Lantheus to supply PET tracer in large U.S. trial
Lantheus Medical Imaging will supply its experimental F-18-labeled PET imaging radiotracer MK-6240 for a large U.S. trial to investigate differences in brain pathology in people with varying types of dementia. The National Institute on Aging-led study is named the Consortium for Clarity in ADRD Research Through Imaging (CLARiTI) trial and will involve all 37 Alzheimer’s disease research centers in the U.S. The five-year trial will recruit 2,000 subjects and collect their imaging and blood-based biomarker data to generate etiologic profiles for cases of mixed dementia, the company said. F-18 MK-6240 radiotracer targets ...
Source: AuntMinnie.com Headlines - February 14, 2024 Category: Radiology Authors: AuntMinnie.com staff writers Tags: Industry News Subspecialties Neuroradiology Source Type: news

PET links impaired sleep in Alzheimer ’s disease patients to tau protein
PET scans have revealed specific brain pathology that may drive sleep disturbances in Alzheimer’s disease patients, according to a study published February 8 in the Journal of the Neurological Sciences. In a large group, abnormal nighttime behaviors were linked with greater baseline tau on F-18 flortaucipir PET scans, with the finding offering a potential new target for delaying cognitive decline, noted lead author Ryan Kim, of Harvard University in Cambridge, MA, and colleagues. “Our results help identify high-risk individuals who could benefit from sleep-related interventions aimed to delay cognitive decline and [A...
Source: AuntMinnie.com Headlines - February 13, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Neuroradiology Source Type: news

Digital pathology tech company Proscia gets key FDA clearance
Proscia's Concentriq platform was approved for use in primary cancer diagnosis. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - February 12, 2024 Category: Biotechnology Authors: John George Source Type: news

Proscia Receives FDA 510(k) Clearance For Concentriq AP-Dx
Key regulatory milestone advances company's mission to perfect cancer diagnosis PHILADELPHIA, Feb. 12, 2024 /PRNewswire-PRWeb/ -- Proscia®, a leading provider of digital and computational pathology solutions, has received 510(k) clearance from the United States (U.S.) Food and Drug... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - February 12, 2024 Category: Pharmaceuticals Tags: FDA Source Type: news

Experimental Low-Cost Blood Test Can Detect Multiple Cancers, Researchers Say
Test uses a new ultrasensitive immunoassay to detect a known clinical laboratory diagnostic protein biomarker for many common cancers Researchers from Mass General Brigham, the Dana-Farber Cancer Institute, Harvard University’s Wyss Institute and other institutions around the world have reportedly developed a simple clinical laboratory blood test that can detect a common protein biomarker associated […] The post Experimental Low-Cost Blood Test Can Detect Multiple Cancers, Researchers Say appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - February 12, 2024 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: Laboratory Instruments & Laboratory Equipment Laboratory News Laboratory Pathology Laboratory Resources Laboratory Testing anatomic pathology blood plasma Brigham and Women’s Hospital cancer Cancer Discovery carcinomas clinical lab Source Type: news

Pathological findings in hanging: is the traditional knowledge correct? - Crudele GDL, Amadasi A, Franceschetti L, Cattaneo C.
BACKGROUND: In forensic pathology, asphyxia presents a problem as frequently as it is thorny and challenging. Some knowledge in forensic pathology is still considered to be traditionally acquired and is not critically assessed with modern statistical or te... (Source: SafetyLit)
Source: SafetyLit - February 12, 2024 Category: International Medicine & Public Health Tags: Drowning, Suffocation Source Type: news

The impact of childhood trauma on borderline personality organization in a community sample of Greek emerging adults - Malafanti A, Yotsidi V, Sideridis G, Giannouli E, Galanaki EP, Malogiannis I.
There is limited research on the role of childhood trauma in personality pathology according to Kernberg's psychodynamic model of internalized object relations. Because childhood trauma reflects the disruptions of these relations, it is expected to predict... (Source: SafetyLit)
Source: SafetyLit - February 12, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Evidence grows for use of amyloid PET in China
Chinese clinicians have provided evidence in a “real-world study” that shows amyloid PET imaging is effective for diagnosing and managing patients with Alzheimer’s disease, according to a study published February 8 in Alzheimer’s and Dementia.In patients treated at a memory clinic at Huashan Hospital in Shanghai, amyloid PET scans detected brain pathology associated with the disease and led to changes in treatment plans in 36.5% of patients, noted lead author Ke-Liang Chen, MD, a neurologist at Fudan University.“In this large, real-world study, we found that [beta amyloid]-PET led to the changes in etiological di...
Source: AuntMinnie.com Headlines - February 12, 2024 Category: Radiology Authors: Will Morton Source Type: news

Personality disorder symptoms in intermittent explosive disorder: a latent class analysis - Ciesinski NK, Drabick DAG, Berman ME, McCloskey MS.
Intermittent explosive disorder (IED) is characterized by recurrent reactive aggression. IED is associated with significant personality pathology that is suggestive of higher levels of general personality disorder (PD). However, little is known about how p... (Source: SafetyLit)
Source: SafetyLit - February 9, 2024 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Eliminating racial bias and challenges for black athletes with sports-related concussion: the role of speech-language pathology clinicians and researchers - Davis AS.
PURPOSE: The aim of this tutorial is to highlight racial bias and challenges for Black adult athletes' cognitive-communication disorders associated with sports-related concussion (SRC). The author discusses racial bias in SRC literature and research an... (Source: SafetyLit)
Source: SafetyLit - February 9, 2024 Category: International Medicine & Public Health Tags: Recreational and Sports Issues Source Type: news

Federal Government Bans Elizabeth Holmes from Participating in Government Health Programs for 90 Years
Theranos founder and former CEO continues down the path she began by defrauding her investors and lying to clinical laboratory leaders about her technology’s capabilities In the latest from the Elizabeth Holmes/Theranos scandal, the federal government has banned Holmes from participating in government health programs for 90 years, according to a statement from the US […] The post Federal Government Bans Elizabeth Holmes from Participating in Government Health Programs for 90 Years appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - February 9, 2024 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: Laboratory Instruments & Laboratory Equipment Laboratory News Laboratory Pathology Laboratory Resources Laboratory Testing anatomic pathology Ars Technica Christi Grimm clinical laboratory clinical pathology Dark Daily dark intellige Source Type: news

Corista DP3 ® Platform Receives Class II Medical Device License From Health Canada
DP3's momentum as a world-class integrated pathology solution grows CONCORD, Mass., Feb. 7, 2024 /PRNewswire-PRWeb/ -- Corista, a leader in digital pathology solutions, is excited to announce that it has received a Class II Medical Device License from Health Canada for its DP3 platform.... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - February 7, 2024 Category: Pharmaceuticals Tags: LIC Source Type: news

University Hospitals Birmingham Claims Its New AI Model Detects Certain Skin Cancers with Nearly 100% Accuracy
But dermatologists and other cancer doctors still say AI is not ready to operate without oversight by clinical physicians Dermatopathologists and the anatomic pathology profession in general have a new example of how artificial intelligence’s (AI’s) ability to detect cancer with accuracy comparable to a trained pathologist has greatly improved. At the latest European Academy […] The post University Hospitals Birmingham Claims Its New AI Model Detects Certain Skin Cancers with Nearly 100% Accuracy appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - February 7, 2024 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: Digital Pathology Laboratory Instruments & Laboratory Equipment Laboratory News Laboratory Pathology Laboratory Resources Laboratory Testing AI anatomic pathology artificial intelligence basal cell carcinoma clinical laboratory clini Source Type: news

Even With Alzheimer's Pathology, Healthy Lifestyles May Preserve Cognition
(MedPage Today) -- Cognitive function was better for older adults with healthy lifestyles even if they had Alzheimer's or other dementia-related pathologies, autopsy data showed. A 1-point increase in a healthy lifestyle score was associated with... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - February 6, 2024 Category: Psychiatry Source Type: news

How Do Anogenital Injuries Relate to Rape Accusations? How Do Anogenital Injuries Relate to Rape Accusations?
Clinicians who care for sexual violence survivors must reassure patients that the lack of anogenital injury does not diminish the credibility of their accounts.Medscape Medical News (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - February 5, 2024 Category: Pathology Tags: Ob/Gyn & Women ' s Health Source Type: news