFN-mediated Autoinflammatory Disease
Presented by: Lead Presenters: Gina Montealegre, MD, MPH Staff Clinician, Translational Autoinflammatory Disease Section, NIAMS, NIH; Chyi-Chia Richard Lee, MD, PhD Staff Clinician and Dermatopathologist, Laboratory of Pathology, Center for Cancer Research, NCI, NCategory: Clinical Center Grand RoundsAired date: 02/17/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - February 18, 2016 Category: Journals (General) Tags: Past Events Source Type: video
Demystifying Medicine 2016: Shingles (Herpes Zoster) Revisited
Demystifying Medicine is an annual course from January to May designed to help bridge the gap between advances in biology and their application to major human diseases. The course includes presentation of patients, pathology, diagnosis, and therapy in the context of major disease problems and current research, primarily directed toward Ph.D. students, fellows, and staff. All are invited.For more information go to https://demystifyingmedicine.od.nih.gov/
Air date: 2/23/2016 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 18, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Demystifying Medicine 2016: Atopy: The Common and The Rare Allergies in the Genomic Era
Demystifying Medicine is an annual course from January to May designed to help bridge the gap between advances in biology and their application to major human diseases. The course includes presentation of patients, pathology, diagnosis, and therapy in the context of major disease problems and current research, primarily directed toward Ph.D. students, fellows, and staff. All are invited.For more information go to https://demystifyingmedicine.od.nih.gov/
Air date: 2/16/2016 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 10, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
When Watson and Crick Get Linked: DNA Interstrand Crosslink Repair and Human Disease
NCI’s Center for Cancer Research (CCR) Grand Rounds
Dr. Smogorzewska received her B.S. in molecular biology and biochemistry from the University of Southern California in 1995, her Ph.D. from The Rockefeller University in 2002 where she was mentored by Dr. Titia de Lange and her M.D. from Weill Cornell Medical College in 2003. Following a residency in clinical pathology at Massachusetts General Hospital, she joined Harvard Medical School as a postdoctoral fellow in Stephen Elledge's lab in 2005. She joined The Rockefeller University as an assistant professor in 2009 and was promoted to associate professor in 2015.
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Source: Videocast - All Events - February 1, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Action and Traction at the Immunological Synapse
Presented by: Janis Burkhardt, Ph.D.; Professor of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine; and Evelyn & George Willing Endowed Chair in Pathology Research, Children’s Hospital of PhiladelphiaCategory: ImmunologyAired date: 01/20/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - January 21, 2016 Category: Journals (General) Tags: Past Events Source Type: video
Modulation of T Cell Signaling by ITK.
Presented by: Leslie Berg, Ph.D.; Professor Department of Pathology, University of Massachusetts Medical School, WorcesterCategory: ImmunologyAired date: 01/13/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - January 14, 2016 Category: Journals (General) Tags: Past Events Source Type: video
